A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
What is the purpose of this study?The phase III trial compares the effect of pembrolizumab to observation for the treatment of patients with early-stage triple-negative breast cancer who achieved a pathologic complete response after preoperative chemotherapy in combination with pembrolizumab. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the …
The primary outcome measure will be the success rates of isolating PAECs from PACs and comparing between the different methods (balloon tip versus aspirated blood), between PH subtypes, and then PH patients and control patients using demographic and objective data obtained from our cohort.
The aim of our study is 1) to analyze the level of senescence markers in periodontally healthy and diseased gingival tissue;2) to analyze the level of senescence markers in periodontal and periimplant diseased gingival tissues and reveal the association between cellular senescence or ageing on progression of periodontal disease and …
Investigate the various barriers that affect adherence to the Ponseti method for clubfoot treatment in the state of IndianaTo assess the impact of these barriers on the rate of missed or discontinued clinic visits within the first three months of treatment
This is an observational prospective study and a retrospective study. For the prospective study, the clinical data and blood sample will be collected in accordance with standard procedure currently used in patient care at our institutions. For the retrospective study, patients requiring acute dialysis in the pediatric ICU and CVICU …
What is the purpose of this study?To establish the recommended phase II dose of a flavored preparation of orally administered irinotecan (VAL-413) when given in combination with temozolomide for five consecutive days. To characterize and compare the pharmacokinetic profiles of VAL-413 and conventional irinotecan given orally To evaluate the palatability …
This proposal will expand on our current work with the SRC/IRB approved project (IRB: #15991 Assessing Household Material Hardship in Children with Central Nervous System (CNS) Tumors). This new population can serve as a comparison, with children admitted to the hospital for infectious diseases and requiring long hospital stays and/or …
Compare the performance of the tests on the i-STAT CG4+ and CG8+ cartridges on the iSTAT 1 analyzer to the performance of the tests on the comparator device, the RAPIDPoint® 500e System or epoc® Blood Analysis System using neonatal capillary whole blood specimens
This protocol describes the epidemiology, international controversy and current state of knowledge regarding long-term maternal outcomes among women with mild CHTN who received antihypertensive therapy in pregnancy or who had preeclampsia. This document is considered a written agreement between participating investigators and their corresponding centers. Changes to the protocol during …
In this prospective and longitudinal natural history study, the aim is to identify variables that affect long-term outcomes following potentially life-saving Definitive Therapy (DT), which includes either 1) allogeneic hematopoietic cell transplant (HCT), or 2) autologous gene therapy (GT).
