A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
What is this study about?Coarctation of the aorta (CoA) tissues contain distinctive cell populations, and comprehensive analysis of these cells will provide understanding of cell abnormalities that are driving CoA. We want to define these types of cells that are abnormally located in the diseased aortic tissues of neonates with …
Measure the levels of key metabolites in maternal blood during pregnancies where the children developed ASD or were typically-developing (TD). If successful, this study will result in a diagnostic test for risk of having a child with ASD, and suggest treatments during pregnancy such as folate, vitamin B12, and carnitine …
What is the purpose of this study?This is a multicenter, prospective, observational Phase 4 study in the United States. The study is designed to collect both medical history and prospective data on Duchenne muscular dystrophy (DMD) treatment outcomes in participants receiving delandistrogene moxeparvovec as part of clinical care, compared to …
What is the purpose of this study?Since its launch in 2004, the overarching aim of the Alzheimer's Disease Neuroimaging Initiative (ADNI) Study has been to validate biomarkers for Alzheimer's disease (AD) clinical trials. ADNI4 continues the previously funded ADNI1, ADNI-GO, ADNI2, and ADNI3 studies that have combined public/private collaborations between …
Placental chorangioma is a rare pregnancy complication but with significant maternal and fetal consequences. Chorangioma is a benign tumor of the placenta. As it grows, it can cause pregnancy complications. Little is known about the natural history of placental chorangioma or its response to in-utero intervention. The aim of this …
What is this study about?This study will determine whether adjuvant chemotherapy (ACT) added to ovarian function suppression (OFS) plus endocrine therapy (ET) is superior to OFS plus ET in improving invasive breast cancer-free survival (IBCFS) among premenopausal, early- stage breast cancer (EBC) patients with estrogen receptor (ER)-positive, HER2-negative tumors and …
This study investigates the effectiveness of using a combination of investigational medications, nivolumab and ipilimumab, compared to nivolumab alone in treating patients with recurrent endometrial cancer. Endometrial cancer is a type of cancer that begins in the lining of the uterus. This study focuses on a specific type of endometrial …
WHY IS THIS STUDY BEING DONE?The main reason for this research study is to understand what happens with patients who are treated for giant omphaloceles (GO) using a non-invasive staged closure technique that uses a hydrocolloid (Duoderm CGF) silo. Omphaloceles are a rare (birth) defect where infants are born with …
What is the purpose of this study?The brain is protected from any toxic or inflammatory molecule by the blood-brain barrier (BBB). This physical barrier is located at the level of the blood vessel walls. Because of these barrier properties, the blood vessels are also impermeable to the passage of therapeutic …
WHY IS THIS STUDY BEING DONE?Autoimmune hepatitis (AIH) is liver inflammation that occurs when the body’s immune system attacks liver cells. It is caused by an overactive immune system, and it is unknown why this happens. The Autoimmune Hepatitis Association (AIHA) is a not-for-profit organization seeking to develop a patient …