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Found 752 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Study on Investigational Medication for ALS, a Disease Affecting Nerve Cells Leading to Muscle Weakness and Paralysis

C
Cynthia Bodkin, MD
18 years - 100 years
All genders
Interventional
This study investigates Amyotrophic Lateral Sclerosis (ALS), a disease that affects nerve cells in the brain and spinal cord. ALS causes muscles to weaken and leads to paralysis. The purpose of this study is to find out if an investigational medication can be safe and effective for people with ALS.Participants …
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A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, MULTICENTER STUDY TO EVALUATE THE SAFETY, EFFICACY, AND PHARMACOKINETICS OF BUDESONIDE EXTENDED-RELEASE TABLETS ADMINISTERED ONCE DAILY IN PEDIATRIC SUBJECTS AGED 5 TO 17 YEARS WITH ACTIVE, MILD TO MODERATE ULCERATIVE COLITIS

M
Marian Pfefferkorn
5 years - 17 years
All genders
Interventional
The primary objective of this study is to evaluate the efficacy and safety of a low and a high dose of budesonide extended-release tablets in pediatric subjects with active, mild to moderate UC.During the study, partiicpants (or their parent / guardian, as appropriate) will be required to document theirdisease symptoms …
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VOLUNTEERS AGES 21-26 NEEDED FOR ALCOHOL AND BRAIN IMAGING STUDY!

VOLUNTEERS AGES 21-26 NEEDED FOR ALCOHOL AND BRAIN IMAGING STUDY!

D
David Kareken, PhD
21 years - 27 years
Accepts healthy volunteer
All genders
Do you drink alcohol? If yes, we want to learn about your brain activity!  Researchers at the IU School of Medicine are looking for volunteers aged 21-27 to participate in an alcohol and brain imaging study.. To learn more about the Principal Investigator David Kareken, PhD and his research interests, please visit this …
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Study on Dosing for Seizure Treatment in Children

G
Gregory Faris
6 months - 13 years
All genders
This study investigates how to improve the dosing of a commonly used medication for seizures called midazolam in children during emergencies. Seizures are episodes of uncontrolled electrical activity in the brain, which can be dangerous if they do not stop on their own. The purpose of this study is to …
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TArgeting Type 1 Diabetes Using POLyamines (TADPOL) (TADPOL)

E
Emily Sims, MD
6 years - 40 years
All genders
Phase 2
Interventional
The goal of this clinical trial is to test a drug known as DFMO in people with Type 1 Diabetes (T1D). The main question[s] it aims to answer are:Does it reduce stress on the cells that make insulin?Does it preserve what is left of the body's insulin production? Participants will …
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A Study Evaluating the Efficacy and Safety of Giredestrant Plus Everolimus Compared With The Physician's Choice of Endocrine Therapy Plus Everolimus in Participants With Estrogen Receptor-Positive, HER2-Negative, Locally Advanced or Metastatic Breast Cancer (evERA Breast Cancer)

B
Bryan Schneider, MD
18 years - 100 years
All genders
Phase 3
Interventional
What is the purpose of this study?This Phase III, randomized, open-label, multicenter study will evaluate the efficacy andy of giredestrant plus everolimus compared with the physician's choice of endocrineherapy plus everolimus in participants with estrogen receptor (ER)-positive, human epidermal growth factor receptor 2 (HER2)-negative locally advanced or metastatic breast cancer …
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Gastroschisis Outcomes of Delivery (GOOD) Study

H
Hiba Mustafa, MD
18 years or above
Female
Phase 3
Interventional
The objective of this study is to investigate the hypothesis that delivery at 35 0/7- 35 6/7 weeks in stable patients with gastroschisis is superior to observation and expectantgement with a goal of delivery at 38 0/7 - 38 6/7 weeks. To test this hypothesis, we willdomized, prospective, multi-institutional trial …
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Neoadjuvant pembrolizumab in patients with muscle-invasive bladder cancer with selective bladder sparing

J
Jennifer King
18 years or above
All genders
Phase 2
Interventional
What is the purpose of this study?Subjects with cT2-T3N0M0 urothelial cancer of the bladder will be enrolled. After completingwo cycles of pembrolizumab, subjects will undergo a restaging MRI of the abdomen and pelvis with a standard acquisition protocol (as outlined in the protocol) as well as CT chest. A CThe …
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Delirium and Neuropsychological Recovery Among Emergency General Surgery Survivors

M
Malaz Boustani, MD
65 years or above
All genders
Interventional
This study will evaluate the usefulness of the Emergency General Surgery (EGS) Delirium Recovery Model. It is hypothesized that the cognitive, physical and psychological recovery ofder EGS delirium survivors will be improved through the use of the EGS Delirium Recoverydel. Participants can expect to be on the study for 18 …
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Selatogrel Outcome Study in Suspected Acute Myocardial Infarction (SOS-AMI)

M
Mohammed Madmani, MD
R
Rolf Kreutz, MD
18 years or above
All genders
Phase 3
Interventional
This study will randomize patients recently discharged from the hospital with a confirmed diagnosis of type 1 acute myocardial infarction (Thygesen et al. 2018) and having additionaldiovascular risk factors.
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