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Found 743 results

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Chemotherapy for the Treatment of Patients With Newly Diagnosed Very Low-Risk and Low Risk Fusion Negative Rhabdomyosarcoma

S
Sandeep Batra, MD
1 month - 21 years
All genders
Phase 3
Interventional
What is the purpose of this study?Rhabdomyosarcoma is a type of cancer that occurs in the soft tissues in the body. This phaseutcomes in patients with very low risk rhabdomyosarcoma (VLR-RMS) while decreasing the burden of therapy using treatment with 24 weeks of vincristined dactinomycin (VA) and examines the use …

The Gut Microbiome in Type 1 Diabetes and Mechanism of Metformin Action

H
Heba Ismail
11 years - 18 years
All genders
Phase 2
Interventional
Obesity prevalence in persons with T1D has increased, which further complicates managementd risk for complications. The proposed study is relevant to public health because it helps us understand the role of the gut microbiome in disease pathophysiology in T1D youth withbesity as well as potential mechanisms to modify disease.

Determinants of Incident Stroke Cognitive Outcomes and Vascular Effects on RecoverY (DISCOVERY)

J
Jason Mackey
18 years or above
All genders
Observational
The overall goal of the DISCOVERY study is to better understand what factors contribute tohanges in cognitive (i.e., thinking and memory) abilities in patients who experienced ake. The purpose of the study is to help doctors identify patients at risk for dementia (decline in memory, thinking and other mental abilities …

A Pilot Study in the Treatment of Refractory Epstein-Barr Virus (EBV) Infection with Related Donor EBV Cytotoxic T-Lymphocytes in Children, Adolescents and Young Adult Recipients - NYMC 581

S
Scott Goebel, MD
1 month - 79 years
All genders
Phase 2
Interventional
What is the purpose of this study?Related donor Epstein-Barr Virus (EBV) specific cytotoxic T cells (CTLs) manufactured withhe Miltenyi CliniMACS Prodigy Cytokine Capture System will be administered in children,dolescents and young adults with refractory EBV infection post Allogeneic Hematopoietic Stem Cell Transplantation (AlloHSCT), with primary immunodeficiencies (PID) or post solid …

Testicular Tissue Cryopreservation for Fertility Preservation

A
Amanda J. Saraf, DO
100 years or below
Male
Observational
What is the purpose of this study?Testicular tissue cryopreservation is an experimental procedure where a young boy's testicular tissue is retrieved and frozen. This technique is reserved for young male patients who are not yet producing mature sperm, with the ultimate goal that their tissue may be used in the …

An Observational Study of Carbaglu® for the Treatment of MMA and PA in Adults and Pediatrics

M
Melissa Lah, MD
All genders
Observational
To obtain short-term and long-term clinical safety information, in pediatric and adultwith PA and MMA treated with Carbaglu®.

Prospective Validation of a Points Score System Predicting 30-day Survival

N
Naoyuki Saito, MD
18 years or above
All genders
Phase 2
Observational
What is the purpose of this study?This is a one-stage single-arm phase II clinical trial designed to prospectively test the survival prediction tool as developed by Lee et al on patients referred to radiation oncologyve treatments. Survival prediction score based on objective data includingboratory values, attendance to emergency room, and …

Lamprene Multiple Patient Program

T
Tom F. Hrisomalos, MD
18 years or above
All genders
Lamprene®/Clofazimine, is a product of the pharmaceutical company named Novartis Pharmaceuticals Corporation. Lamprene®/Clofazimine is approved by FDA (the U.S Food and Drug Administration) for the treatment of leprosy. It is no longer available through pharmacies inhe US. It is being tested in non-Novartis clinical studies for drug resistant tuberculosisd non-tuberculous …

Expanded Access Program (EAP) for Ciltacabtagene Autoleucel (Cilta-Cel) Out-of-Specification (OOS) in Participants With Multiple Myeloma

R
Rafat Abonour, MD
18 years or above
All genders
What is the purpose of this study?The purpose of this expanded access program (EAP) is to provide ciltacabtagene autoleucel (cilta-cel) that does not meet the commercial release specifications of CARVYKTI and is notvailable via the local health care system in the country where the treatment is requested.THIS STUDY IS ENROLLING …

Evaluation of a New Strategy for Protocolized Antibiotic Care for Severe Open Fractures: SEXTANT

K
Karl Shively
L
Luke A. Lopas, MD
18 years - 64 years
All genders
Phase 3
Interventional
The proposed study is a multi-center, prospective randomized controlled trial comparingurrent standard of care treatment to the SEXTANT treatment protocol in patients with Typeures of the tibia and IIIB fractures of the ankle and hindfoot.
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