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Found 718 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Phase Ib Active Immunotherapy Trial (Expansion) with a Combination of Two Chimeric (Trastuzumab-like and Pertuzumab-like) HER-2 B Cell Peptide Vaccine emulsified in ISA 720 Adjuvant in Patients with Advanced Solid Tumors

K
Kathy Miller, MD
18 years - 100 years
All genders
Phase 1/2
What is the purpose of this study?This phase I trial studies the side effects and best dose of vaccine therapy in treating patients with metastatic solid tumors. Vaccines made from antibodies and peptides combined with tumor cells may help the body build an effective immune response to kill tumor cells.THIS …
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Immune Mechanisms of Hypertension and Cardiovascular Disease

Immune Mechanisms of Hypertension and Cardiovascular Disease

M
Meena Madhur
18 years - 85 years
Accepts healthy volunteer
All genders
Why is this study being done?The Division of Clinical Pharmacology at Indiana University is looking for volunteers with and without high blood pressure to participate in a research study to better understand how the immune system regulates blood pressure and cardiovascular disease.  This study will look at the differences in …
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Melanoma Margins Trial (MelMarT): A Phase III, multi-centre, multi-national randomised control trial investigating 1cm v 2cm wide excision margins for primary cutaneous melanoma

K
Karl Bilimoria
18 years - 100 years
All genders
Phase 3
What is the purpose of this study?Patients with a primary invasive melanoma are recommended to undergo excision of the primary lesion with a wide margin. There is evidence that less radical margins of excision may be just as safe. This is a randomised controlled trial of 1 cm versus 2 …
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Health Effects of Grain Food in Adults

R
Richard Mattes
18 years - 75 years
Accepts healthy volunteer
All genders
Why is this study being done?Researchers at Purdue University want to learn more about the health effects of eating whole grain foods vs. refined grain foods with different amounts of added sugar.  We hope that the knowledge gained from this study will provide new insights into dietary guidelines.  Who can take …
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Biomarkers for Noninvasive respiratory support in Immunocompromised Children (BioNIC)

C
Courtney Rowan, MD
1 years - 26 years
All genders
What is the purpose of this study?The goal of this study is to identify and validate response to therapy biomarkers for NIV respiratory support in children with ICCs. The central hypothesis is that response-to-therapy biomarkers can identify those most likely to benefit from intervention with NIV. The rationale is that …
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A Phase 3 Study of Dinutuximab Added to Intensive Multimodal Therapy for Children With Newly Diagnosed High-Risk Neuroblastoma

M
Marissa Just
1 years - 30 years
All genders
Phase 3
What is the purpose of this study?This phase III trial tests how well adding dinutuximab to induction chemotherapy along with standard of care surgery radiation and stem cell transplantation works for treating children with newly diagnosed high risk neuroblastoma. Dinutuximab is a monoclonal antibody that binds to a molecule called …
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GRONINGEN INTERNATIONAL STUDY ON SENTINEL NODES IN VULVAR CANCER III, A PROSPECTIVE PHASE II TREATMENT TRIAL

S
Sharon E. Robertson
18 years - 100 years
Female
Phase 2
What is the purpose of this study?The primary objective of this study is to investigate the safety of replacing inguinofemoral lymphadenectomy by chemoradiation in early stage vulvar cancer patients with a macrometastasis (>2mm) and/or extracapsular extension in the SN. The secondary objective is to evaluate the short and long-term morbidity …
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Maternal Brain Imaging in Opioid Use Disorder (BOOM Study)

Maternal Brain Imaging in Opioid Use Disorder (BOOM Study)

R
Rupa Radhakrishnan, MD
18 years - 100 years
Accepts healthy volunteer
Female
Why is this study being done?The purpose of this research study is to learn more about opioid use disorder (OUD) during pregnancy and how outcomes for pregnant women and their newborns can be improved. During pregnancy, people with OUD are prescribed medication-assisted therapy (MAT). We want to learn if this …
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An Investigator Sponsored Study to Investigate the Safety and Efficacy of CYTALUX (PAFOLACIANINE) INJECTION for the Intraoperative Imaging of Prostate Cancer

C
Clinton Bahler, MD
18 years - 100 years
Male
What is the purpose of this study?This is an open label trial in up to 15 subjects with biopsy confirmed prostate cancer (PCa) who have been scheduled to undergo a laparoscopic radical prostatectomy with or without robotic assistance, with pelvic lymph node dissection. This is a non-intervention trial to assess …
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Healthy Participants Needed for Magnesium Levels Research Study!

Healthy Participants Needed for Magnesium Levels Research Study!

N
Nana Gletsu Miller
18 years - 65 years
Accepts healthy volunteer
All genders
Why is this study being done?Researchers at Indiana University's School of Public Health are conducting a research study to establish a reference (or normal) range for magnesium levels in healthy adults. Your participation will help researchers find out what the normal levels of magnesium are and this data will help …
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