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Found 765 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

MODERN: An Integrated Phase 2/3 and Phase 3 Trial of MRD-Based Optimization of ADjuvant ThErapy in URothelial CaNcer

T
Tareq Salous
18 years - 100 years
All genders
Phase 2/3
What is this study about?This phase II/III trial examines whether patients who have undergone surgical removal of bladder, but require an additional treatment called immunotherapy to help prevent their bladder cancer from coming back, can be identified by a blood test. Many types of tumors tend to lose cells or …
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Immune Mechanisms of Hypertension and Cardiovascular Disease

Immune Mechanisms of Hypertension and Cardiovascular Disease

M
Meena Madhur
18 years - 85 years
Accepts healthy volunteer
All genders
Why is this study being done?The Division of Clinical Pharmacology at Indiana University is looking for volunteers with and without high blood pressure to participate in a research study to better understand how the immune system regulates blood pressure and cardiovascular disease.  This study will look at the differences in …
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Melanoma Margins Trial (MelMarT): A Phase III, multi-centre, multi-national randomised control trial investigating 1cm v 2cm wide excision margins for primary cutaneous melanoma

K
Karl Bilimoria
18 years - 100 years
All genders
Phase 3
What is the purpose of this study?Patients with a primary invasive melanoma are recommended to undergo excision of the primary lesion with a wide margin. There is evidence that less radical margins of excision may be just as safe. This is a randomised controlled trial of 1 cm versus 2 …
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Autoimmune Liver Disease Network for Kids (A-LiNK): Using Patient Data to Transform Care and Improve Outcomes for Children, Adolescents, and Young Adults With Autoimmune Liver Disease

K
Kyla Tolliver
1 years - 17 years
All genders
Observational
What is the purpose of this study?The Autoimmune Liver disease Network for Kids (A-LiNK) is a multi-institutional group with the mission to deliver the best care to kids with pediatric autoimmune liver disease (AILD).This study will establish a shared clinical registry and a learning health network for the participating sites …
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Health Effects of Grain Food in Adults

R
Richard Mattes
18 years - 75 years
Accepts healthy volunteer
All genders
Why is this study being done?Researchers at Purdue University want to learn more about the health effects of eating whole grain foods vs. refined grain foods with different amounts of added sugar.  We hope that the knowledge gained from this study will provide new insights into dietary guidelines.  Who can take …
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Biomarkers for Noninvasive respiratory support in Immunocompromised Children (BioNIC)

C
Courtney Rowan, MD
1 years - 26 years
All genders
What is the purpose of this study?The goal of this study is to identify and validate response to therapy biomarkers for NIV respiratory support in children with ICCs. The central hypothesis is that response-to-therapy biomarkers can identify those most likely to benefit from intervention with NIV. The rationale is that …
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A Phase 3 Study of Dinutuximab Added to Intensive Multimodal Therapy for Children With Newly Diagnosed High-Risk Neuroblastoma

M
Marissa Just
1 years - 30 years
All genders
Phase 3
What is the purpose of this study?This phase III trial tests how well adding dinutuximab to induction chemotherapy along with standard of care surgery radiation and stem cell transplantation works for treating children with newly diagnosed high risk neuroblastoma. Dinutuximab is a monoclonal antibody that binds to a molecule called …
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GRONINGEN INTERNATIONAL STUDY ON SENTINEL NODES IN VULVAR CANCER III, A PROSPECTIVE PHASE II TREATMENT TRIAL

S
Sharon E. Robertson
18 years - 100 years
Female
Phase 2
What is the purpose of this study?The primary objective of this study is to investigate the safety of replacing inguinofemoral lymphadenectomy by chemoradiation in early stage vulvar cancer patients with a macrometastasis (>2mm) and/or extracapsular extension in the SN. The secondary objective is to evaluate the short and long-term morbidity …
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Microbiome alterations in the setting of intestinal failure associated liver disease

K
Katie Huff
18 months or below
All genders
What is the purpose of this study?Neonates who require prolonged IV nutrition (TPN) are at risk for such complications as intestinal failure associated liver disease (IFALD). In addition, it is also known that TPN and lack of nutrition through the GI tract influences the intestinal microbiome or bacteria present in …
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Maternal Brain Imaging in Opioid Use Disorder (BOOM Study)

Maternal Brain Imaging in Opioid Use Disorder (BOOM Study)

R
Rupa Radhakrishnan, MD
18 years - 100 years
Accepts healthy volunteer
Female
Why is this study being done?The purpose of this research study is to learn more about opioid use disorder (OUD) during pregnancy and how outcomes for pregnant women and their newborns can be improved. During pregnancy, people with OUD are prescribed medication-assisted therapy (MAT). We want to learn if this …
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