Found 743 results
A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Registry of Patients With Brain Tumors Treated With STaRT (GammaTiles)
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Mitesh Shah, MD
What is the purpose of this study?The objectives of this registry study are to evaluate real-world clinical outcomes andd outcomes that measure the effectiveness and safety of STaRT.THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with most oncology trials, patients are not actively “recruited,” but are screened by their …
Prevalence and Predictors of Hepatic Steatosis in Persons Living With HIV
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Naga Chalasani, MD
Nonalcoholic fatty liver disease (NAFLD) is a spectrum of liver conditions associated withumulation that ranges from benign, non-progressive liver fat accumulation to severever injury, cirrhosis, and liver failure. NAFLD is the most common liver disease in USdults and the second leading cause for liver transplantation in the US. The natural …
Trastuzumab Deruxtecan for the Treatment of HER2+ Newly Diagnosed or Recurrent Osteosarcoma
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Brian Weiss
This phase II trial studies the effects of trastuzumab deruxtecan in treating patients with HER2 positive osteosarcoma that is newly diagnosed or has come back (recurrent). Trastuzumab deruxtecan is a monoclonal antibody, called trastuzumab, linked to a chemotherapy drug called deruxtecan. Trastuzumab attaches to HER2 positive cancer cells in a …
A Study of Combination Chemotherapy for Patients With Newly Diagnosed DAWT and Relapsed FHWT
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Marissa Just
What is the purpose of this study?This phase II trial studies how well combination chemotherapy works in treating patients withwly diagnosed stage II-IV diffuse anaplastic Wilms tumors (DAWT) or favorable histology Wilms tumors (FHWT) that have come back (relapsed). Drugs used in chemotherapy regimens suchH-3 (vincristine, doxorubicin, cyclophosphamide, carboplatin, etoposide, …
Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS) (POPS or POP02)
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Gregory Sokol, MD
The study investigators are interested in learning more about how drugs, that are given tohildren by their health care provider, act in the bodies of children and young adults in hopes to find the most safe and effective dose for children. The primary objective of thisudy is to evaluate the …
Volunteers Needed for Long COVID Tracking Study
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Shaun Grannis, MD
Why is this study being done?Indiana University with the Centers for Disease Control and Prevention (CDC) is running a study on long COVID. Post-COVID conditions (PCC) are impacting many Americans across all agesd demographics, but very little is known yet about how many, and the severity of people impacted. We …
A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations
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Sandeep Batra, MD
What is the purpose of this study?This phase III trial compares standard chemotherapy to therapy with liposome-encapsulated daunorubicin-cytarabine (CPX-351) and/or gilteritinib for patients with newly diagnosed acuteyeloid leukemia with or without FLT3 mutations. Drugs used in chemotherapy, such as daunorubicin, cytarabine, and gemtuzumab ozogamicin, work in different ways to stop …
A Phase 3 Randomized Non-Inferiority Study of Carboplatin and Vincristine versus Selumetinib in Newly Diagnosed or Previously Untreated Low-Grade Glioma (LGG) not associated with BRAFV600E Mutations or Systemic Neurofibromatosis Type 1 (NF1)
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Sandeep Batra, MD
This phase III trial compares the effect of selumetinib versus the standard of care treatment with carboplatin and vincristine (CV) in treating patients with newly diagnosed or previously untreated low-grade glioma (LGG) that does not have a genetic abnormality called BRAFV600Eutation and is not associated with systemic neurofibromatosis type 1. …
Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy
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Sandeep Batra, MD
This phase III trial studies whether inotuzumab ozogamicin added to post-induction chemotherapy for patients with High-Risk B-cell Acute Lymphoblastic Leukemia (B-ALL) improves outcomes. This trial also studies the outcomes of patients with mixed phenotype acute leukemia (MPAL), and B-lymphoblastic lymphoma (B-LLy) when treated with ALL therapy without inotuzumab ozogamicin. Inotuzumab …
Filgotinib in Long-Term Extension Study of Adults With Crohn's Disease (DIVERSITYLTE)
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Matthew Bohm, DO
The primary objective of this study is to observe the long-term safety of filgotinib indults who have completed or met protocol specified efficacy discontinuation criteria in agotinib treatment study in Crohn's disease (CD).
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