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Found 716 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

OPTIMICE-PCR: DE-ESCALATION OF THERAPY IN EARLY-STAGE TNBC PATIENTS WHO ACHIEVE PCR AFTER NEOADJUVANT CHEMOTHERAPY WITH CHECKPOINT INHIBITOR THERAPY

N
Nawal Kassem
18-100 years
All genders
Phase 3
What is the purpose of this study?The phase III trial compares the effect of pembrolizumab to observation for the treatment of patients with early-stage triple-negative breast cancer who achieved a pathologic complete response after preoperative chemotherapy in combination with pembrolizumab. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the …
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Vitamin D Genetics and Racial Differences in Pediatric Chronic Kidney Disease-Mineral and Bone Disorder

M
Marciana Laster
6-21 years
All genders
Observational
What is this study about?We will look at genetic biomarkers to explore potential racial differences that could inform the treatment of bone disease in children (under age 21) with kidney disease. THIS STUDY IS ENROLLING BY INVITATION ONLY - Potential participants will be approached by a research team member who …
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Isolating PAECs

M
Micheala Aldred
18-89 years
All genders
The primary outcome measure will be the success rates of isolating PAECs from PACs and comparing between the different methods (balloon tip versus aspirated blood), between PH subtypes, and then PH patients and control patients using demographic and objective data obtained from our cohort.
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Analysis of Senescent Markers in Periodontal and Periimplant Tissue

C
Chandni Batra
18-100 years
All genders
The aim of our study is 1) to analyze the level of senescence markers in periodontally healthy and diseased gingival tissue;2) to analyze the level of senescence markers in periodontal and periimplant diseased gingival tissues and reveal the association between cellular senescence or ageing on progression of periodontal disease and …
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Assessment of barriers to clubfoot treatment in the state of Indiana

R
Robert Bielski
100 years and younger
All genders
Investigate the various barriers that affect adherence to the Ponseti method for clubfoot treatment in the state of IndianaTo assess the impact of these barriers on the rate of missed or discontinued clinic visits within the first three months of treatment
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Clinical factors affecting renal recovery in pediatric critical illness.

D
Daniel Cater
28-17 years
All genders
This is an observational prospective study and a retrospective study. For the prospective study, the clinical data and blood sample will be collected in accordance with standard procedure currently used in patient care at our institutions. For the retrospective study, patients requiring acute dialysis in the pediatric ICU and CVICU …
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Pilot Pharmacokinetic Study of VAL-413 (Orotecan) in Patients with Recurrent Pediatric Solid Tumors

K
Kyle William Jackson
1-30 years
All genders
Phase 2
What is the purpose of this study?To establish the recommended phase II dose of a flavored preparation of orally administered irinotecan (VAL-413) when given in combination with temozolomide for five consecutive days. To characterize and compare the pharmacokinetic profiles of VAL-413 and conventional irinotecan given orally To evaluate the palatability …
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Household Material Hardship

S
Scott Coven
21 years and younger
All genders
This proposal will expand on our current work with the SRC/IRB approved project (IRB: #15991 Assessing Household Material Hardship in Children with Central Nervous System (CNS) Tumors). This new population can serve as a comparison, with children admitted to the hospital for infectious diseases and requiring long hospital stays and/or …
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Abbott Neonate i-STAT

T
Thomas E. Davis
28 years and younger
All genders
Compare the performance of the tests on the i-STAT CG4+ and CG8+ cartridges on the iSTAT 1 analyzer to the performance of the tests on the comparator device, the RAPIDPoint® 500e System or epoc® Blood Analysis System using neonatal capillary whole blood specimens
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Sympathetic Nerve Activity and Cardiovascular Events.

T
Thomas Everett
18-100 years
Accepts healthy volunteer
All genders
The purpose of this study is to test the hypothesis that skin sympathetic nerve activity (SKNA) can be used as a biomarker for physiological events including predicting neurological recovery during therapeutic hypothermia for cardiac arrest, and to risk stratify patients for recurrence of atrial fibrillation (AF) following catheter ablation.
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