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Found 760 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Determinants of Incident Stroke Cognitive Outcomes and Vascular Effects on RecoverY (DISCOVERY)

J
Jason Mackey
18 years or above
All genders
Observational
The overall goal of the DISCOVERY study is to better understand what factors contribute tohanges in cognitive (i.e., thinking and memory) abilities in patients who experienced ake. The purpose of the study is to help doctors identify patients at risk for dementia (decline in memory, thinking and other mental abilities …
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An Observational Study of Carbaglu® for the Treatment of MMA and PA in Adults and Pediatrics

M
Melissa Lah, MD
All genders
Observational
To obtain short-term and long-term clinical safety information, in pediatric and adultwith PA and MMA treated with Carbaglu®.
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TReatment for ImmUne Mediated PathopHysiology (TRIUMPH)

J
Jean Molleston, MD
1 year - 18 years
All genders
Phase 2
Interventional
TReatment for ImmUne Mediated PathopHysiology (TRIUMPH) is a multi-center, three arm,domized, controlled trial of immunosuppressive therapy for children with acute liverure. The study will determine if suppressing inflammatory responses with eitherds or equine anti-thymocyte globulin therapy improves survival for children withhis rare, life-threatening condition.
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Investigation of an Investigational Medication for Drug-Resistant Mycobacterial Infections

T
Tom F. Hrisomalos, MD
18 years or above
All genders
This study investigates the use of clofazimine, an investigational medication, for patients with drug-resistant non-tuberculous mycobacteria (NTM) infections. NTM infections occur when bacteria from the environment cause illness in people. Clofazimine is usually used to treat leprosy but is being tested here for its effectiveness against NTM, especially in cases …
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Evaluation of a New Strategy for Protocolized Antibiotic Care for Severe Open Fractures: SEXTANT

K
Karl Shively
L
Luke A. Lopas, MD
18 years - 64 years
All genders
Phase 3
Interventional
The proposed study is a multi-center, prospective randomized controlled trial comparingurrent standard of care treatment to the SEXTANT treatment protocol in patients with Typeures of the tibia and IIIB fractures of the ankle and hindfoot.
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Effect of NSAIDs on Union, Opioid Utilization and Pain Management for Tibia Fractures

K
Karl Shively
B
Brian Mullis, MD
18 years - 80 years
All genders
Phase 3
Interventional
The proposed study is a two arm, pragmatic, randomized controlled multicenter Phase IIIy trial. 1,000 patients with tibia fractures treated with intramedullary (IM)will be randomized into two treatment arms. The control arm will receive standard paingement and no NSAIDs. The treatment arm will receive standard pain management plus up toweeks …
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A Phase 2 Trial of Chemotherapy followed by Response-Based Whole Ventricular & Spinal Canal Irradiation (WVSCI) for Patients with Localized Non-Germinomatous Central Nervous System Germ Cell Tumor.

S
Sandeep Batra, MD
3 years - 30 years
All genders
Phase 2
Interventional
What is the purpose of this study?This phase II trial studies the best approach to combine chemotherapy and radiation therapy (RT) based on the patient's response to induction chemotherapy in patients withgerminomatous germ cell tumors (NGGCT) that have not spread to other parts of the brainbody (localized). This study has …
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Intensive Glycemic Targets in Overweight and Obese Women With Gestational Diabetes (iGDM)

C
Christina M. Scifres, MD
18 years - 45 years
Female
Interventional
This is a multicenter randomized clinical trial of 828 overweight and obese individuals with gestational diabetes designed to compare standard to intensive glycemic targets.
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Biomarker of Diabetic Retinopathy

A
Ashay D. Bhatwadekar, PhD, MPHARM
18 years or above
All genders
Observational
What is the purpose of this study?Diabetic retinopathy is characterized by damage to retinal blood vessels. At present, there is no diagnostic marker reflecting retinal vascular health. By studying RNA content (genetic material that makes proteins) in highly specialized cells in circulating blood resembling blood vessels, we will discover biomarker …
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ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)

D
David Clark
18 years or above
Accepts healthy volunteer
All genders
ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD) represents thezed integration of ARTFL (U54 NS092089; funded through 2019) and LEFFTDS (U01 AG045390; funded through 2019) as a single North American research consortium to study FTLD2019 and beyond.
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