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Found 760 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Oral Ifetroban in Subjects With Duchenne Muscular Dystrophy (DMD)

J
John Parent, MD
7 years or above
Male
Phase 2
Interventional
What is the purpose of this study?Duchenne muscular dystrophy (DMD) is a devastating X-linked disease which leads to loss ofbulation between ages 7 and 13, respiratory failure and cardiomyopathy (CM) at any age, an dvitably premature death of affected young men in their late twenties. DMD is the mostgenetic disorder …
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A Study to Assess the Long-Term Safety and Efficacy of Eplontersen (Formerly Known as ION-682884, IONIS-TTR-LRx and AKCEA-TTR-LRx) in Patients With Hereditary Transthyretin-Mediated Amyloid Polyneuropathy

N
Noel Dasgupta
18 years or above
All genders
Phase 3
Interventional
The purpose of this study is to evaluate the safety and tolerability of extended dosing withwith hereditary transthyretin-mediated amyloid polyneuropathy (hATTR-PN).
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Prevalence and Predictors of Hepatic Steatosis in Persons Living With HIV

N
Naga Chalasani, MD
18 years - 80 years
All genders
Observational
Nonalcoholic fatty liver disease (NAFLD) is a spectrum of liver conditions associated withumulation that ranges from benign, non-progressive liver fat accumulation to severever injury, cirrhosis, and liver failure. NAFLD is the most common liver disease in USdults and the second leading cause for liver transplantation in the US. The natural …
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Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS) (POPS or POP02)

G
Gregory Sokol, MD
20 years or below
Accepts healthy volunteer
All genders
The study investigators are interested in learning more about how drugs, that are given tohildren by their health care provider, act in the bodies of children and young adults in hopes to find the most safe and effective dose for children. The primary objective of thisudy is to evaluate the …
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Improving the Quality of Care for Adults With Inflammatory Bowel Disease (IBD:QORUS)

S
Sashidhar Sagi, MD
18 years or above
All genders
Observational
Innovative programs exist that suggest that care for people with chronic conditions iszed when patients and providers have the information they need at the point of care andver time, to engage in shared planning and execution of treatment goals and care plans. Thisject aims to build an Inflammatory Bowel Disease …
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Investigating CD4CAR T Cell Therapy for Chronic Myelomonocytic Leukemia

H
Huda Salman
18 years - 100 years
All genders
This study investigates the safety and effectiveness of CD4CAR T cell therapy for patients with relapsed or refractory CD4+ chronic myelomonocytic leukemia (CMML). CMML is a type of blood cancer that affects white blood cells, which have a protein called CD4. The CD4CAR T cell therapy is designed to target …
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Investigating Tolerability of Combined Radiation Treatments for Prostate Cancer

O
Omar Ishaq
18 years - 100 years
Male
This study investigates the tolerability and side effects of combining two types of radiation therapy for prostate cancer. The first is Elective Pelvic Ultra Hypofractionated Irradiation Treatment (ePUHRT), which is a type of external beam radiotherapy. The second is High Dose Rate Brachytherapy Boost, a form of internal radiation where …
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A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations

S
Sandeep Batra, MD
21 years or below
All genders
Phase 3
Interventional
What is the purpose of this study?This phase III trial compares standard chemotherapy to therapy with liposome-encapsulated daunorubicin-cytarabine (CPX-351) and/or gilteritinib for patients with newly diagnosed acuteyeloid leukemia with or without FLT3 mutations. Drugs used in chemotherapy, such as daunorubicin, cytarabine, and gemtuzumab ozogamicin, work in different ways to stop …
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Study of Investigational Treatment for Slow-Growing Brain Tumors in Children and Young Adults

S
Sandeep Batra, MD
2 years - 21 years
All genders
Phase 3
Interventional
This study investigates treatment options for children and young adults with low-grade glioma (LGG), a type of brain tumor. The purpose of this study is to compare the effects of an investigational medication with standard chemotherapy treatments, carboplatin and vincristine, in patients who do not have a specific genetic mutation …
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Study on Adding an Investigational Medication to Chemotherapy for High-Risk Leukemia

S
Sandeep Batra, MD
1 year - 25 years
All genders
Phase 3
Interventional
This study investigates the effectiveness of adding an investigational medication to post-induction chemotherapy for patients with High-Risk B-cell Acute Lymphoblastic Leukemia (B-ALL). It also examines outcomes for patients with mixed phenotype acute leukemia (MPAL) and B-lymphoblastic lymphoma (B-LLy) treated with standard chemotherapy. B-ALL is a type of cancer that affects …
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