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Found 743 results
A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Non-invasive Pressure Monitor for Neonates and Infants at Risk of Developing Hydrocephalus
J
Jignesh Tailor
The purpose of this study is to test a device designed to monitor pressure within the skull of neonates and infants at risk of developing hydrocephalus (fluid and pressure build-up in the brain). The device will measure changes in the anterior fontanelle (soft spot). The study will be conducted in …
Defining the Pathobiology of Coarctation of the Aorta
B
Benjamin Landis, MD
What is this study about?Coarctation of the aorta (CoA) tissues contain distinctive cell populations, and comprehensive analysis of these cells will provide understanding of cell abnormalities that are driving CoA. We want to define these types of cells that are abnormally located in the diseased aortic tissues of neonates with …
The Resilience Songwriting Program for Adolescent Bereavement
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Jayme Allen, MD
Experiencing the death of a loved one is hard. We want to understand how a songwriting program can impact grief and resiliency in teens who have experienced the loss of aloved one. The purpose of this study is to learn more about how a songwriting program may affect grief and …
A Randomized, Double-Blind, Placebo-Controlled Phase II Study to Determine the Safety and Efficacy of Oral Ifetroban in Patients With Idiopathic Pulmonary Fibrosis (IPF)
D
Damien G. Patel, MD
What is the goal of this study?Ifetroban prevents and treats lung fibrosis due to multiple causes (bleomycin, genetic, radiation). The purpose of this study is to determine the safety and efficacy of oral ifetroban compared to placebo in subjects with IPF. THIS STUDY IS ENROLLING BY INVITATION ONLY
Testing Health-Related Interventions: Voices of Equity Needed to Overcome Weight-bias in Obesity-Cancer Care THRIVE NOW in Obesity-Cancer Care
M
Misty Hawkins
There are long-standing inequities in interventions for obesity among Black Breast Cancer Survivors (BCS). While the American Cancer Society provides recommendations regarding weight management for successful cancer survivorship, the guidelines are not specific to women or Blacks. This 3-phase pilot study will address these inequities by inviting Black BCS with …
A Long-term Multicenter Prospective Observational Study Evaluating the Comparative Effectiveness and Safety of Sarepta Gene Transfer Therapy vs. Standard of Care in Participants with Duchenne Muscular Dystrophy under Conditions of Routine Clinical Practice
M
Marcia Felker, MD
What is the purpose of this study?This is a multicenter, prospective, observational Phase 4 study in the United States. The study is designed to collect both medical history and prospective data on Duchenne muscular dystrophy (DMD) treatment outcomes in participants receiving delandistrogene moxeparvovec as part of clinical care, compared to …
Placental Chorangioma Prospective Observational Study
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David Streitman, MD
Placental chorangioma is a rare pregnancy complication but with significant maternal and fetal consequences. Chorangioma is a benign tumor of the placenta. As it grows, it can cause pregnancy complications. Little is known about the natural history of placental chorangioma or its response to in-utero intervention. The aim of this …
Multi-Institutional Cohort Study of a Non-invasive Technique for Bedside Reduction of Giant Omphaloceles
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Matthew Landman, MD
WHY IS THIS STUDY BEING DONE?The main reason for this research study is to understand what happens with patients who are treated for giant omphaloceles (GO) using a non-invasive staged closure technique that uses a hydrocolloid (Duoderm CGF) silo. Omphaloceles are a rare (birth) defect where infants are born with …
A Randomized, Open-label, Multicentric, Two-arm Pivotal Trial of SonoCloud-9 Combined With Carboplatin (CBDCA) vs Standard of Care Lomustine (CCNU) or Temozolomide (TMZ) in Patients Undergoing Planned Resection for First Recurrence Glioblastoma.
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Kathryn Nevel
What is the purpose of this study?The brain is protected from any toxic or inflammatory molecule by the blood-brain barrier (BBB). This physical barrier is located at the level of the blood vessel walls. Because of these barrier properties, the blood vessels are also impermeable to the passage of therapeutic …
Evaluation of the GORE® Ascending Stent Graft in the Treatment of Lesions of the Ascending Aorta
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Joel Corvera, MD
What is this study about?The primary objective of ARISE II is to assess the safety and effectiveness of the GORE® Ascending Stent Graft device in the treatment of lesions involving the ascending aorta and aortic arch. THIS STUDY IS ENROLLING BY INVITATION ONLY
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