Found 740 results
A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Latine Teens 13-17 and Their Caregivers Needed for Research Study
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Matthew Aalsma
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Natalie Guerrero
Why is this study being done?Caregiver support is important for adolescent mental health and may help young people manage the negative impacts of difficult experiences, such as racial-ethnic discrimination. We hope to learn more about how caregivers support their adolescents and use the information gained from this study to create …
A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study to Evaluate the Safety and Efficacy of Fazirsiran in the Treatment of Alpha-1 Antitrypsin Deficiency-Associated Liver Disease With METAVIR Stage F1 Fibrosis
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Raj Vuppalanchi, MD
Why is this study being done?In some people, the liver makes an abnormal version of the alpha-1 antitrypsin (AAT) protein, called Z-AAT. Making an abnormal version of the AAT protein can result in liver disease as Z-AAT builds up in liver cells, which leads to liver problems such as liver …
IMPRoving Outcomes in Vascular DisEase- Aortic Dissection
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Raghu Motaganahalli, MD
Why is this study being done?The study will be a prospective, pragmatic, randomized clinical trial ofhe comparative effectiveness of an initial strategy for the treatment of uncomplicated type B aortic dissection (uTBAD). The goal of this clinical trial is to determine whether an upfront invasive strategy of TEVAR plus medical …
A Master Protocol of Randomized, Double-Blind, Placebo-Controlled, Phase 2 Studies of siRNA Gene Silencing for the Treatment of Non- Alcoholic Steatohepatitis (NASH) in Participants With Genetic Risk Factors
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Niharika Samala, MD
The study is researching an investigational drug called ALN-HSD (called "study drug" in this form). The study is focused on participants who are known to have non-alcoholic steatohepatitis (NASH). NASH is a form of non-alcoholic fatty liver disease (NAFLD). NASH occurs when fat builds up in liver cells, damaging them, …
Positron Emission Tomography Using 64Cu-SAR-bisPSMA in Participants With High-risk Prostate Cancer Prior to Radical Prostatectomy: A Prospective, Single-arm, Multi-center, Blinded-review, Phase 3 Diagnostic Performance Study
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Clinton Bahler, MD
What is the purpose of this study?The aim for this study is to assess the diagnostic performance of 64Cu-SAR-bisPSMA PET to detect regional nodal metastases. THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with most oncology trials, patients are not actively “recruited,” but are screened by their physician for appropriate …
Functional Assessment in Liver Transplantation (FrAILT) Study; Functional Assessment in Liver Transplant Candidates (FrAILT) Study
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Marwan Ghabril
This will be a prospective cohort study of patients with liver disease. Subjects will undergo geriatric assessments of frailty, functional status, and disability using functional status measures at baseline and at every clinic visit in the pre-transplant setting. Subjects will also answer questions regarding quality of life, personality, and/or cognitive …
A Protocol for Children and Young Adults Diagnosed with a Central Nervous System (CNS) Tumor to Assess Cognitive, Quality of Life (QOL), and Comprehensive Effects of Therapies
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Scott Coven
What is the purpose of this study?To longitudinally assess cognitive outcomes using an a neurocognitive screening battery in children and young adults diagnosed with a CNS tumor. To longitudinally assess the impact of specific therapies on the QOL in children and young adults diagnosed with a CNS tumor.To longitudinally assess …
The ADRC Consortium for Clarity in ADRD Research Through Imaging (CLARITI)
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Shannon Risacher
This study seeks to identify the several possible causes of dementia that may be present in an individual, and that may be contributing to a person’s current or future cognitive symptoms. The study will run a panel of experimental and established biomarker tests for the several causes of dementia such …
A Phase 1b/2 Trial of Targeted Immunotherapy with Daratumumab Following Myeloablative Total Body Irradiation (TBI)-Based Conditioning and Allogeneic Hematopoietic Cell Transplantation in Children, Adolescents and Young Adults with High-Risk T-Cell Acute Lymphoblastic Leukemia and Lymphoma
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Jodi Skiles
A Phase 1b/2 trial to determine the safety of targeted immunotherapy with daratumumab (DARA) IV after total body irradiation (TBI)-based myeloablative conditioning and allogeneic hematopoietic cell transplantation (HCT) for children, adolescents, and young adults (CAYA) with high risk T-cell acute lymphoblastic leukemia (T-ALL) or T-cell lymphoblastic lymphoma (T-LLy). THIS STUDY IS …
Quality Technical Agreement for Thymus Fragments collection
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Jeremy Herrmann, MD
What is the purpose of this study?SANOFI Genzyme collects thymus fragments from pediatric cardiothoracic centers. These thymus fragments are used for the extraction of thymocytes to manufacture the medicine named Thymoglobuline. This medication is used in organ transplantation and in hematological disorders. THIS STUDY IS ENROLLING BY INVITATION ONLY - Subjects …
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