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Found 748 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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A Randomized, Open-label, Multicentric, Two-arm Pivotal Trial of SonoCloud-9 Combined With Carboplatin (CBDCA) vs Standard of Care Lomustine (CCNU) or Temozolomide (TMZ) in Patients Undergoing Planned Resection for First Recurrence Glioblastoma.

K
Kathryn Nevel
18 years - 100 years
All genders
Phase 3
What is the purpose of this study?The brain is protected from any toxic or inflammatory molecule by the blood-brain barrier (BBB). This physical barrier is located at the level of the blood vessel walls. Because of these barrier properties, the blood vessels are also impermeable to the passage of therapeutic …
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Evaluation of the GORE® Ascending Stent Graft in the Treatment of Lesions of the Ascending Aorta

J
Joel Corvera, MD
18 years - 100 years
All genders
Interventional
What is this study about?The primary objective of ARISE II is to assess the safety and effectiveness of the GORE® Ascending Stent Graft device in the treatment of lesions involving the ascending aorta and aortic arch. THIS STUDY IS ENROLLING BY INVITATION ONLY
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Measuring Spiritual Distress in Expectant Parents with Cleft Lip and/or Cleft Palate Diagnosis

K
Katelyn Makar
18 years - 100 years
All genders
Observational
Diagnosis of cleft lip and/or cleft palate (CLP) can be made using ultrasound. This diagnosis can be a shock for both parents, especially the expecting mother, and can cause spiritual distress. We are asking parents who are expecting a baby with cleft diagnosis to complete a survey about spiritual distress …
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Reactions Event Appraisals and Context in TBI

F
Flora Hammond, MD
18 years - 100 years
All genders
Observational
What is this study about?Our primary objective is to provide new knowledge to better understand angry and aggressive reactions that persons with chronic traumatic brain injury (TBI) experience in response to events in their daily lives. This will be accomplished by examining the patterns of occurrence of angry and aggressive …
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AIHA Patient Registry

C
Craig Lammert, MD
100 years or below
All genders
WHY IS THIS STUDY BEING DONE?Autoimmune hepatitis (AIH) is liver inflammation that occurs when the body’s immune system attacks liver cells. It is caused by an overactive immune system, and it is unknown why this happens. The Autoimmune Hepatitis Association (AIHA) is a not-for-profit organization seeking to develop a patient …
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Investigational Medicine to Stop Tumor Growth in Kids with NF1

S
Steven Rhodes
1 years - 8 years
All genders
Phase 2
This study investigates the use of an investigational medication to prevent the growth of plexiform neurofibromas in children with Neurofibromatosis Type 1 (NF1). NF1 is a genetic disorder that often causes tumors to grow on nerve tissues, which can lead to various health problems. The study aims to see if …
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Latine Teens 13-17 and Their Caregivers Needed for Research Study

Latine Teens 13-17 and Their Caregivers Needed for Research Study

M
Matthew Aalsma
N
Natalie Guerrero
13 years - 17 years
Accepts healthy volunteer
All genders
Why is this study being done?Caregiver support is important for adolescent mental health and may help young people manage the negative impacts of difficult experiences, such as racial-ethnic discrimination. We hope to learn more about how caregivers support their adolescents and use the information gained from this study to create …
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Online study

A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study to Evaluate the Safety and Efficacy of Fazirsiran in the Treatment of Alpha-1 Antitrypsin Deficiency-Associated Liver Disease With METAVIR Stage F1 Fibrosis

R
Raj Vuppalanchi, MD
18 years - 75 years
All genders
Phase 3
Interventional
Why is this study being done?In some people, the liver makes an abnormal version of the alpha-1 antitrypsin (AAT) protein, called Z-AAT. Making an abnormal version of the AAT protein can result in liver disease as Z-AAT builds up in liver cells, which leads to liver problems such as liver …
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IMPRoving Outcomes in Vascular DisEase- Aortic Dissection

R
Raghu Motaganahalli, MD
21 years - 100 years
All genders
Interventional
Why is this study being done?The study will be a prospective, pragmatic, randomized clinical trial ofhe comparative effectiveness of an initial strategy for the treatment of uncomplicated type B aortic dissection (uTBAD). The goal of this clinical trial is to determine whether an upfront invasive strategy of TEVAR plus medical …
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Study of Investigational Treatment for Non-Alcoholic Steatohepatitis (NASH)

N
Niharika Samala, MD
18 years - 75 years
All genders
Phase 2
Interventional
This study investigates a treatment for Non-Alcoholic Steatohepatitis (NASH), a liver condition where fat builds up in the liver, causing damage and inflammation. This can lead to scarring and liver failure. The purpose of this study is to evaluate how an investigational medication affects liver scarring in people with NASH.Participants …
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