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Found 741 results
A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Quality Technical Agreement for Thymus Fragments collection
J
Jeremy Herrmann, MD
What is the purpose of this study?SANOFI Genzyme collects thymus fragments from pediatric cardiothoracic centers. These thymus fragments are used for the extraction of thymocytes to manufacture the medicine named Thymoglobuline. This medication is used in organ transplantation and in hematological disorders. THIS STUDY IS ENROLLING BY INVITATION ONLY - Subjects …
Autoimmune Liver Disease Network for Kids (A-LiNK): Using Patient Data to Transform Care and Improve Outcomes for Children, Adolescents, and Young Adults With Autoimmune Liver Disease
K
Kyla Tolliver
What is the purpose of this study?The Autoimmune Liver disease Network for Kids (A-LiNK) is a multi-institutional group with the mission to deliver the best care to kids with pediatric autoimmune liver disease (AILD).This study will establish a shared clinical registry and a learning health network for the participating sites …
Biomarkers for Noninvasive respiratory support in Immunocompromised Children (BioNIC)
C
Courtney Rowan, MD
What is the purpose of this study?The goal of this study is to identify and validate response to therapy biomarkers for NIV respiratory support in children with ICCs. The central hypothesis is that response-to-therapy biomarkers can identify those most likely to benefit from intervention with NIV. The rationale is that …
Monitoring Volatile Organic Compound Profiles in Exhaled Breath to Noninvasively Detect Glycemic Events in Patients with Diabetes
M
Mangilal Agarwal
Scosche Industries, Inc. has developed a completely noninvasive device which detects exhaled volatile organic compound (VOC) biomarkers. This wearable device was designed with the goal of early detection of hyperglycemia and possibly hypoglycemia in patients with diabetes. At this time, the device can be worn on the body (e.g. on …
A Phase 3, Double-Blind, Randomized, Placebo-Controlled Study of Levosimendan in Pulmonary Hypertension Patients With Heart Failure With Preserved Left Ventricular Ejection Fraction (PH-HFpEF)
A
Ankit Desai
What is the purpose of this study?The study will evaluate the efficacy and safety of chronic oral levosimendan compared with placebo in PH-HFpEF subjects. This subject population represents a large and growing group with no established therapies to treat their PVD and RV dysfunction. Levosimendan and its prolonged active metabolite, …
A Real-World Comparative Effectiveness Trial Of Treatment Strategies In Patients With Rheumatoid Arthritis: The RA-PRO (Patient-Reported Outcomes) Pragmatic Trial (RA-PROPR)
S
Sneha Pai
What is the purpose of this study?The purpose of the study is to assess whether replacing their current TNF-biologic with a non-TNF-biologic is superior to adding a targeted synthetic DMARD (disease-modifying anti-rheumatic) medication with active RA despite current TNF-biologic treatment. THIS STUDY IS ENROLLING BY INVITATION ONLY - Patients who have …
Equity Using Interventions for Pain and Depression (EQUIPD) - Phase 2
M
Marianne Matthias
What is the purpose of this study?This is phase 2 of a two-phase project with the overarching goal of testing a decision aid paired with coaching sessions, tailored to Black patients with comorbid chronic pain and depression. The decision aid/coaching sessions are designed to help people learn more about other …
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A Phase 3 Study of Dinutuximab Added to Intensive Multimodal Therapy for Children With Newly Diagnosed High-Risk Neuroblastoma
M
Marissa Just
This phase III trial tests how well adding dinutuximab to induction chemotherapy along with standard of care surgery radiation and stem cell transplantation works for treating children with newly diagnosed high risk neuroblastoma. Dinutuximab is a monoclonal antibody that binds to a molecule called GD2, which is found in greater …
Microbiome alterations in the setting of intestinal failure associated liver disease
K
Katie Huff
What is the purpose of this study?Neonates who require prolonged IV nutrition (TPN) are at risk for such complications as intestinal failure associated liver disease (IFALD). In addition, it is also known that TPN and lack of nutrition through the GI tract influences the intestinal microbiome or bacteria present in …
Detection of late subclinical cardiovascular disease in testicular cancer survivors exposed to cisplatin chemotherapy and bone marrow transplant
N
Nabil Adra, MD
Testicular cancer (TC) is diagnosed in young adult males between ages 18-39 and TC treatment involves the use of platinum therapy (CBCT) which can have long-term cardiovascular effects. We are looking at cholesterol and hormone changes, as well as blood vessel changes for coronary artery disease or blockages in the …
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