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Found 743 results
A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Investigation of Intracranial Pressure Dynamics in Glaucoma: An Innovative Approach
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Tasneem Putiwala Sharma
What is the purpose of this study?We propose using optic ultrasonography to measure optic nerve sheath diameter, as an indicator of intracranial pressure, within the glaucoma population at the Ophthalmology health clinics at Indiana University School of Medicine (Eugene and Marilyn Glick Eye Institute and Spring Mill clinic) to determine …
HPP and Ehlers-Danlos Syndrome: Clinical Investigation
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Clair Francomano
What is the purpose of this study?The Ehlers-Danlos Syndromes (EDS) are a group of heritable disorders of connective tissue with joint hypermobility, chronic pain and a wide range of other conditions that overlap in symptoms including the musculoskeletal system, respiratory system, dental and neurologic issues. We think there may be …
Use of eye tracking to aid in autism risk detection
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Rebecca McNally Keehn
What is the purpose of this study?The study will use a non-invasive remote eye-tracking system (Eyelink Portable Duo) to acquire a short series (less than 15 mins) of eye-tracking measures (e.g., look time, pupil diameter), which may be associated with autism in young children ages 12-48 months. We will recruit …
ISCHEMIC HEART DISEASE REGISTRY
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Rohan Dharmakumar
What is the purpose of this study?The purpose of the Ischemic Heart Disease Registry is to collect and store medical information from individuals with the same disease. The aim of this registry is to gather a large pool of information sufficient to determine how outpatient investigations of suspected ischemic heart …
The Assessment of Smart Phone Everyday Tasks (ASSET): A new IADL test for early AD
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Liana Apostolova, MD
What is the purpose of this study?The overall goal of this project is to validate a novel performance-based IADL instrument that uses a smartphone to assess healthcare-related daily activities, ASSET. This IADL test has been designed to tap the high-level tasks that challenge seniors in daily life, to serve as …
Efficacy & Safety of Olvi-Vec and Platinum-doublet + Bevacizumab Compared to Physician's Choice of Chemotherapy and Bevacizumab in Platinum-Resistant/Refractory Ovarian Cancer (PRROC) (OnPrime, GOG-3076)
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Jessica Parker Metter
What is the purpose of this study?The OnPrime study is a multi-center, randomized open-label phase 3 study evaluating the safety and efficacy of Olvi-Vec followed by platinum-doublet chemotherapy and bevacizumab compared to the Active Comparator Arm with Physician's Choice of chemotherapy and bevacizumab in women diagnosed with platinum-resistant/refractory ovarian cancer …
A Study of the Drug Selinexor With Radiation Therapy in Patients With Newly-Diagnosed Diffuse Intrinsic Pontine (DIPG) Glioma and High-Grade Glioma (HGG)
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Sandeep Batra, MD
This phase I/II trial tests the safety, side effects, and best dose of selinexor given in combination with standard radiation therapy in treating children and young adults with newly diagnosed diffuse intrinsic pontine glioma (DIPG) or high-grade glioma (HGG) with a genetic change called H3 K27M mutation. It also tests …
A Prospective, Single-Arm Multi-Center Study of the HARMONIC 700, 5 mm Diameter Shears with Advanced Hemostasis in Pediatric Surgical Procedures (General) and Adult Surgical Procedures (General, Gynecological, Urological, and Thoracic)
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Troy Markel, MD
What is the purpose of this study?The main purpose of this study is to demonstrate acceptable performance and assess safety of the HARMONIC 700 Shears device in a post-market setting when used per the instructions for use in pediatric and adult surgical procedures.THIS STUDY IS ENROLLING BY INVITATION ONLY - …
A multi-center, open-label study to determine the dose and safety of oral asciminib in pediatric patients with Philadelphia chromosome positive chronic myeloid leukemia in chronic phase (Ph+ CML-CP), previously treated with one or more tyrosine kinase inhibitors
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Rachael Schulte
What is the purpose of this study?The aim of this study is to support development of asciminib in the pediatric population (1 to <18 years) with Philadelphia chromosome positive chronic myeloid leukemia in chronic phase (PH+ CML-CP) previously treated with one or more Tyrosine kinase inhibitor (TKIs). THIS STUDY IS ENROLLING …
A Randomized Phase II Study of Letrozole Versus Observation in Patients with Newly Diagnosed Uterine Leiomyosarcoma
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Lisa Landrum, MD, PhD, MS
What is the purpose of this study?This is a clinical trial to test letrozole in patients with uterine leiomyosarcoma. The main question is will treatment with letrozole extend progression-free survival in patients. Patients will receive 2/5 mg of letrozole daily. Translational Objectives: 1. To preliminarily assess IHC hormone receptor expression and correlation …
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