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Found 716 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

A Groupwide Pilot Study to Test the Tolerability and Biologic Activity of the Addition of Azacitidine (NSC# 102816) to Chemotherapy in Infants With Acute Lymphoblastic Leukemia (ALL) and KMT2A(MLL) Gene Rearrangement

S
Sandeep Batra, MD
1 years and younger
All genders
This pilot phase II trial studies the side effects of azacitidine and combination chemotherapy in infants with acute lymphoblastic leukemia and KMT2A gene rearrangement.
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A Phase 1a/1b Study of an Anti-IDO-1 Agent (LY3381916) Administered Alone or in Combination with Anti-PD-L1 Checkpoint Antibody (LY3300054) in Solid Tumors

S
Shadia Jalal, MD
18-100 years
All genders
The purpose of this study is to evaluate the safety of the study drug LY3381916 administered alone or in combination with anti-programmed cell death ligand 1 (PD-L1) checkpoint antibody (LY3300054).
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A Phase 2 Study of the MEK Inhibitor Trametinib in Children With Relapsed or Refractory Juvenile Myelomonocytic Leukemia

S
Sandeep Batra, MD
21 years and younger
All genders
This phase II trial studies how well trametinib works in treating patients with juvenile myelomonocytic leukemia that has come back or does not respond to treatment.
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A Phase 3 Trial of Antibody hu3F8 and Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) in High-Risk Neuroblastoma Patients with Primary or Secondary Refractory Osteomedullary Disease

T
Terry Vik, MD
1-100 years
All genders
The purpose of this research trial is to find out about the treatment effects of an antibody called humanized 3F8 (hu3F8).
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A First-in-Human Phase I Trial to Determine the Safety and the Pharmacokinetic Profile of DSP-0509 a Synthetic Toll-Like Receptor 7 (TLR-7) Agonist in Adult Patients With Advanced Solid Tumors

S
Shadia Jalal, MD
18-100 years
All genders
This is a Phase 1, open label, multi-center study of intravenously administered DSP-0509 in adult subjects with advance solid tumors that are refractory to standard treatment.
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Neural and Cognitive Bases of Language Processing

J
Jiyeon Lee
30-85 years
All genders
Purdue Aphasia Research Lab invites individuals with stroke-induced aphasia to participate in a NIH-funded research project. The goal of the project is to examine how different types of cues facilitate sentence production and comprehension in persons with aphasia. The findings will lead to development of more cost-effective interventions for persons …
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A Phase 1/2 Trial of VX15/2503 in Children Adolescents or Young Adults With Recurrent or Relapsed Solid Tumors

J
James Croop, MD, PhD
1-30 years
All genders
This phase I/II trial studies the side effects and best dose of anti-SEMA4D monoclonal antibody VX15/2503 (VX15/2503) and to see how well it works in treating younger patients with solid tumors that have come back after treatment, or do not respond to treatment.
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STEPS to Enhance Physical Activity (STEPS) after Hematopoietic Stem Cell Transplantation (HCT) for Multiple Myeloma

E
Eileen Hacker
18-100 years
All genders
The purpose of this pilot study is to test the preliminary effects of a free-living physical activity intervention, STEPS to Enhance Physical Activity (STEPS), compared to usual care on fatigue (tiredness), functional ability (ability to perform tasks associated with daily living, like moving from a sitting to standing position), muscle …
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Phase II Trial of Panitumumab Nivolumab and Ipilimumab for KRAS/NRAS/BRAF Wild-type MSS Refractory Metastatic Colorectal Adenocarcinoma

P
Patrick Loehrer, MD
18-100 years
All genders
The purpose of this research study is to learn more about the safety and anti-cancer activity of a 3-drug combination therapy involving antibodies nivolumab, ipilimumab and panitumumab.
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Phase II Trial of Atezolizumab in BCG-Unresponsive Non-muscle Invasive Bladder Cancer

N
Nabil Adra, MD
18-100 years
All genders
This phase II trial studies how well atezolizumab works in treating patients with non-muscle invasive bladder cancer that has come back and has not responded to treatment with Bacillus Calmette-Guerin (BCG).
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