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Found 771 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Study of Investigational Treatment for Slow-Growing Brain Tumors in Children and Young Adults

S
Sandeep Batra, MD
2 years - 21 years
All genders
Phase 3
Interventional
This study investigates treatment options for children and young adults with low-grade glioma (LGG), a type of brain tumor. The purpose of this study is to compare the effects of an investigational medication with standard chemotherapy treatments, carboplatin and vincristine, in patients who do not have a specific genetic mutation …
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Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy

S
Sandeep Batra, MD
1 year - 25 years
All genders
Phase 3
Interventional
What is the purpose of this study?This phase III trial studies whether inotuzumab ozogamicin added to post-induction chemotherapy for patients with High-Risk B-cell Acute Lymphoblastic Leukemia (B-ALL) improves outcomes. This trial also studies the outcomes of patients with mixed phenotype acute leukemia (MPAL), and B-lymphoblastic lymphoma (B-LLy) when treated with …
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Filgotinib in Long-Term Extension Study of Adults With Crohn's Disease (DIVERSITYLTE)

M
Matthew Bohm, DO
18 years or above
All genders
Phase 3
Interventional
The primary objective of this study is to observe the long-term safety of filgotinib indults who have completed or met protocol specified efficacy discontinuation criteria in agotinib treatment study in Crohn's disease (CD).
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Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG (PACES)

J
Joel Corvera, MD
18 years or above
All genders
Phase 3
Interventional
The primary objective of this study is to evaluate the effectiveness (prevention ofhromboembolic events) and safety (major bleeding) of adding oral anticoagulation (OAC) to background antiplatelet therapy in patients who develop new-onset post-operative atrialbrillation (POAF) after isolated coronary artery bypass graft (CABG) surgery. All patients with a qualifying POAF event, …
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The natural history of C. trachomatis urethral infections in men who have sex with women

The natural history of C. trachomatis urethral infections in men who have sex with women

S
Stephen Jordan
18 years - 100 years
Accepts healthy volunteer
Male
What is the purpose of this study?Chlamydia is the most common bacterial sexually transmitted infection (STI) in the United States and is caused by the bacteria Chlamydia trachomatis, or “CT” for short. CT infects both men and women. The purpose of this study is to understand what causes some men …
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Longitudinal Study of Genetic Causes of Intrahepatic Cholestasis (LOGIC) (LOGIC)

J
Jean Molleston, MD
25 years or below
All genders
Observational
Cholestasis is a condition in which bile is not properly transported from the liver to the. Cholestasis can be caused by an array of childhood diseases, including the genetic diseases Alagille syndrome (ALGS), alpha-1 antitrypsin (a-1AT) deficiency, bile acidynthesis and metabolism defects, and progressive familial intrahepatic cholestasis (PFIC) or benign …
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Healthy Females Needed To Help Develop A Vaccine for Chlamydia (IMPACT Study)

Healthy Females Needed To Help Develop A Vaccine for Chlamydia (IMPACT Study)

S
Stephen Jordan
18 years - 40 years
Accepts healthy volunteer
Female
Chlamydia trachomatis (CT) is the most reported bacterial sexually transmitted infection (STI) in the United States. Untreated chlamydia infection in women can result in pelvic inflammatory disease, infertility, and/or ectopic pregnancy. Although chlamydia rates are at an all-time high, no vaccine is available because we don't yet understand how immunity …
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Vitamin C Supplementation to Pregnant Smokers: Follow-up of 2 Randomized Trials Plus Changes in DNA Methylation (VCSIP-ECHO)

R
Robert Tepper, MD
6 months - 11 years
All genders
Observational
In a randomized clinical trial (RCT) published in JAMA, the investigators have providedvidence that vitamin C supplementation (500 mg daily during pregnancy) ameliorates theking during pregnancy on offspring lung function and subsequentdence of wheeze by 48% through 1 year of age. The investigators are currently completingd RCT of vitamin C …
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Genomics of Obesity and Asthma – The Role of Adipose Tissue (GenOAAT)

E
Erick Forno
6 years - 24 years
Accepts healthy volunteer
All genders
Researchers at Indiana University School of Medicine are conducting a research study to better understand how obesity makes asthma and lung function worse. Obesity and asthma are two of the most important health problems affecting adolescents and adults. In the last few years, we haveund evidence that the amount of …
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A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)

S
Sherif Farag, MD
All genders
Observational
This study is an access and distribution protocol for unlicensed cryopreserved cord blood units (CBUs) in pediatric and adult patients with hematologic malignancies and otherdications.
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