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Found 743 results
A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Spirituality in Adolescents and Young Adults with Cancer: A Qualitative Descriptive Study
S
Sheri Robb
What is the purpose of this study?The purpose of this proposed qualitative dissertation study is to describe AYA's personal experiences of spirituality during cancer diagnoses and treatment. Findings will advance our conceptual understanding of AYA spirituality and inform the subsequent development of reliable measures and meaningful interventions. THIS STUDY IS …
A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab
J
Jenny Belsky, DO
This phase III trial compares the effect of adding immunotherapy (brentuximab vedotin and nivolumab) to standard treatment (chemotherapy with or without radiation) to the standard treatment alone in improving survival in patients with stage I and II classical Hodgkin lymphoma. THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with most …
Evaluating Disparities in Precision Oncology: An Observational Trial in the context of a Real-World Academic Practice Model (EDPO)
B
Bryan Schneider, MD
What is the purpose of this study?This is a non-randomized observational trial designed to collect detailed clinical, social determinant, and genomic data from patients enrolled in molecular oncology tumor boards across four comprehensive cancer centers.THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with most oncology trials, patients are not …
A Study With Tovorafenib (DAY101) as a Treatment Option for Progressive, Relapsed, or Refractory Langerhans Cell Histiocytosis
A
Anthony Ross
This phase II trial tests the safety, side effects, best dose and activity of tovorafenib (DAY101) in treating patients with Langerhans cell histiocytosis that is growing, spreading, or getting worse (progressive), has come back (relapsed) after previous treatment, or does not respond to therapy (refractory). Langerhans cell histiocytosis is a …
Nivolumab and Tovorafenib for Treatment of Craniopharyngioma in Children and Young Adults (PNOC029)
S
Scott Coven
The current study assesses the tolerability and efficacy of combination therapy with PD-1 (nivolumab) and pan-RAF-kinase (Tovorafenib) inhibition for the treatment of children and young adults with craniopharyngioma.THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with most oncology trials, patients are not actively “recruited,” but are screened by their …
Phosphate Binder Therapy and Chronic Kidney Disease in Children
M
Myda Khalid
What is the purpose of this study?The purpose of this placebo-controlled study is to determine how well ferric citrate will lower the level of FGF23, maintain or correct anemia and iron levels in the blood and maintain normal levels of serum phosphate in children with CKD stages 3 and 4 …
Breath-based Diagnosis of Pulmonary Exacerbations in Children with Cystic Fibrosis
M
Mangilal Agarwal
What is the purpose of this study?The purpose of this study is to obtain and measure compounds found in exhaled breath samples collected from children with Cystic Fibrosis (CF). These compounds should be different when CF patients are healthy compared to when they have an exacerbation. This information could help …
A Multicenter Randomized Controlled Trial of Surveillance vs. Endoscopic Therapy for Barrett's Esophagus With Low-grade Dysplasia (The SURVENT Trial)
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Mohammad Al-Haddad, MD
What is the purpose of this study?The purpose of this study is to learn the best approach to treating patients with known or suspected Barrett's esophagus by comparing endoscopic surveillance to endoscopic eradication therapy. This is a multicenter study involving several academic, community and private hospitals around the United States. …
A Phase 3, Randomized, Double-Blind, Placebo-Controlled Program toEvaluate the Efficacy and Safety of Tulisokibart in Participants with Moderately to SeverelyActive Crohn's Disease
M
Monika Fischer, MD
What is the purpose of this study?The purpose of this protocol is to evaluate the efficacy and safety of tulisokibart in participants with moderately to severely active Crohn's disease. The protocol consists of 2 studies. Study 1 includes induction and maintenance treatment, and Study 2 includes only induction treatment. Each study …
Prevention/Reduction of ASRs and PTSD to Sustain Civilian Performance with Sublingual Cyclobenzaprine HCl (TNX-102 SL) - (Optimizing Acute Stress reaction Interventions with TNX-102 SL - OASIS)
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Paul Musey, MD
This study will examine the safety and efficacy of TNX-102 SL to reduce ASR symptoms and behavioral changes among patients presenting to the emergency department (ED) after motor vehicle collision (MVC). Specifically, the investigators will perform the Optimizing Acute Stress reaction Interventions with TNX-102 SL (OASIS) Trial, a double-blind placebo-controlled …
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