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Found 743 results
A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
A Phase III, Randomised, Double-blind Study to Evaluate the Effect of Balcinrenone/Dapagliflozin, Compared with Dapagliflozin, on the Risk of Heart Failure Events and Cardiovascular Death in Patients with Heart Failure and Impaired Kidney Function
W
Wayne Gray
The purpose of this study is to investigate the effect of balcinrenone/dapagliflozin compared with dapagliflozin, on the risk of CV death, HF event with and without hospitalization, in patients with chronic HF, impaired kidney function, and who have had a recent HF event.THIS STUDY IS ENROLLING BY INVITATION ONLY
Azithromycin Treatment for Respiratory Syncytial Virus-induced Respiratory Failure in Children
M
Michael Hobson, MD
What is the purpose of this study?The overarching hypothesis of the ARRC trial is that administration of Azithromycin (AZM) during acute, Respiratory Syncytial Virus (RSV)-induced respiratory failure will be beneficial, mediated through the matrix metalloproteinase (MMP)-9 pathway. THIS STUDY IS ENROLLING BY INVITATION ONLY
A Phase 2A, 2-Part, Open-Label, Non-Randomized, Multicenter, Single and Multiple DoseTrial to Evaluate Pharmacokinetics, Safety and Tolerability of Aztreonam and Avibactam ±Metronidazole in Neonates and Infants From Birth to Less Than 9 Months of Age WithSuspected or Confirmed Infections Due to Gram-Negative Pathogens Requiring IntravenousAntibiotic Treatment
A
Anna Elizabeth Thomas
The purpose of this study is to learn about the safety and effects of ATM-AVI for the possible treatment of infections caused by a type of bacteria called gram-negative bacteria.The study medicine is a combination of an antibiotic, aztreonam (ATM), and another medicine, avibactam (AVI), which is used to help …
Patterns of cerebral oxygenation after ventricular reservoir placement and CSF removal: a pilot study
B
Beatrice Stefanescu
What is the purpose of this study?About 25% of babies born prematurely (before 32 weeks gestation) develop brain bleeds (intraventricular hemorrhage or IVH), which could progress to the serious complication of post-hemorrhagic hydrocephalus (PHH). Infants with PHH may require neurosurgical intervention to relieve the increased pressure that builds up within …
A Global Multi-Center Prospective Observational Cohort to Support Drug Development in Adult Patients with Primary Sclerosing Cholangitis
C
Craig Lammert, MD
What is the purpose of this study?To develop an appropriate real-world data comparator cohort to support the design, execution, and serve as an external control for interventional clinical trials in PSC. This is a Global, multi-center longitudinal observational cohort study. Collection of prospective clinical data to include liver-related clinical outcomes …
Fecal Microbiota Transplant (FMT) National Registry
M
Monika Fischer, MD
What is the purpose of this study?This is a national data registry of patients receiving fecal microbiota transplantation (FMT) or other gut-related-microbiota products designed to prospectively assess short and long-term safety and effectiveness. This registry will prospectively enroll 4,000 patients who undergo FMT at 75 sites throughout North America. This …
Safety and Efficacy of Endovascular Treatment ofIntracranial Aneurysms with Surpass Elite with GUARDian Flow Diverter(GUARD)
B
Bradley N. Bohnstedt, MD
The objective of the Safety and Efficacy of Endovascular Treatment of Intracranial Aneurysms with Surpass Elite with GUARDian Flow Diverter (GUARD) trial is to evaluate the safety and efficacy of the Surpass EliteTM with Guardian Flow Diverter System (FDS) in the treatment of unruptured, wide-neck saccular or fusiform, intracranial aneurysms …
Osteosarcoma Predisposition - Developing New Models to Study Pediatric Osteosarcoma Development
J
Jennifer Ivanovich
What is the purpose of this study?In partnership with Indiana Biosciences Research Institute, we will develop new models to study pediatric osteosarcoma. We will invite children with Li-Fraumeni syndrome, hereditary retinoblastoma syndrome, or Rothmund-Thompson syndrome to participate. These three syndromes are associated with an increased risk to develop osteosarcoma. THIS STUDY …
Pediatric Behavioral Health Integrated Care: Indiana Statewide Strategic Plan to Address the Growing Mental Health Crisis
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Matthew Aalsma
What is the purpose of this study?The purpose of this study is to learn more about the impact of a substance use disorder (SUD) Integrated Behavioral Health Program (IBH) on primary care providers (PCPs) willingness to engage in and views/attitudes around adolescent SUD treatment as well as IBH team dynamics. THIS …
Offspring Neurodevelopment and Growth after Early Antihypertensive Therapy or Preeclampsia in Women with Chronic Hypertension and Pregnancy (CHAP Child)
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David Haas, MD
What is the purpose of this study?This study is being conducted to evaluate the current state of knowledge regarding long-term child outcomes among children born to women with mild CHTN who received antihypertensive therapy in pregnancy or who had preeclampsia. This study will compare long-term outcomes, including neurodevelopment and growth. …
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