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Found 743 results

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Measuring Allostatic Load in a Pregnant Cohort

J
Jasmine D Johsnon
18 years - 100 years
All genders
Observational
What is the purpose of this study?Our central hypothesis is that structural and personally-mediated racism and its association with adverse pregnancy outcomes can be measured. The overall objectives of this study are to measure the burden of racism in an obstetric population and its impact on preterm birth and hypertensive …

Indiana Neurosciences Biorepository at Riley Hospital for Children

J
Jignesh Tailor
100 years or below
Accepts healthy volunteer
All genders
The purpose of this study is to collect tissue, blood, and CSF in patients with all conditions affecting the brain and spinal cord, with the goal of developing a repository of biospecimen and clinical data for neurosurgical patients within IU Health. This may help us learn how certain conditions develop …

Master Screening and Reassessment Protocol (MSRP) for TierAdvancement in the NCI myeloMATCH Clinical Trials

R
Rita Assi
18 years - 100 years
All genders
What is the purpose of this study?This MyeloMATCH Master Screening and Reassessment Protocol (MSRP) evaluates the use of a screening tool and specific laboratory tests to help improve participants' ability to register to clinical trials throughout the course of their myeloid cancer (acute myeloid leukemia or myelodysplastic syndrome) treatment. This …

Indiana University Gastric Electrical Stimulation Registry

J
John Wo, MD
18 years - 80 years
All genders
Observational
What is the purpose of this study?The purpose of this study is to develop a clinical registry in patients with Gastric Electrical Stimulation (GES) therapy for gastroparesis to support future gastrointestinal therapies, medical procedures and diagnostics. This clinical registry will support future clinical and translational research. Gastroparesis is an illness …

A Multicenter, Open-label, Phase 1/2, Dose-escalation and Subsequent Safety Extension Study of Subcutaneous KK8123 in Adult Patients with X-linked Hypophosphatemia

E
Erik Imel, MD
18 years - 65 years
All genders
Phase 1/2
Interventional
The purpose of this study is to test the safety and effectiveness of an investigational drug called KK8123 in adults with X-linked hypophosphatemia. THIS STUDY IS ENROLLING BY INVITATION ONLY - Potential subjects may come from our practice. If they are from our practice, the chart may be reviewed for additional …

A Phase 1 study of GRN163L (Imetelstat, IND# 170891, NSC# 754228) in combination with fludarabine and cytarabine for patients with acute myeloid leukemia that is in second or greater relapse or that is refractory to relapse therapy; myelodysplastic syndrome or juvenile myelomonocytic leukemia in first or greater relapse or is refractory to relapse therapy

B
Brian Weiss
1 year - 18 years
All genders
Phase 1
This phase I trial tests the safety, side effects, and best dose of imetelstat in combination with fludarabine and cytarabine in treating patients with acute myeloid leukemia (AML), myelodysplastic syndrome (MDS) or juvenile myelomonocytic leukemia (JMML) that has not responded to previous treatment (refractory) or that has come back after …

Role of neutrophil-specific NOX2 in alcohol-induced liver injury

S
Suthat Liangpunsakul, MD
18 years - 70 years
Accepts healthy volunteer
All genders
What is the purpose of this study?NADPH oxidase 2 (NOX2) is the isoform of NOX found in phagocytes including neutrophils, NOX2 activation generates reactive oxygen species (ROS) with antimicrobial activities. Patients with advanced alcoholic cirrhosis or alcoholic hepatitis are more susceptible to infections due to deficient ROS production by neutrophils. …

Hearing Health in Residents of Senior Living Facilities

I
Irina Castellanos
60 years or above
Accepts healthy volunteer
All genders
The purpose of this study is to determine the prevalence rate of hearing loss and cerumen impaction in residents of senior living facilities and identify barriers to managing hearing devices and cerumen. Our long-term objective is to improve the effective identification and management of hearing health in senior living facilities. THIS …

Assessment of peri-implantitis microflora and its interaction with host tissue.

M
Monica Gibson
18 years - 75 years
Accepts healthy volunteer
All genders
What is the purpose of this study?The study will investigate molecular markers associated with dental implant diseases like peri-implantitis to elucidate the mechanistic pathway involved. •    The primary goal of this study is to use GCF or PICF to analyze the microflora present around implants in disease condition and compare it …

ASSESS ALL ALS study

C
Cynthia Bodkin, MD
18 years - 100 years
Accepts healthy volunteer
All genders
What is the purpose of this study?The primary goal for this protocol is to establish a robust clinical trial-like infrastructure to coordinate recruitment, enrollment, and longitudinal follow up of a cohort of people with ALS and associate control participants. The overarching goal of the consortium is to prospectively collect, store …
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