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Found 743 results
A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Indiana Neuroimaging and Biomarker Study of Anti-Amyloid Treatments
D
Donna Wilcock
What is the purpose of this study?The goal of this research is to create a repository of brain imaging and biological samples to study individuals undergoing clinical treatment with anti-amyloid therapies and compare them with samples and images from healthy individuals and cognitively impaired individuals not receiving these treatments. We …
Parent Social Buffering and Dyadic Music Intervention to Decrease Distress in Infants and Young Children during Hematopoietic Stem Cell Transplant and their Parents
S
Sheri Robb
The goal of the proposed study is to adapt an existing music-based intervention (Active Music Engagement; AME) using the ORBIT model, for infants and young children (3 years of age and under) undergoing stem cell transplant and their parents. Previous studies suggest that AME produces positive psychosocial outcomes for children …
A Phase II Trial Evaluating Chemotherapy Followed by Response-Based Reduced Radiation Therapy for Patients With Central Nervous System Germinomas
S
Sandeep Batra, MD
What is the purpose of this study?This phase II trial studies how well lower dose radiotherapy after chemotherapy works in treating children with central nervous system (CNS) germinomas. Radiation therapy uses high energy x-rays, particles, or radioactive seeds to kill cancer cells and shrink tumors. Carboplatin is in a class …
Investigating the role of T2R38 taste receptors in influencing the susceptibility to Periodontitis
M
Mythily Srinivasan
What is the purpose of this study?The aim of this study is to investigate and correlate the susceptibility of homozygous recessive genotype (AVI/AVI, non-taster) individuals to periodontitis. Using saliva collected from the subjects for research purposes and compared with periodontal examination results (standard of care), we hypothesize that individuals with …
A Randomized Phase II Study Comparing Cytarabine + Daunorubicin(7+3) vs (Daunorubicin and Cytarabine) Liposome, Cytarabine + Daunorubicin +Venetoclax, Azacitidine + Venetoclax, and (Daunorubicin and Cytarabine) Liposome+ Venetoclax in Patients Aged 59 or Younger Who are Considered High-Risk(Adverse) Acute Myeloid Leukemia as Determined by MYELOMATCH; AMyeloMATCH Clinical Trial
R
Rita Assi
What is the purpose of this study?This phase II MyeloMATCH treatment trial tests whether the standard approach of cytarabine and daunorubicin in comparison to the following experimental regimens works to shrink cancer in patients with high risk acute myeloid leukemia (AML): 1) daunorubicin and cytarabine liposome alone; 2) cytarabine and …
Utilization of FibroScan in Fontan Associated Liver Disease prior to and after heart transplant or placement of single ventricle ventricular assist device
What is the purpose of this study?In this study, we propose to assess: 1) the role of FibroScan in patients with FALD prior to and after heart transplant or placement of single ventricle ventricular assist device (SVAD); 2) the association between liver stiffness measurement (LSM) from FibroScan and cardiac events, …
A Randomized Trial of the Insulin-only Bionic Pancreas in Cystic Fibrosis Related Diabetes
V
Viral Shah
This multi-center randomized controlled trial (RCT) will compare efficacy and safety endpoints using the insulin-only configuration of the iLet Bionic Pancreas System (BP) versus a control group using their usual care insulin delivery method and continuous glucose monitoring (CGM) during a 13-week study period in individuals ≥14 years old with …
Collaborative Study on the Genetics of Alcoholism
M
Martin Plawecki, MD, PhD
What is the purpose of this study?The overarching aim of the COGA project is to identify and understand genetic mechanisms underlying alcohol use disorders and related disorders. The current research data collection methods represent a continuation of the COGA methodologies that have evolved over the course of the study. The …
A post-market, prospective, multi-center, single-arm study evaluating the safety and efficacy of the 3M V.A.C. Peel and Place Dressing used in conjunction with 3M V.A.C.® Therapy
G
Greg Westin
The purpose of this clinical study is to obtain post-market safety and efficacy data when the V.A.C.® Peel and Place dressing is used in conjunction with 3M™ V.A.C.® Therapy.THIS STUDY IS ENROLLING BY INVITATION ONLY
Sinonasal Therapies and Histologic Correlations for Patients with Cystic Fibrosis in the Era of Highly Effective Modulator therapy
E
Elisa Illing
Establish a protocol for de-escalation of sinonasal therapies for patients on cystic fibrosis transmembrane regulator (CFTR) modulator therapies in a multidisciplinary fashion that includes a Rhinology perspective. Test the hypothesis that patients with cystic fibrosis on CFTR modulator therapy with refractory sinus disease exhibit continued tissue neutrophilic inflammation. THIS STUDY IS …
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