A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
What is the purpose of this study?This phase I/II trial evaluates the highest safe dose, side effects, and possible benefits ofgavivint in treating patients with solid tumors that has come back (recurrent) or does notd to treatment (refractory). Tegavivint interferes with the binding of beta-catenin to TBL1, which may help …
What is the purpose of this study?Related donor Adenovirus (ADV) specific cytotoxic T cells (CTLs) manufactured with theyi CliniMACS Prodigy Cytokine Capture System will be administered intravenously in inhildren, adolescents and young adults with refractory ADV infection post Allogeneic Hematopoietic Stem Cell Transplantation (AlloHSCT), with primary immunodeficiencies (PID) ord organ …
What is the purpose of this study?CMV cytotoxic T cells (CTLs) manufactured with the Miltenyi CliniMACS Prodigy Cytokine Capture System will be administered in children, adolescents and young adults (CAYA) with refractory cytomegalovirus (CMV) infection post Allogeneic Hematopoietic Stem Cell Transplantation (AlloHSCT), with primary immunodeficiencies (PID) or post solid organ …
What is the purpose of this study?This phase III trial compares the effects of nivolumab with chemo-immunotherapy versushemo-immunotherapy alone in treating patients with newly diagnosed primary mediastinal B-cell lymphoma (PMBCL). Immunotherapy with monoclonal antibodies, such as nivolumab, may help the body's immune system attack the cancer, and may interfere with …
What is the purpose of this study?This phase II trial studies the effects of trastuzumab deruxtecan in treating patients with HER2 positive osteosarcoma that is newly diagnosed or has come back (recurrent). Trastuzumab deruxtecan is a monoclonal antibody, called trastuzumab, linked to a chemotherapy drug called deruxtecan. Trastuzumab attaches to …
What is the purpose of this study?This is an open label randomized phase II trial of maintenance oral etoposide vs. observationwith relapsed GCT treated with high-dose chemotherapy (HDCT) and peripheral-blood(PBSCT).THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with most oncology trials, patients are not actively “recruited,” but are screened …
What is the purpose of this study?This phase II trial studies how well combination chemotherapy works in treating patients withwly diagnosed stage II-IV diffuse anaplastic Wilms tumors (DAWT) or favorable histology Wilms tumors (FHWT) that have come back (relapsed). Drugs used in chemotherapy regimens suchH-3 (vincristine, doxorubicin, cyclophosphamide, carboplatin, etoposide, …
Are you interested in being opioid-free? Join our study!Researchers at Indiana University School of Medicine are looking for volunteers to take part in a study to test an investigational drug called Tezampanel for opioid withdrawal. The term “investigational drug” means it is not approved by the Food and Drug Administration …
What is this study about?The objective of this study is to assess the pharmacokinetics (PK), efficacy, and safety of risankizumab in pediatric subjects with moderately to severely active CD aged 2 to < 18 years old who have had intolerance or inadequate response to aminosalicylates, oral locally acting corticosteroids, systemic …
What is this study about?The PERFORMANCE III study is a prospective, multicenter single-arm, open label study to evaluate the safety and effectiveness of the Neuroguard IEP® Direct System for the treatment of carotid artery stenosis in subjects at elevated risk for carotid endarterectomy (CEA).Eligible patients greater than or equal to …
