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Found 743 results
A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
The Carevix Device: Assessing pain and effectiveness of a suction-based cervical stabilizer for IUD insertions in the clinic setting: a randomized, controlled (CARE) trial
A
Alissa Conklin
To assess patient experienced pain and provider experienced bleeding and effectiveness of a suction-based cervical stabilizer through a randomized trialTHIS STUDY IS ENROLLING BY INVITATION ONLY - All patients who are above age 18 and able to consent for themselves who are receiving an IUD insertion in the IU Health-based …
A phase 1, open-label, single arm study to evaluate pharmacokinetics, safety, and tolerability of Saroglitazar Magnesium dosed on alternate days in subjects having moderate hepatic impairment with cirrhosis due to cholestatic liver disease
R
Raj Vuppalanchi, MD
To evaluate PK after Saroglitazar Magnesium 1 mg dose on alternate days in subjects with moderate hepatic impairment with cirrhosis due to CLD based on Child-Pugh-Turcotte (CPT) score.To assess safety and tolerability of Sa-roglitazar Magnesium 1 mg dose on alter-nate days in subjects with moderate hepatic impairment with cirrhosis due …
Project ADAM: Long-Term Outcomes
A
Adam Kean, MD
The purpose is to establish a database of SCA (Sudden Cardiac Arrest) victims to better characterize the predisposing factors, causes, emergency response, diagnoses, procedures, and long-term outcomes surrounding this life-threatening emergency. Expanding to a national scope rather than isolated communities or regional areas, will change the way we view SCA …
CHronic nonbacterial Osteomyelitis International Registry (CHOIR)
M
Melissa Oliver, MD
What is the purpose of this study?The objective of the study is to establish a prospective disease registry for chronic recurrent multifocal osteomyelitis (CRMO)/chronic nonbacterial osteomyelitis (CNO) in order to investigate the natural history of the disease and the responses of patients to different clinical managements over 5 yearsTHIS STUDY …
Geometric Engineering of Liver Organoid Culture in Pediatric Liver Diseases
C
Chao Jarasvaraparn
What is the purpose of this study?Chronic liver disease (CLD) in children can be caused by a variety of conditions and have serious consequences if left untreated. Liver organoids are defined as 3D structure derived from human liver tissue and is a promising new approach to treating liver disease in …
A Phase III Trial of One vs. Two Years of Maintenance Olaparib, with or without Bevacizumab, in Patients with BRCA1/2 Mutated or Homologous Recombination Deficient (HRD+) Ovarian Cancer Following Response to First Line Platinum-Based Chemotherapy
J
Jessica Parker Metter
What is the purpose of this study?This phase III trial compares the effect of olaparib for one year versus two years, with or without bevacizumab, for the treatment of BRCA 1/2 mutated or homologous recombination deficient stage III or IV ovarian cancer. Olaparib is a polyadenosine 5'-diphosphoribose polymerase (PARP) enzyme …
A Phase 3, Multicenter, Open-label, Basket, LTE Study to Evaluate the Safety of Guselkumab in Pediatric Participants With Crohn's Disease, Ulcerative Colitis, or Juvenile Psoriatic Arthritis
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Marian Pfefferkorn
The purpose of this study is to evaluate long-term safety of subcutaneous guselkumab in pediatric participants with moderately to severely active ulcerative colitis, or moderately to severely active Crohn's disease, or juvenile psoriatic arthritis (jPsA).THIS STUDY IS ENROLLING BY INVITATION ONLY - This study is only enrolling individuals who have …
PSMA-PET to Guide Prostatectomy: A Sub-study
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Clinton Bahler, MD
This sub-study consists of a single treatment group of men that require a PET scan to guide their radical prostatectomy, every subject will receive an MRI and the PSMA (prostate specific membrane antigen) PET scan prior to their surgery to determine if the PSMA PET scan is helpful in detecting …
A multisite, observational study to examine the effects of childhood-onset SLE on cognitive functions over time, using the pedANAM tool for cognitive and behavioral assessments
S
Stacey Tarvin, MD
PRIMARY OBJECTIVES:The study's main objective is to track and analyze the long-term outcomes of neuropsychiatric systemic lupus erythematosus (NPSLE) in children and how it affects their cognitive functions over time. This includes monitoring changes in cognitive performance using the pedANAM tool, which gives a detailed understanding of the cognitive trajectories …
A type I hybrid effectiveness-implementation study of a parent-centered tool to promote shared decision-making in hypospadias care
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Martin Kaefer, MD
What is the purpose of this study?Aim 1. Compare the effect of the Hypospadias Hub Intervention vs. control on the quality of SDM. Aim 2. Compare the effect of the Hypospadias Hub Decision Support Intervention vs. control on decisional conflict, decision-relevant knowledge, and decisional regret. Aim 3. Assess barriers and …
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