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Found 768 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

A Prospective, Single-arm, Multi-center, Open-label Trial Evaluating the Continuous Application of Prevena Therapy for up to 14 days

L
Leonard Buller
22 years or above
All genders
Interventional
What is the purpose of this study?The purpose of this study is to demonstrate substantial equivalence in terms of safety to support an indication change related to the usage of Prevena Therapy for up to 14 days.  THIS STUDY IS ENROLLING BY INVITATION ONLY - The Principal Investigator will review the …
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A Pivotal, Prospective, Open-label, Multi-center Study of Safety and Effectiveness of Cochlear Implantation in an Expanded Population of Adults With Bilateral Sensorineural Hearing Loss

R
Rick Nelson, MD
18 years - 100 years
All genders
Interventional
What is the purpose of this study?This study aims to evaluate the safety and efficacy of cochlear implantation for adults with bilateral sensorineural hearing loss who currently do not meet the FDA-approved indications for cochlear implantation. Following cochlear implantation, participants will complete speech perception assessments and questionnaires over the course …
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Role of neutrophil-specific NOX2 in alcohol-induced liver injury

S
Suthat Liangpunsakul, MD
18 years - 70 years
Accepts healthy volunteer
All genders
What is the purpose of this study?NADPH oxidase 2 (NOX2) is the isoform of NOX found in phagocytes including neutrophils, NOX2 activation generates reactive oxygen species (ROS) with antimicrobial activities. Patients with advanced alcoholic cirrhosis or alcoholic hepatitis are more susceptible to infections due to deficient ROS production by neutrophils. …
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Assessment of peri-implantitis microflora and its interaction with host tissue.

M
Monica Gibson
18 years - 75 years
Accepts healthy volunteer
All genders
What is the purpose of this study?The study will investigate molecular markers associated with dental implant diseases like peri-implantitis to elucidate the mechanistic pathway involved. •    The primary goal of this study is to use GCF or PICF to analyze the microflora present around implants in disease condition and compare it …
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Cold Snare Endoscopic Mucosal Resection of Duodenal Adenomas more than or equal to 10 mm: A prospective cohort study

J
John Guardiola
18 years - 100 years
All genders
Observational
What is the purpose of this study?The purpose of this study is to evaluate the safety and effectiveness of Cold Snare Endoscopic Mucosal Resection (CS-EMR) for the removal of non-cancerous polyps that are located in the small bowel (duodenal) and are 10 millimeters or greater in size. The goal of this …
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ASSESS ALL ALS study

C
Cynthia Bodkin, MD
18 years - 100 years
Accepts healthy volunteer
All genders
What is the purpose of this study?The primary goal for this protocol is to establish a robust clinical trial-like infrastructure to coordinate recruitment, enrollment, and longitudinal follow up of a cohort of people with ALS and associate control participants. The overarching goal of the consortium is to prospectively collect, store …
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A Randomized Phase II Trial of Doxorubicin + Pembrolizumab Versus Doxorubicin Alone for the Treatment of Undifferentiated Pleomorphic Sarcoma (UPS) and Related Poorly Differentiated Sarcomas

S
Samantha Armstrong
18 years - 100 years
All genders
Phase 2
What is the purpose of this study?This phase II trial compares the effect of immunotherapy (pembrolizumab) plus chemotherapy (doxorubicin) to chemotherapy (doxorubicin) alone in treating patients with undifferentiated pleomorphic sarcoma (UPS) or a related poorly differentiated sarcoma that has spread from where it first started to other places in the …
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PREVENT ALL ALS

C
Cynthia Bodkin, MD
18 years - 100 years
All genders
Observational
What is the purpose of this study?PREVENT ALL ALS is a prospective, observational cohort study enrolling individuals at risk for carrying inherited genetic variants known to be causative for ALS. This is a longitudinal observational study involving collection of clinical data, outcomes andbiofluid samples. There is also an optional sub-study …
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Protrieve PROTECTOR Study

S
Sabah D. Butty, MD
18 years - 100 years
All genders
Interventional
What is the purpose of this study?The primary study objective is to evaluate the safety and effectiveness of the Protrieve Sheath in preventing clinically significant intraprocedural pulmonary embolism by providing embolic protection in the IVC during thrombectomy procedures to treat DVT. THIS STUDY IS ENROLLING BY INVITATION ONLY
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A Non-interventional, Prospective, Multi-country Study Collecting Real-world Data on the Characteristics, Treatment Patterns, and Outcomes of Patients With Transthyretin (ATTR) Amyloidosis

N
Noel Dasgupta
18 years or above
All genders
Observational
What is the purpose of this study?MaesTTRo is an international, longitudinal, non-interventional study of adult patients with transthyretin (ATTR) amyloidosis. The MaesTTRo study aims to enroll a global cohort of patients with transthyretin (ATTR) amyloidosis to longitudinally observe the natural course of the disease and describe real-world treatment patterns and …
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