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Found 743 results

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

CERAMENT G Device Registry

J
Jan Szatkowski
18 years - 100 years
All genders
Observational
What is the purpose of this study?This is an Observational Device Registry Study of CERAMENT G in normal use in accordance with the IFU. A Device Registry is a form of observational study that concerns the performance of a device in normal use. It is intended to collect data that …

Multi-Arm Multi-Stage Adaptive Platform Trial (APT) for the Acute Treatment of Traumatic Brain Injury

J
Jamie L. Bradbury, MD
18 years - 65 years
All genders
Interventional
The purpose of this study is to determine if experimental drug treatment improves recovery after TBI as compared to a control (placebo) group. Changes in recovery will be measured throughout the study. The study drugs lare approved by the U.S. Food and Drug Administration (FDA) but are being used "off-label" …

A Randomized Phase 3 Trial of Fludarabine/Cytarabine/Gemtuzumab Ozogamicin With or Without Venetoclax in Children With Relapsed AML

S
Sandeep Batra, MD
29 days - 21 years
All genders
Phase 3
A study to evaluate if the randomized addition of venetoclax to a chemotherapy backbone (fludarabine/cytarabine/gemtuzumab ozogamicin [GO]) improves survival of children/adolescents/young adults with acute myeloid leukemia (AML) in 1st relapse who are unable to receive additional anthracyclines, or in 2nd relapse.THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with …

A Randomized, Double-Blind, Placebo-Controlled, Phase 2b Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Patients With Graves' Disease

C
Cary Mariash, MD
18 years - 75 years
All genders
Phase 2/3
Interventional
This is a study to assess the efficacy, safety, and tolerability of IMVT-1402 in adult participants with Graves' disease (GD) who are hyperthyroid despite antithyroid drug (ATD) treatment.The primary objective of this study is to evaluate the efficacy of IMVT-1402 versus placebo as assessed by T3 (total triiodothyronine [T3] or …

Utility of Trypsinogen-2 in Early Detection and Follow Up of Post-pancreatectomy Acute Pancreatitis (PPAP)

N
Nicholas Zyromski, MD
18 years - 100 years
All genders
The goal of this study is to learn if urine trypsinogen can be used to diagnose post-pancreatectomy acute pancreatitis in patients undergoing pancreatectomy. Participants will have their urine measured by dipsticks during and after their surgery.Patients will be recruited from the patient group undergoing pancreatectomy at IU University hospital. These …

Post-Approval Study of the Renata Minima Stent in the Treatment of Vascular Stenoses in Neonates, Infants, and Small Children

R
Ryan Alexy, MD
100 years or below
All genders
Observational
This Post-Approval Study is a single arm, prospective, multi-center, open-label study of patients treated with the Renata Minima Stent System in the United States. The objective of the study is to continue the assessment of device performance and capture outcome data on use of the device in real-world use.THIS STUDY …

Comparing Optimal Step-down Therapy for Children with Invasive MRSA Trimethoprim-Sulfamethoxazole vs. Clindamycin for the Treatment of Children with Invasive MRSA Infections

J
James Wood, MD
60 days - 80 years
All genders
Interventional
What is the purpose of this study?This is a comparative effectiveness study of two antibiotics typically prescribed in the clinical setting of pediatric patients with osteoarticular infections (OAI, including acute osteomyelitis and septic arthritis) and head and neck infections (HNIs) caused by methicillin resistant Staphylococcus aureus (MRSA).. The goal of …

Discriminating Bone Quality in X-Linked Hypophosphatemia using Novel Imaging Biomarkers

C
Christopher Newman
18 years - 100 years
All genders
Observational
What is the purpose of this study?Patients with X-linked hypophosphatemia (XLH) have abnormal bone mineralization that results in soft bones. Bone density testing does not work well in these patients. So, the purpose of this study is to examine the role of MRI and other diagnostic testing in these patients.THIS …

Stone and Laser Therapies Post-Market Study SALT Study

M
Marcelino Rivera
18 years - 100 years
All genders
Observational
The purpose of this study is to obtain post-market safety and device performance data for qualified BSC Stone and BPH devices used during a diagnostic and/or therapeutic urinary tract procedure (e.g., transurethral or percutaneous access routes) or benign prostatic hyperplasia (BPH) treatment.THIS STUDY IS ENROLLING BY INVITATION ONLY - Potential …

Effect of Bariatric Outreach Clinic on Rural Bariatric Surgery Patients

R
Rosalie Carr
18 years - 100 years
All genders
What is the purpose of this study?We hypothesize that decreased travel time to receive perioperative bariatric surgery care will increase patient satisfaction and enrollment into the Indiana University Health bariatric surgery program. Improved patient satisfaction may also improve patient compliance and surgical outcomes.Goals: Assess patient satisfaction with the IUH West bariatric …
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