A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
This study investigates the use of an investigational medication, cabozantinib, in combination with standard chemotherapy for patients with newly diagnosed osteosarcoma. Osteosarcoma is a type of bone cancer that typically affects the long bones in the body. Cabozantinib is a kinase inhibitor, which means it works by blocking specific enzymes …
The purpose of this study is to look at pulmonary exacerbations in people with cysticbrosis (CF) that need to be treated with antibiotics given through a tube inserted into a vein (intravenous or IV). A pulmonary exacerbation is a worsening of respiratory symptoms inwith CF that needs medical intervention. Both …
The purpose of this study is to evaluate the pharmacokinetics, safety, tolerability andy of VX-121/tezacaftor/deutivacaftor (VX-121/TEZ/D-IVA) in CF participants with at1 triple combination responsive (TCR) mutation in the cystic fibrosis transmembraneductance regulator (CFTR) gene.
This protocol describes a multicenter, prospective randomized superiority trial of medialdyle fracture treatments comparing functional outcomes between children treated withve reduction and fixation or non-operative immobilization.
This protocol describes a multicenter, prospective randomized superiority trial comparingunctional outcomes between children treated with sedated reduction versus no formalduction.
The purpose of this collaborative CTSA (Clinical and Translational Science Award) applicationdevelop an innovative perioperative precision analgesia platform (PPAP) to improvegesia and reduce serious immediate and long-term adverse outcomes of perioperativeds in breastfeeding mothers and their infants
This study will evaluate changes in the fecal microbiome in constipated pediatric patients before and after antegrade continence enema placement and initiation of antegrade enemaushes. Subjects will have their microbiome sequenced prior to placement by obtaining a. Pre-antegrade continence enema placement results will be compared to fecalbtained at 0, 4, …
Approximately 1000 patients presenting with tibial shaft fractures (AO type 42) will bed prospectively in this registry. All patients are treated and followed at 6 weeks, 6hs and 1 year postoperative always following the local standard of care (routine) visithedule up to 36 months if required. Data collection includes patient …
The purpose of this collaborative CTSA application is to develop an innovative perioperativegesia platform (PPAP) to improve analgesia and reduce serious immediate andg-term adverse outcomes of perioperative opioids in children undergoing painful surgery.
Crohn's disease (CD) is a condition that causes inflammation (swelling, redness) of theg and wall of the small intestine, large intestine, or both. CD may be associated withbdominal cramps/pain, diarrhea, blood in the stool, weight loss, or delayed growth inhildren. While the exact cause of CD is not certain it …
