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Found 743 results
A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Personality traits and induced laryngeal obstruction
R
Robert Fujiki
What is the purpose of this study?Paradoxical Vocal Fold Movement (PVFM; also called Induced Laryngeal Obstruction [ILO]) consists of vocal fold adduction which occurs upon inspiration and results in dyspnea. The etiology of PVFM is often multifactorial and varied across patients. PVFM has been categorized in the literature based on …
A Global Phase 3 Open-Label Extension Study to Assess the Long-Term Safety, Tolerability, and Efficacy of Intravenous AOC 1001 for the Treatment of Myotonic Dystrophy Type 1
A
Adam Comer
To evaluate the long-term safety and tolerability of AOC 1001 in DM1 patients.THIS STUDY IS ENROLLING BY INVITATION ONLY - The study will invite participants with DM1 who completed a prior study with AOC 1001 to participate.
Evaluation of genetic mutations in African American with glaucoma associated with long anterior zonules (LAZ)
W
Weiming Mao
What is the purpose of this study?Long anterior zonules (LAZ) is the presence of the zonular fibers (a tissue that holds the lens in place) attaching to the anterior part of the lens. LAZ is a rare disease and is genetically associated with certain gene mutations. It has been reported …
Six Versus Twelve Month Surveillance Following Resection of Nonpedunculated Colorectal Polyps 20-50 mm in Size without High Grade Dysplasia (HGD)
J
John Guardiola
The primary objective of this study is to compare the efficacy of a standard 6-month initial surveillance colonoscopy versus a 12-month initial surveillance colonoscopy following successful removal of nonpedunculated adenomatous and sessile serrated colorectal polyps 20-50 mm in size without high grade dysplasia.THIS STUDY IS ENROLLING BY INVITATION ONLY - …
Optimizing Cirrhosis Emergency Care
A
Archita Desai, MD
Within our IU health system, utilizing retrospective data we developed a clinical decision instrument based on ED visits, named it as Cirrhosis Risk Instrument for Stratifying Post Emergency Department mortality (CRISPE) tool. This tool was designed to identify predictors of 14-day and 30-day mortality in individuals with cirrhosis. However, given …
Global Prospective Hemolytic Disease of the Fetus and Newborn Registry
H
Hiba Mustafa, MD
The purpose of the study is to prospectively evaluate treatment effectiveness and outcomes for alloimmunized pregnant participants and their corresponding fetuses, neonates, infants, and children at risk for HDFN in a real-world setting. This prospective registry enables the identification of risk factors, disease progression patterns, and treatment outcomes in ways …
Risk Adapted Treatment of Unilateral Favorable Histology Wilms Tumors (FHWT)
M
Marissa Just
This phase III trial studies using risk factors in determining treatment for children with favorable tissue (histology) Wilms tumors (FHWT). Wilms Tumor is the most common type of kidney cancer in children, and FHWT is the most common subtype. Previous large clinical trials have established treatment plans that are likely …
Clinical Utility Study to Determine Impact of PanCystPro Assay on Physician Decision-making in the Management of Pancreatic Cystic Lesions
M
Mohammad Al-Haddad, MD
The purpose of this research is to learn if the PanCystPro assay can help doctors in making decisions about treatment and monitoring of pancreatic cysts. The PanCystPro test measures glucose, carcinoembryonic antigen (CEA), and gastricsin biomarkers on fluid obtained from a pancreatic cyst. The test reports if the cyst fluid …
Mindfulness Based Stress Reduction Groups- Satisfaction Study
T
Tamara Hannon, MD
The purpose of this study is to provide weekly introductory mindfulness-based stress reduction sessions. Mindfulness-based stress reduction is a way to manage emotions and increases our ability to handle whatever is happening in life. The group sessions will be held virtually; and there will be separate groups for adolescents (14-18 …
A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study of the Safety, Tolerability and Efficacy of Caveolin-1-Scaffolding-Protein-Derived Peptide (LTI-03) in Patients with Idiopathic Pulmonary Fibrosis
R
Ryan Boente
This Phase 2, randomized, double-blind, placebo-controlled, multi-center study will compare the safety, tolerability, and efficacy of inhaled LTI-03 to placebo in participants diagnosed with IPF within 5 years of Screening who may be receiving standard of care (SoC) antifibrotic therapy.LTI-03 is an experimental medication breathed into the lungs using an …
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