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Found 759 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

A Safety and Feasibility Single-Arm Study of a Novel Catheter Thrombectomy Device For the Treatment of Pulmonary Embolism (ENGULF)

S
Sabah D. Butty, MD
18 years - 90 years
All genders
Interventional
What is the purpose of this study?Evaluation of initial safety and clinical feasibility of the Helo PE Thrombectomy System for thrombectomy in acute submassive pulmonary embolism (PE).PRIMARY OBJECTIVES:Composite device-related Major Adverse Event (MAE) rate, defined as any of the following events within 48 hours (+/- 24 hours) of the procedure: …
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Study of an Investigational Medication in Relapsing Multiple Sclerosis

A
Ajay Gupta
18 years - 55 years
All genders
Phase 3
Interventional
The purpose of this study is to compare the effectiveness and safety of an investigational medication to an existing treatment in adults with relapsing forms of multiple sclerosis (MS). Multiple sclerosis is a condition where the immune system mistakenly attacks the protective covering of nerves, leading to communication problems between …
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Phase III Trial of Stereotactic Radiosurgery (SRS) versus Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) for Brain Metastases from Small Cell Lung Cancer.

K
Kevin Shiue
18 years - 100 years
All genders
Phase 3
What is the purpose of this study?This phase III trial compares the effect of stereotactic radiosurgery to standard of care memantine and whole brain radiation therapy that avoids the hippocampus (the memory zone of the brain) for the treatment of small cell lung cancer that has spread to the brain. …
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Application of Cellie Coping Kits in Pediatric Patients with Eosinophilic Esophagitis (EoE)

P
Paroma Bose, MD
2 years - 18 years
All genders
Interventional
What is the purpose of this study?The aim of this study is to measure the efficacy of the Cellie Coping Kit in pediatric patients with EoE.  Furthermore, an additional aim is to determine if there is variation in the kit’s efficacy among patients being treated with diet elimination versus medications …
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Validation of Early Prognostic Data for Recovery Outcome after Stroke for Future, Higher Yield Trials

A
Ann Marie Jones
18 years - 100 years
All genders
Observational
What is the purpose of this study?Currently, 7 million US stroke survivors have significant disability, more than half with residual motor deficits. Motor function, particularly of the upper extremity (UE), is critical for regaining independence after stroke. VERIFY will validate biomarkers of upper extremity (UE) motor outcome in the acute …
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Impact of Intravitreal Pegcetacoplan Treatment on Systemic Complement Levels in Age Related Macular Degeneration: A pilot study

A
Amir Hajrasouliha
18 years - 100 years
All genders
Interventional
What is the purpose of this study?This study aims to understand how a new eye treatment, Pegcetacoplan, affects levels of certain proteins in the blood (complement proteins) that are linked to age-related macular degeneration and to measure the progression rate of the disease based on OCT landmarks using standard pretrained …
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Cervical Myelopathy in Hip Fracture Patients.

F
Flynn Rowan
50 years - 100 years
All genders
Interventional
What is the purpose of this study?Recent evidence has demonstrated a high rate of undiagnosed cervical myelopathy in patients presenting with hip fractures from a ground level fall. Identification and treatment of cervical myelopathy can help prevent falls and future fragility fractures. The purpose of this study is to screen …
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Effects of Virtual Reality Relaxation on the Anxiety Levels of Adolescents and Adults During Orthodontic Bonding: A Randomized Controlled Trial

H
Hakan Turkkahraman
13 years - 100 years
Accepts healthy volunteer
All genders
What is the purpose of this study?The purpose of this research study is to determine the effects of Virtual Reality Relaxation (VRR) on dental anxiety levels of adolescents and adults during an orthodontic bonding procedure. Specifically, we want to compare changes in the anxiety levels between patients who experienced VRR …
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Investigating Physical Activity in Hispanic or Latino/Latina Adolescent and Young Adult (AYA) Childhood Cancer Survivors

S
Sandeep Batra, MD
15 years - 20 years
All genders
This study investigates a home-based physical activity program designed for Hispanic or Latino/Latina adolescent and young adult (AYA) childhood cancer survivors. After cancer treatment, some AYA survivors may experience long-term effects like weight gain, tiredness, and reduced fitness. Hispanic or Latino/Latina survivors might face a higher risk of these effects. …
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Antibiotic Strategies for Lung Symptoms in Kids with Cystic Fibrosis

D
Don Sanders, MD
3 years - 18 years
All genders
Interventional
The purpose of this study is to investigate two antibiotic treatment strategies for managing pulmonary exacerbations (PEx) in children with cystic fibrosis (CF). Cystic fibrosis is a genetic disorder that affects the lungs and other organs. This study involves children aged 3 to 18 and examines both immediate antibiotic treatment …
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