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Found 743 results
A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Evaluation of Optilume Drug-Coated Balloon for the Endoscopic Treatment of Ureteric Strictures
M
Matthew Mellon, MD
The main objective of this clinical investigation is to assess the safety and feasibility of the Optilume DCB for treatment of ureteric strictures. Other objectives include characterizing the following through descriptive analysis: • Adverse event profile • Improvement in flank pain • Renal function changes • Improvement in hydronephrosis • Need for retreatment • Pharmacokinetics of …
Supplementation of Gut-Brain Axis (Glp-1)-Activating Carbohydrates for Increasing Satiety in Adolescents with Obesity
S
Sara Naramore
Glucagon-like peptide-1 (GLP-1) drugs have quickly become a standard treatment for adults with obesity. These drugs target the appetite control center of the brain, which slows the rate of stomach emptying, and makes a person feel full. The researchers are exploring this response in children. This study is being conducted …
Evaluation of Next Generation Sensors (Ngs) and Algorithm in Patients with Type 1 and Type 2 Diabetes
V
Viral Shah
The purpose of this study is to collect data on the performance of sensor(s) each connected to/integrated with the transmitter(s) during 7-17 days of wear (approximately 170 to 410 hours) in subjects with type 1 or type 2 diabetes, 2-80 years of age.THIS STUDY IS ENROLLING BY INVITATION ONLY
Ep0239 Sleep Disturbances, Behavior, Activities Of Daily Living, And Caregiver Burden Among Patients Diagnosed With Dravet Syndrome And Lennox-Gastaut Syndrome Initiating Treatment With Fenfluramine (Fintepla): A Prospective Multicenter Study
J
Jason Santiago
Fenfluramine (Fintepla®) is currently approved in your country for the treatment of seizures associated with Dravet syndrome (DS) and for Lennox-Gastaut syndrome (LGS). In addition to seizures, almost all patients experience multiple and significant non-seizure disorders. This study aims to describe the treatment-related impact of fenfluramine on non-seizure outcomes, ie, …
Testing the Addition of the Anti-Cancer Drug Venetoclax And/Or the Anti-Cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed Kmt2A-Rearranged or Kmt2A-Non-Rearranged Leukemia
A
Amanda J. Saraf, DO
This phase II trial tests the addition of venetoclax and/or blinatumomab to usual chemotherapy for treating infants with newly diagnosed acute lymphoblastic leukemia (ALL) with a KMT2A gene rearrangement (KMT2A-rearranged [R]) or without a KMT2A gene rearrangement (KMT2A-germline [G]). Venetoclax is in a class of medications called B-cell lymphoma-2 (Bcl-2) …
An International Pilot Study of Chemotherapy and Tyrosine Kinase Inhibitors with Blinatumomab in Patients with Newly-Diagnosed Philadelphia Chromosome-Positive or Abl-Class Philadelphia Chromosome-Like B-Cell Acute Lymphoblastic Leukemia
S
Sandeep Batra, MD
This phase III trial compares the effect of the combination of blinatumomab with dasatinib or imatinib and standard chemotherapy versus dasatinib or imatinib and standard chemotherapy for treating patients with Philadelphia chromosome positive (PH+) or ABL-class Philadelphia chromosome-like (Ph-Like) B-Cell acute lymphoblastic leukemia (B-ALL). Blinatumomab is a bispecific antibody that …
A Clinical Efficacy and Safety Study of OHB-607 in Preventing Bronchopulmonary Dysplasia in Extremely Premature Infants
A
Anna Elizabeth Thomas
The purpose of this study is to determine if an investigational drug can prevent Bronchopulmonary Dysplasia, reducing the burden of chronic lung disease in extremely premature infants, as compared to extremely premature infants receiving standard neonatal care alone.THIS STUDY IS ENROLLING BY INVITATION ONLY
Investigating Methods for Child Mental Health Conditions
R
Rebecca McNally Keehn
The purpose of the study is to learn more about children’s mental health. We are hoping to better understand how to predict and diagnose common mental health diagnoses in children.THIS STUDY IS ENROLLING BY INVITATION ONLY - A two-step process will be used to identify and screen potential participants. In …
Twins With Specific Vs. Traditional Fetal Growth Charts (Twist): A Randomized Controlled Trial
H
Hiba Mustafa, MD
This study will compare two different ways of monitoring growth in twin pregnancies. One method uses growth charts designed for single babies, while the other uses charts made specifically for twins. We want to find out which method better identifies babies who are truly at risk and helps avoid unnecessary …
A Phase Iii, Randomised, Double-Blind, Placebo-Controlled, Event-Driven Study to Assess the Efficacy, Safety and Tolerability of Baxdrostat in Combination With Dapagliflozin Compared With Dapagliflozin Alone on Renal Outcomes and Cardiovascular Mortality in Participants With Chronic Kidney Disease and High Blood Pressure
S
Sharon Moe, MD
The purpose of this study is to investigate the efficacy, safety, and tolerability of baxdrostat in combination with dapagliflozin, compared with placebo and dapagliflozin, in reducing the risk of the composite of > 50% decline in eGFR, kidney failure, or CV death, in individuals with CKD and HTN.THIS STUDY IS …
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