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Found 758 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Study on the Effectiveness of Investigational Medication Versus Standard Treatment for Glioblastoma, a Type of Brain Cancer

K
Kathryn Nevel
18 years - 100 years
All genders
Phase 3
This study investigates the effectiveness and safety of an investigational medication compared to a standard treatment in adults with newly-diagnosed glioblastoma. Glioblastoma is a type of brain cancer. The study aims to see if the investigational medication can improve the time patients live without the cancer getting worse and overall …
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Clinical Trial Designed to Assess the Safety and Effectiveness of the KOKO Device In Treating Primary Abnormal Postpartum Uterine Bleeding ("APUB") or Hemorrhage ("PPH")

C
Christina M. Scifres, MD
18 years - 100 years
Female
Interventional
What is the purpose of this study?The sponsor of this research study, KOKO Medical Inc, is evaluating a medical device to control and treat abnormal postpartum uterine bleeding or hemorrhage (excessive bleeding). The device is called the KOKO device and its use in this study is experimental. The purpose of …
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Study on Investigational Medication for Alzheimer's Disease Treatment

J
Jared Brosch, MD
60 years - 85 years
All genders
Phase 1/2
This study investigates the use of an investigational medication for treating Alzheimer's disease, a condition that affects memory and thinking. The purpose of this study is to collect data on how well the investigational medication, which is a form of vitamin B3, reaches the spinal fluid. This will help understand …
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Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation (DIAN-TU) (DIAN-TU)

J
Jared Brosch, MD
18 years - 80 years
All genders
Phase 2/3
Interventional
What is the purpose of this study?To assess the safety, tolerability, biomarker, cognitive, and clinical efficacy of investigational products in participants with an Alzheimer's disease-causing mutation by determining if treatment with the study drug improves disease-related biomarkers and slows the rate of progression of cognitive or clinical impairment.THIS STUDY IS …
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Studying the Safety and Effectiveness of Bladder-Administered Therapy for BCG-Unresponsive Bladder Cancer

H
Hristos Kaimakliotis, MD
18 years - 100 years
All genders
Phase 2
This study investigates the safety and efficacy of intravesical nadofaragene firadenovec, either alone or in combination with chemotherapy or immunotherapy, in patients with high-grade Bacillus Calmette-Guerin (BCG) unresponsive non-muscle invasive bladder cancer (NMIBC). NMIBC is a type of bladder cancer that has not spread into the muscle layer of the …
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Use of Point-of-Care Ultrasound (POCUS) for the Diagnosis of Acute Chest Syndrome in Patients with Sickle Cell Disease

S
Seethal Jacob, MD
25 years or below
All genders
Observational
What is the purpose of this study?Acute chest syndrome (ACS) is a complication of sickle cell disease requiring hospitalization that is characterized by symptoms of fever, low oxygen levels or difficulty breathing in the setting of a new lung finding on chest x-ray. Chest x-rays have historically been used as …
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Study of Investigational Medication in Individuals with Liver Disease

R
Raj Vuppalanchi, MD
18 years - 80 years
All genders
Phase 1
Interventional
This study investigates the effects of an investigational medication on people with moderate liver problems and cirrhosis caused by a liver condition called cholestatic liver disease. The purpose is to understand how the body processes the medication and how safe it is for these individuals. Cirrhosis is a condition where …
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Patient-Centered Clinical Effectiveness Research Priorities for Transitioning Children with Cancer from Hospital to Home

E
Emily Mueller, MD
17 years or below
All genders
What is the purpose of this study?The purpose of this study is to study the transition from an inpatient hospital admission to being at home by engaging with caregivers (parents, legal guardians, etc) of children of cancer as well as with healthcare providers that participate in this process with the …
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Project ADAM: Long-Term Outcomes

A
Adam Kean, MD
99 years or below
All genders
Observational
The purpose is to establish a database of SCA (Sudden Cardiac Arrest) victims to better characterize the predisposing factors, causes, emergency response, diagnoses, procedures, and long-term outcomes surrounding this life-threatening emergency. Expanding to a national scope rather than isolated communities or regional areas, will change the way we view SCA …
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CHronic nonbacterial Osteomyelitis International Registry (CHOIR)

M
Melissa Oliver, MD
100 years or below
All genders
Observational
What is the purpose of this study?The objective of the study is to establish a prospective disease registry for chronic recurrent multifocal osteomyelitis (CRMO)/chronic nonbacterial osteomyelitis (CNO) in order to investigate the natural history of the disease and the responses of patients to different clinical managements over 5 yearsTHIS STUDY …
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