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Found 768 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

A Randomized, Two-period Crossover Study to Demonstrate the Comparability of Pharmacokinetics of Subcutaneous Ianalumab Between 2mL Auto-injector/2mL Pre-filled Syringe With 1 mL Pre-filled Syringe in Adult Participants With Autoimmune Disease

D
Domenick Zero, DDS, MS
18 years - 70 years
All genders
Phase 2
Interventional
What is the purpose of this study?The purpose of this study is to demonstrate the comparability of ianalumab exposure following the sub-cutaneous (s.c.) administration of one injection of 300 mg/2 mL auto-injector (AI) versus two injections of 150 mg/1 mL pre-filled syringe (PFS), and to evaluate the safety and tolerability …
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Investigating Long-Term Effects of Investigational Treatment in Phenylketonuria (PKU)

M
Melissa Lah, MD
100 years or below
All genders
Observational
This study investigates the effects of long-term treatment on people with phenylketonuria (PKU), a condition where the body cannot break down an amino acid called phenylalanine, which can lead to harmful levels in the body. The purpose of this study is to evaluate immune and inflammatory responses in participants receiving …
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Study on Investigational Medication for Candidemia and Invasive Candidiasis

N
Nicolas Barros, MD
18 years - 100 years
All genders
Phase 3
Interventional
This study investigates the effects and safety of an investigational medication for treating candidemia and invasive candidiasis, which are serious fungal infections caused by Candida species. Candidemia is a bloodstream infection, while invasive candidiasis occurs when the infection spreads beyond the bloodstream to other parts of the body.Participants will receive …
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Investigational Study of Maintenance Therapy in Ovarian Cancer with HER2 Protein

J
Jessica Parker
18 years - 100 years
Female
Phase 3
This study investigates the effectiveness of an investigational medication in combination with another medication compared to the other medication alone as a first-line maintenance therapy for patients with HER2-expressing ovarian cancer. HER2 is a protein that can affect the growth of some cancer cells. This study focuses on advanced high-grade …
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Investigating the Safety of an Investigational Treatment for a Type of Cancer Affecting White Blood Cells

H
Huda Salman
18 years - 100 years
All genders
Phase 1
This study investigates the safety of an investigational treatment using special immune cells called CAR-T cells for people with certain B cell cancers. B cell malignancies are cancers that affect a type of white blood cell. The study includes participants whose cancer has returned or not responded to previous treatments. …
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Characterization of the neural correlates of anesthetic-induced intraoperative dream states using stereoelectroencephalography.

D
David Purger
18 years - 100 years
All genders
Observational
What is the purpose of this study?Dreams experienced during emergence from anesthesia have been associated with improvement in trauma-related psychiatric disorders. This study aims to characterize the brain network activity patterns associated with anesthetic-induced intraoperative dreams to gain insight into the underlying mechanisms of the phenomenon and its potential therapeutic …
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The Effect of Lower Extremity Fracture Non-union on Gait

Y
Yohan Jang
18 years - 85 years
All genders
Observational
What is the purpose of this study?This study aims to understand how lower leg fractures that don’t heal properly affect walking speed. It also seeks to verify if the Apple iPhone can accurately measure walking speed and other gait characteristics in people with these injuries.THIS STUDY IS ENROLLING BY INVITATION …
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Investigating a Combination Therapy for Advanced Breast Cancer

K
Kathy Miller, MD
18 years - 100 years
All genders
Phase 1
This study investigates the safety and effects of a combination treatment for locally advanced or metastatic breast cancer. Breast cancer is a disease where cells in the breast grow out of control. This study looks at an investigational medication made from the patient's own T cells, which are a type …
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Study of Investigational Medication vs Standard Treatments in Cancer That Has Spread

N
Nabil Adra, MD
18 years - 100 years
Male
Phase 3
This study investigates the treatment of metastatic castration-resistant prostate cancer (mCRPC), which is a type of cancer that continues to grow even when the amount of testosterone in the body is reduced to very low levels. The purpose of this study is to compare overall survival between participants receiving an …
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Study on Investigational Medication for Crohn's Disease

16 years - 80 years
All genders
Phase 3
Interventional
This study investigates the use of an investigational medication for people with moderately to severely active Crohn's disease, a condition that causes inflammation in the digestive tract. The investigational medication is a type of antibody that targets a protein involved in the immune response in the gut. The study aims …
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