A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Why is this study being done?In some people, the liver makes an abnormal version of the alpha-1 antitrypsin (AAT) protein, called Z-AAT. Making an abnormal version of the AAT protein can result in liver disease as Z-AAT builds up in liver cells, which leads to liver problems such as liver …
Why is this study being done?The study will be a prospective, pragmatic, randomized clinical trial ofhe comparative effectiveness of an initial strategy for the treatment of uncomplicated type B aortic dissection (uTBAD). The goal of this clinical trial is to determine whether an upfront invasive strategy of TEVAR plus medical …
This study investigates the safety and effectiveness of an investigational vascular stent system for treating peripheral artery disease. Peripheral artery disease is a condition where the arteries in the legs become narrowed or blocked, which can cause pain and other symptoms. The investigational stent will be used to treat blockages …
What is the purpose of this study?The primary objective of this study is to evaluate the effect of romosozumab treatment for 12-months compared with bisphosphonate(s) on the number of clinical fractures at 12-months; the number of any fractures at 12-months and change in lumbar spine bone mineral density (BMD) Z-score …
What is the purpose of this study?The study will evaluate the efficacy and safety of chronic oral levosimendan compared with placebo in PH-HFpEF subjects. This subject population represents a large and growing group with no established therapies to treat their PVD and RV dysfunction. Levosimendan and its prolonged active metabolite, …
What is the purpose of this study?This study is being done to find out how safe and how well the drug Tapinarof (VTAMA) works for stopping or treating palmoplantar keratoderma, which is a condition characterized by thickened skin on your palms and soles. Tapinarof, used as a topical 1% cream, …
What is the purpose of this study?Atrial fibrillation/ atrial flutter are common irregular heart beats or arrhythmias that causes quivering of the heart and sometimes a very fast heart rate and can lead to blood clots and strokes. Many of the current drugs on the market used to treat atrial …
What is the purpose of this study?The OnPrime study is a multi-center, randomized open-label phase 3 study evaluating the safety and efficacy of Olvi-Vec followed by platinum-doublet chemotherapy and bevacizumab compared to the Active Comparator Arm with Physician's Choice of chemotherapy and bevacizumab in women diagnosed with platinum-resistant/refractory ovarian cancer …
This study investigates the use of circulating tumor DNA (ctDNA) to personalize treatment for patients with stage III non-small cell lung cancer (NSCLC). The purpose is to use ctDNA analysis to guide therapy decisions, instead of relying solely on clinical or radiographic evidence of disease. This approach aims to tailor …
What is the purpose of this study?This study seeks to explore if GT, given its unique radiobiological and physical characteristics, may permit safe dose escalation and intensification and thereby provide a benefit to newly diagnosed GBM patients in terms of OS and LC when incorporated into the framework of the …
