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Found 768 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

A PHASE 3 RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY TO EVALUATE THE EFFICACY AND SAFETY OF DNTH103 IN ADULTS WITH CHRONIC INFLAMMATORY DEMYELINATING POLYNEUROPATHY (CAPTIVATE)

C
Cynthia Bodkin, MD
18 years - 75 years
All genders
Phase 3
Interventional
What is the purpose of this study?Study DNTH103-CIDP-301 is a global, multicenter, randomized, double-blind, placebo-controlled trial designedto evaluate the efficacy and safety of DNTH103 in adults with chronic inflammatory demyelinating polyneuropathy (CIDP). THIS STUDY IS ENROLLING BY INVITATION ONLY   
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A Safety and Feasibility Single-Arm Study of a Novel Catheter Thrombectomy Device For the Treatment of Pulmonary Embolism (ENGULF)

S
Sabah D. Butty, MD
18 years - 90 years
All genders
Interventional
What is the purpose of this study?Evaluation of initial safety and clinical feasibility of the Helo PE Thrombectomy System for thrombectomy in acute submassive pulmonary embolism (PE).PRIMARY OBJECTIVES:Composite device-related Major Adverse Event (MAE) rate, defined as any of the following events within 48 hours (+/- 24 hours) of the procedure: …
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Study of an Investigational Medication in Relapsing Multiple Sclerosis

A
Ajay Gupta
18 years - 55 years
All genders
Phase 3
Interventional
The purpose of this study is to compare the effectiveness and safety of an investigational medication to an existing treatment in adults with relapsing forms of multiple sclerosis (MS). Multiple sclerosis is a condition where the immune system mistakenly attacks the protective covering of nerves, leading to communication problems between …
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Phase III Trial of Stereotactic Radiosurgery (SRS) versus Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) for Brain Metastases from Small Cell Lung Cancer.

K
Kevin Shiue
18 years - 100 years
All genders
Phase 3
What is the purpose of this study?This phase III trial compares the effect of stereotactic radiosurgery to standard of care memantine and whole brain radiation therapy that avoids the hippocampus (the memory zone of the brain) for the treatment of small cell lung cancer that has spread to the brain. …
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Application of Cellie Coping Kits in Pediatric Patients with Eosinophilic Esophagitis (EoE)

P
Paroma Bose, MD
2 years - 18 years
All genders
Interventional
What is the purpose of this study?The aim of this study is to measure the efficacy of the Cellie Coping Kit in pediatric patients with EoE.  Furthermore, an additional aim is to determine if there is variation in the kit’s efficacy among patients being treated with diet elimination versus medications …
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Study of Investigational Medication for KRAS Mutant Solid Tumors

G
Greg Durm, MD
18 years - 100 years
All genders
Phase 1/2
This study investigates an investigational medication for people with solid tumors that have specific KRAS mutations. These mutations are changes in a gene that can affect how cells grow. The purpose of this study is to understand if the investigational medication is safe and can be tolerated by patients with …
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Validation of Early Prognostic Data for Recovery Outcome after Stroke for Future, Higher Yield Trials

A
Ann Marie Jones
18 years - 100 years
All genders
Observational
What is the purpose of this study?Currently, 7 million US stroke survivors have significant disability, more than half with residual motor deficits. Motor function, particularly of the upper extremity (UE), is critical for regaining independence after stroke. VERIFY will validate biomarkers of upper extremity (UE) motor outcome in the acute …
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Impact of Intravitreal Pegcetacoplan Treatment on Systemic Complement Levels in Age Related Macular Degeneration: A pilot study

A
Amir Hajrasouliha
18 years - 100 years
All genders
Interventional
What is the purpose of this study?This study aims to understand how a new eye treatment, Pegcetacoplan, affects levels of certain proteins in the blood (complement proteins) that are linked to age-related macular degeneration and to measure the progression rate of the disease based on OCT landmarks using standard pretrained …
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Cervical Myelopathy in Hip Fracture Patients.

F
Flynn Rowan
50 years - 100 years
All genders
Interventional
What is the purpose of this study?Recent evidence has demonstrated a high rate of undiagnosed cervical myelopathy in patients presenting with hip fractures from a ground level fall. Identification and treatment of cervical myelopathy can help prevent falls and future fragility fractures. The purpose of this study is to screen …
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ONCOLOGY CLINICIANS PERSPECTIVES ON TREATMENT DECISION-MAKING AND THE ACCEPTABILITY AND USABILITY OF THE INTERACTIVE WEB-ENABLED COMMUNICATION RESOURCES OF THE CLL/SLL CARE ROAD MAP

L
Larry Cripe, MD
18 years - 100 years
All genders
What is the purpose of this study?To characterize the way in which oncologists, oncology nurses, and oncology pharmacists evaluate the treatment options for patients with CLL/SLL and engage or support patients in shared decision-making.To test the acceptability and usability of the interactive web-enabled communication and decision-making resources of the CLL/SLL …
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