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Found 742 results

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Prevalence and Longitudinal Course of Depression, Anxiety, and Behavior Problems in Children with Cystic Fibrosis Under 12 Years of Age

E
Emma Tillman
18 months - 11 years
All genders
Observational
This is a longitudinal, observational epidemiological study designed to estimate the prevalence of depression, anxiety, and behavior problems in children ages 18 months through 11 years with cystic fibrosis (CF). THIS STUDY IS ENROLLING BY INVITATION ONLY

A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study Evaluating The Safety And Efficacy Of Efruxifermin In Subjects With Non-Cirrhotic Nonalcoholic Steatohepatitis (Nash)/Metabolic Dysfunction-Associated Steatohepatitis (Mash) And Fibrosis

R
Raj Vuppalanchi, MD
18 years - 80 years
All genders
Phase 3
Interventional
This is a multi-center evaluation of efruxifermin (EFX) in a randomized, double-blind, placebo-controlled study in subjects with non-cirrhotic NASH/MASH and fibrosis stage 2 or 3 (F2 or F3).Study goals:To evaluate the effect of EFX compared to placebo on achieving NASH/MASH resolution AND fibrosis regression at Week 52 (in Cohort 1 …

A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Safety and Efficacy of Efruxifermin in Subjects With Compensated Cirrohosis Due to Nash/Mash

R
Raj Vuppalanchi, MD
18 years - 80 years
All genders
Phase 3
Interventional
This is a multi-center evaluation of efruxifermin (EFX) in a randomized, double-blind, placebo-controlled study in subjects with compensated cirrhosis due to NASH/MASH.THIS STUDY IS ENROLLING BY INVITATION ONLY

Research in Arthroscopy of Meniscus in Pediatric Populations (Rampp)

G
Gunnar Tysklind
19 years or below
All genders
Observational
The goal of this study is to develop a multi-center registry detailing long-term clinical and patient-reported outcomes in pediatric patients (THIS STUDY IS ENROLLING BY INVITATION ONLY - Participants will be enrolled either at their pre-operative clinic visit or on the day of their surgery in the preoperative holding area …

Ketamine Add-On Therapy for Established Status Epilepticus Treatment Trial

P
Paul Musey, MD
1 years or above
All genders
Interventional
The goal of this clinical trial is to determine if treatment of patients with two doses of ketamine plus levetiracetam versus levetiracetam alone leads to more effective control of status epilepticus.THIS STUDY IS ENROLLING BY INVITATION ONLY

A 52-Week, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Group Sequential Study to Evaluate the Efficacy and Safety of Rilzabrutinib in Patients Aged 10 to 65 Years With Sickle-Cell Disease (Libra)

S
Seethal Jacob, MD
10 years - 65 years
All genders
Interventional
This is a multicenter, randomized, double-blind, placebo-controlled, parallel-group, group-sequential study (Part A), followed by an open-label LTE period (Part B) to investigate the efficacy, and safety of rilzabrutinib in participants with sickle-cell disease (SCD).THIS STUDY IS ENROLLING BY INVITATION ONLY

A Phase 2 Study of Mutant-Selective Pi3Kα Inhibitor, Rly-2608, in Adults and Children with Pik3Ca Related Overgrowth Spectrum and Malformations Driven by Pik3Ca Mutation

R
Rachael Schulte
2 years or above
All genders
Phase 2
Interventional
This is a 3-part Phase 2 randomized study evaluating the safety and efficacy of the mutant-selective PI3Kα inhibitor, RLY-2608, in adults and children with PIK3CA Related Overgrowth Spectrum (PROS) and malformations driven by PIK3CA mutation. THIS STUDY IS ENROLLING BY INVITATION ONLY

A Prospective, Multi-Center, Open-Label Clinical Investigation and Longitudinal Registry of the Cleaner Vac® Thrombectomy System for Peripheral Venous Thrombus Removal, Including a Subgroup Analysis of Patients With Lower Extremity Proximal Deep Vein Thrombosis

S
Sabah D. Butty, MD
18 years - 100 years
All genders
Observational
The primary objective of this clinical investigation is to evaluate the safety and effectiveness of the Cleaner Vac Thrombectomy System for the removal of thrombus in the peripheral venous vasculature in a real-world, all-comers population. This prospective, multi-center, open-label study will assess clinical outcomes, device performance, and procedural success across …

Supraglottic Airway for Resuscitation Trial

E
Elizabeth Wetzel
34 weeks - 1 year
All genders
Interventional
The SUGAR Trial is a cluster-randomized, implementation trial evaluating two strategies to promote the use of early supraglottic airway (SA) rescue during neonatal resuscitation. No direct patient contact or intervention will occur, and all newborn data collection is covered under a waiver of consent and HIPAA authorization. THIS STUDY IS ENROLLING …

Characteristics And Clinical Course Of Disease In Participants With Cardiomyopathy Associated With Friedreich Ataxia (Clarity-Fa)

R
R. Mark Payne, MD
6 years - 17 years
All genders
Observational
Study LX2006-02 is a prospective, longitudinal, low-intervention, multicenter, global study aimed at characterizing the nature and rate of cardiac disease progression in participants with genetically confirmed FA-CM.THIS STUDY IS ENROLLING BY INVITATION ONLY -  Participants with a confirmed diagnosis of FA-CM, specifically identified by LVH by cMRI), will be contacted …
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