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Found 742 results
A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Pharmacokinetics and Placental Transfer of Caffeine: a Pilot Study of Antenatal Caffeine Administration Across the Second and Third Trimester of Pregnancy
A
Anna Elizabeth Thomas
Caffeine therapy is typically given to an infant to prevent apnea of prematurity shortly after birth. It is possible that giving caffeine therapy earlier, to the fetus in utero, that there is a more pronounced benefit and improvement in neonatal outcomes. This study is evaluating whether giving caffeine citrate to …
An Observational Study of Lung Screening in Individuals at High Risk for Lung Cancer Who Do Not Meet the Uspstf Criteria
J
Julian Marin Acevedo
Study purposse: Describe the demographics, risk factors for lung cancer, and baseline Lung Rads score of individuals enrolled in this observational study. Using descriptive statistics, compare the demographics and Lung Rads score of the participants enrolled in this study with those participating in the NLST and NELSON studies. Using descriptive …
Bowel Continence Across the Lifespan in People with Spina Bifida
K
Konrad Szymanski, MD
The purpose of this study is to compare these two types of enema programs in children and adults with spina bifida across the United States. We want to learn about how well enemas work to prevent bowel accidents and other bowel problems, how well people can do their enemas on …
Post-Approval Study of the Neuspera Sacral Neuromodulation (Snm) System in Patients with Symptoms of Urinary Urgency Incontinence (Uui)
C
Charles Powell, MD
Prospective, multi-center, single-arm, post-approval study is designed to assess the long-term safety and efficacy data of the Neuspera Sacral Neuromodulation (SNM) System following commercial approval of the Neuspera SNM System.Participants in this study received intervention/implanted in Phase I or Phase II of the Neuspera SANS_UUI (NSM-004) Study.THIS STUDY IS ENROLLING …
Slowly Reloading To Prevent (Stop) Ulcer Recurrence Following Plantar Diabetic Foot Ulcers
M
Mithun Sinha
There is an immediate need for data informing the role of daily loading in DFU recurrence, and also an immediate need for a clinical approach to mitigate risk in a way that is feasible for both facilities and patients. This research will provide the requisite information to develop targets for …
A Randomised, Double-Blind, Placebo-Controlled Trial with an Open-Label Extension to Assess the Pharmacokinetics, Safety, and Efficacy of Empagliflozin Tablets in Paediatric Patients with Chronic Kidney Disease (Empa-Kidney Kids)
M
Myda Khalid
This study is open to children aged 2 to 17 with chronic kidney disease (CKD). The purpose of this study is to find out if a medicine called empagliflozin helps children and adolescents with CKD. Other goals of the study are to find out how empagliflozin is tolerated and handled …
A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)
S
Sandeep Batra, MD
This phase II trial studies the effect of nivolumab in combination with blinatumomab compared to blinatumomab alone in treating patients with B-cell acute lymphoblastic leukemia (B-ALL) that has come back (relapsed). Down syndrome patients with relapsed B-ALL are included in this study. Blinatumomab is an antibody, which is a protein …
Studying DNA Damage and Repair in Lung Diseases
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Catherine Sears, MD
We will collect cells from the airways and blood of adult patients undergoing clinical bronchoscopy to study how these cells repair DNA after exposure to airborne pollutants like tobacco smoke. We will grow these airway cells in a lab setting to create a 3D model of the lung's surface and …
Multi-Modal Large Language Model-Empowered Talk Therapy for Older Adults with ADRD
M
Malaz Boustani, MD
The purpose of this study is to test the usefulness and the effect of the Smart Virtual Reminiscence (SVR) therapy intervention on the Behavioral and Psychological Symptoms of Dementia (BPSD) of patients with Alzheimer’s Disease and Related Dementias (ADRD). BPSD refers to changes in behavior and mood that often occur in dementia, …
A Randomized Phase 1/2 Trial of Low Dose Anti-Thymocyte Globulin (Atg) with Subsequent Adalimumab or Verapamil in New Onset Type 1 Diabetes (Wave T1D)
H
Hannah Lease
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Linda DiMeglio, MD
The purpose of this study is to learn if a low dose of a medication called ATG, combined with either Adalimumab or Verapamil, can help the pancreas continue to make insulin for a longer time which may also help to control blood glucose. This multi-center randomized controlled trial will assess …
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