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Found 768 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Comparing Surgical and Non-Surgical Treatments for Pelvis Fractures

Y
Yohan Jang
60 years - 100 years
All genders
Interventional
This study investigates the effectiveness of early surgical treatment compared to non-surgical care with early rehabilitation for pelvis fractures. A pelvis fracture is a break in one or more of the bones of the pelvis. The study focuses on patients aged 60 years or older with a specific type of …
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Total Shoulder Arthroplasty Multi-Center Registry study

M
Mark Dillon
18 years - 100 years
All genders
Observational
What is the purpose of this study?This study is an ongoing, non-randomized, multi-center, prospective registry utilizing primary or revision shoulder arthroplasty implants.  Subjects will be treated according to standard of care at each center. The objective of the study is a multi-center prospective registry to collect clinical outcomes of anatomic …
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Feasibility of the Venous Excess in Ultrasound Score and its correlation with elevated CVP and RAP in Pediatric CVICU patients

M
Michael David Lintner-Rivera
17 years or below
All genders
Observational
What is the purpose of this study?There is extremely limited knowledge of the applicability of VEXUS in critically ill children. VExUS was recently evaluated in a cohort of pediatric ICU patients and was found to correlate well with CVP measurements. (11) To date, there have been no studies determining the …
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Study on the Effectiveness of Investigational Medication Versus Standard Treatment for Glioblastoma, a Type of Brain Cancer

K
Kathryn Nevel
18 years - 100 years
All genders
Phase 3
This study investigates the effectiveness and safety of an investigational medication compared to a standard treatment in adults with newly-diagnosed glioblastoma. Glioblastoma is a type of brain cancer. The study aims to see if the investigational medication can improve the time patients live without the cancer getting worse and overall …
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Clinical Trial Designed to Assess the Safety and Effectiveness of the KOKO Device In Treating Primary Abnormal Postpartum Uterine Bleeding ("APUB") or Hemorrhage ("PPH")

C
Christina M. Scifres, MD
18 years - 100 years
Female
Interventional
What is the purpose of this study?The sponsor of this research study, KOKO Medical Inc, is evaluating a medical device to control and treat abnormal postpartum uterine bleeding or hemorrhage (excessive bleeding). The device is called the KOKO device and its use in this study is experimental. The purpose of …
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Nicotinic Acid for the treatment of Alzheimer's Disease Protocol Type: Interventional

J
Jared Brosch, MD
60 years - 85 years
All genders
Phase 1/2
What is the purpose of this study?The primary objective of this study is to collect data on the penetration of commercially available, FDA approved, extended-release niacin into the spinal fluid. One dose of 500 mg nicotinic acid will be used (in addition to placebo) to build a dose response curve …
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Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation (DIAN-TU) (DIAN-TU)

J
Jared Brosch, MD
18 years - 80 years
All genders
Phase 2/3
Interventional
What is the purpose of this study?To assess the safety, tolerability, biomarker, cognitive, and clinical efficacy of investigational products in participants with an Alzheimer's disease-causing mutation by determining if treatment with the study drug improves disease-related biomarkers and slows the rate of progression of cognitive or clinical impairment.THIS STUDY IS …
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Studying the Safety and Effectiveness of Bladder-Administered Therapy for BCG-Unresponsive Bladder Cancer

H
Hristos Kaimakliotis, MD
18 years - 100 years
All genders
Phase 2
This study investigates the safety and efficacy of intravesical nadofaragene firadenovec, either alone or in combination with chemotherapy or immunotherapy, in patients with high-grade Bacillus Calmette-Guerin (BCG) unresponsive non-muscle invasive bladder cancer (NMIBC). NMIBC is a type of bladder cancer that has not spread into the muscle layer of the …
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Use of Point-of-Care Ultrasound (POCUS) for the Diagnosis of Acute Chest Syndrome in Patients with Sickle Cell Disease

S
Seethal Jacob, MD
25 years or below
All genders
Observational
What is the purpose of this study?Acute chest syndrome (ACS) is a complication of sickle cell disease requiring hospitalization that is characterized by symptoms of fever, low oxygen levels or difficulty breathing in the setting of a new lung finding on chest x-ray. Chest x-rays have historically been used as …
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A phase 1, open-label, single arm study to evaluate pharmacokinetics, safety, and tolerability of Saroglitazar Magnesium dosed on alternate days in subjects having moderate hepatic impairment with cirrhosis due to cholestatic liver disease

R
Raj Vuppalanchi, MD
18 years - 80 years
All genders
Phase 1
Interventional
To evaluate PK after Saroglitazar Magnesium 1 mg dose on alternate days in subjects with moderate hepatic impairment with cirrhosis due to CLD based on Child-Pugh-Turcotte (CPT) score.To assess safety and tolerability of Sa-roglitazar Magnesium 1 mg dose on alter-nate days in subjects with moderate hepatic impairment with cirrhosis due …
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