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Found 716 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Topical Antibiotic Therapy to Reduce Infection After Operative Treatment of Fractures at High Risk of Infection: TOBRA

B
Brian Mullis, MD
18-80 years
All genders
Phase 3
Interventional
The overall objective is to compare the effect of Vancomycin and Tobramycin powder combined (treatment) to Vancomycin powder (control) in the reduction of post-fixation infections ofbial plateau and tibial pilon fractures at high risk of infection (collectively consideredhe "study injuries").
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Intensive Glycemic Targets in Overweight and Obese Women With Gestational Diabetes (iGDM)

C
Christina M. Scifres, MD
18-45 years
Female
Interventional
This is a multicenter randomized clinical trial of 828 overweight and obese individuals with gestational diabetes designed to compare standard to intensive glycemic targets.
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Bevacizumab Treatment For Posterior Zone I ROP (ROP4)

K
Kathryn Haider, MD
6 years and younger
All genders
Phase 2
Interventional
Type 1 retinopathy of prematurity in zone I represents the most severe type of ROP and hashe worst prognosis. It is unknown whether low-dose bevacizumab will be successful in thesevere cases. Also unknown is the timing and extent of peripheral retinal vascularizationw-dose bevacizumab compared with the standard dose. The current …
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Chronic Venous Thrombosis: Relief With Adjunctive Catheter-Directed Therapy (The C-TRACT Trial) (C-TRACT)

S
Sabah D. Butty, MD
18 years and older
All genders
Interventional
The purpose of this study is to determine if the use of image-guided, endovascular therapy (EVT) is an effective strategy with which to reduce Post Thrombotic Syndrome (PTS) diseaseverity and improve quality of life in patients with established disabling iliac-obstructivehrombotic syndrome (DIO-PTS).
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Biomarker of Diabetic Retinopathy

A
Ashay D. Bhatwadekar, PhD, MPHARM
18 years and older
All genders
Observational
Diabetic retinopathy (DR) is a complication of diabetes in which blood vessels supplying blood to the back of the eye (retina) are dysfunctional. This can lead to an improper supplyygen and nutrients to the retinal tissue, or it may trigger the formation of new blood vessels in response to the …
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A Phase II Trial of Cabozantinib With Patients With Refractory GCTs

N
Nabil Adra, MD
All genders
Phase 2
Interventional
The purpose of the CTO-IUSCCC-0752 study is to investigate the use of Cabozantinib forwith incurable, refractory germ cell tumors. Patients will be treated until evidencedisease progression, non-compliance with study protocol, unacceptable major toxicity, atubject's own request for withdrawal, or if the study closes for any reason.
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ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)

D
David Clark
18 years and older
Accepts healthy volunteer
All genders
ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD) represents thezed integration of ARTFL (U54 NS092089; funded through 2019) and LEFFTDS (U01 AG045390; funded through 2019) as a single North American research consortium to study FTLD2019 and beyond.
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Oral Ifetroban in Subjects With Duchenne Muscular Dystrophy (DMD)

J
John Parent, MD
7 years and older
Male
Phase 2
Interventional
Duchenne muscular dystrophy (DMD) is a devastating X-linked disease which leads to loss ofbulation between ages 7 and 13, respiratory failure and cardiomyopathy (CM) at any age, andvitably premature death of affected young men in their late twenties. DMD is the mostgenetic disorder diagnosed in childhood. It affects approximately 1 …
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Letrozole With or Without Paclitaxel and Carboplatin in Treating Patients With Stage II-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

L
Lisa Landrum, MD, PhD, MS
18 years and older
Female
Phase 3
Interventional
This phase III trial studies how well letrozole with or without paclitaxel and carboplatin works in treating patients with stage II-IV low-grade serous carcinoma of the ovary,ube, or peritoneum. Letrozole is an enzyme inhibitor that lowers the amount ofgen made by the body which in turn may stop the growth …
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A Study to Assess the Long-Term Safety and Efficacy of Eplontersen (Formerly Known as ION-682884, IONIS-TTR-LRx and AKCEA-TTR-LRx) in Patients With Hereditary Transthyretin-Mediated Amyloid Polyneuropathy

N
Noel Dasgupta
18 years and older
All genders
Phase 3
Interventional
The purpose of this study is to evaluate the safety and tolerability of extended dosing withwith hereditary transthyretin-mediated amyloid polyneuropathy (hATTR-PN).
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