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Found 742 results

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

A Phase 1B/2A Double Blind, Placebo Controlled Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Efficacy of Cnp-103 in Subjects Ages 12-35 With Recent Onset Stage 3 Type 1 Diabetes

L
Linda DiMeglio, MD
12 years - 35 years
All genders
Phase 1/2
Interventional
This study is a Phase 1b/2a First-in-Human (FIH) clinical trial to assess the safety, tolerability, pharmacodynamics (PD), and efficacy of multiple ascending doses of CNP-103. THIS STUDY IS ENROLLING BY INVITATION ONLY

Efficacy And Safety Of Medtronic 780G Automated Insulin Delivery System In Adults With Type 1 Diabetes And Gastroparesis

V
Viral Shah
18 years - 100 years
All genders
Interventional
The primary objective of this research is to study efficacy of Medtronic 780 G system in patients with type 1 Diabetes and gastroparesis (slow gastric emptying) compared to usual care (either multiple daily insulin injections or non Medtronic insulin pump therapy).THIS STUDY IS ENROLLING BY INVITATION ONLY - Study team …

S1703 Serum Tumor Marker Directed Disease Monitoring in Patients With Hormone Receptor Positive Her2 Negative Metastatic Breast Cancer

J
Jonathan L. Berkowitz, MD, PhD
18 years or above
All genders
Interventional
This randomized research trial studies how well serum tumor marker directed disease monitoring works in monitoring patients with hormone receptor positive Her2 negative breast cancer that has spread to other places in the body. Using markers to prompt when scans should be ordered may be as good as the usual …

A Master Protocol for a Randomized, Controlled, Clinical Trial of Multiple Pharmacologic Agents in Adult Participants with Metabolic Dysfunction-Associated Steatotic Liver Disease Who Are at Increased Risk of Developing Major Adverse Liver Outcomes (Synergy-Outcomes)

R
Raj Vuppalanchi, MD
18 years - 100 years
All genders
Interventional
This multicenter, randomized, parallel-arm, double-blind, placebo-controlled Phase 3 umbrella- type master protocol aims to create a framework for simultaneously evaluating the safety and efficacy of multiple pharmacologic agents (interventions) for the treatment of high-risk metabolic dysfunction-associated steatotic liver disease.THIS STUDY IS ENROLLING BY INVITATION ONLY - The study team will …

Real-World Effectiveness of Mepolizumab In Treating Chronic Obstructive Pulmonary Disease: A Multi-Country Prospective Study

R
Rajeev Mehta
40 years - 100 years
All genders
Observational
Evaluate the change in annualized rate of moderate/severe exacerbations in the 12-month period post-mepolizumab initiation compared to the 12-month pre-exposure periodTHIS STUDY IS ENROLLING BY INVITATION ONLY - The study will be identifying and enrolling adult patients ≥40 years of age with newly prescribed mepolizumab as add-on therapy per country-specific …

Handheld Point Of Care Electro-Diagnostic Device

S
Sergiu Abramovici
18 years - 100 years
All genders
Observational
We are developing a point of care, hand-held device, to be used by healthcare providers and assist them with clinical decision making and facilitate as well as expedite patient care, thus improving quality of care. The device we are studying is non-invasive, and we think it will improve quality of …

A Phase 3, Multicenter, Prospective Open-Label Study to Evaluate the Diagnostic Performance of [18F]Fapi-74 Pet/Ct for the Detection of Metastatic Disease in Adults with Pancreatic Ductal Adenocarcinoma

C
Cindy Yuan
18 years or above
All genders
This is a multi-site, open-label, non-randomized, single dose study to assess the clinical utility of [¹⁸F]FAPI-74 PET/CT in the detection of metastatic disease in individuals with pathologically confirmed pancreatic ductal adenocarcinoma. THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with most oncology trials, patients are not actively “recruited,” but are …

Clinical Outcomes of Medications Post Anti-Tnf: Researching Effectiveness in Pediatric Ibd

S
Steven Steiner, MD
1 years - 18 years
All genders
Observational
Over the past 10 years, new medication options have been approved for patients with IBD who did not respond to anti-TNF treatments. However, data is still limited for how these new medications work.   This study may provide researchers with valuable information about the continued use of these medications. The …

North American Fetal Therapy Network Fetal Myelomeningocele Repair Registry

H
Hiba Mustafa, MD
18 years - 100 years
Female
The data in the registry will be used to generate retrospective evaluations, investigations, and research studies.Objectives: (primary and important secondary objectives)•    Collect and analyze data regarding maternal outcomes at maternal-fetal surgery and delivery, with the ability to track subsequent reproductive outcomes.•    Collect and analyze data regarding fetal/neonatal outcomes at maternal-fetal surgery, birth …

Investigating the Temporal Relationship: Chemotherapy-Induced Peripheral Neuropathy in Children and Adolescents with Cancer

J
Jenny Belsky, DO
2 years - 20 years
All genders
Cancer treatment can sometimes lead to the development of a condition called peripheral neuropathy. This is when your arms, hands, legs, and feet may tingle, like they are asleep, or cause pain. We want to look at characteristics that might predict who will develop this condition. Only eligible patients that …
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