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Found 742 results
A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
A Prospective Study to Evaluate the Use of the Minder Device to Aid in Developing a Treatment Plan After Inconclusive Prolonged Eeg in Patients With Epilepsy
J
Jason Schwalb
The purpose of this research is to address the challenges of diagnosing and long-term management of epilepsy in participants whose seizures are not well captured by standard electroencephalography (EEG) tests and who cannot use or are not able to use more standard monitoring techniques. This research will compare the Minder …
Kysa-6: A Phase 2/3, Open-Label, Randomized, Controlled, Multicenter Study of Kyv-101, an Autologous Fully Human Anti-Cd19 Chimeric Antigen Receptor T-Cell (Cd19 Car T) Therapy, Versus Ongoing Standard-Of-Care Immunosuppressive Therapy in Patients With Generalized Myasthenia Gravis
A
Alex Barboi
Myasthenia gravis (MG) is a chronic autoimmune disease that affects the neuromuscular junction and is characterized by muscle weakness. B cells play a role in MG, and the disease is characterized by the presence of autoantibodies such as anti-AChR and anti-MuSK antibodies. CD-19 target chimeric antigen receptor (CAR) T cells …
A Double-Blind, Randomized, Placebo-Controlled, Multicenter, Outpatient, Parallel-Group Study to Assess the Efficacy and Safety of Staccato Alprazolam in Study Participants 12 Years of Age and Older With Stereotypical Prolonged Seizures
M
Marlene Bultemeher
The purpose of the study is to assess the success of a single administration of Staccato alprazolam compared with placebo both in rapidly terminating a seizure episode within 90 seconds and with no recurrence of seizure(s) up to 2 hours after investigational medicinal product (IMP) administration.THIS STUDY IS ENROLLING BY …
An Open-Label, Multicenter, Outpatient Extension Study to Evaluate the Safety and Tolerability of Staccato Alprazolam in Study Participants 12 Years of Age and Older With Stereotypical Prolonged Seizures
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Marlene Bultemeher
The purpose of the study is to evaluate the long-term safety and tolerability of Staccato alprazolam.THIS STUDY IS ENROLLING BY INVITATION ONLY
A Phase 2A Multicenter, Randomized, Platform Study of Targeted Therapies for the Treatment of Adult Subjects with Moderate to Severe Crohn's Disease
M
Monika Fischer, MD
Crohn's disease (CD) is a long-lasting disease that causes severe inflammation (redness, swelling), in the digestive tract, most frequently affecting the bowels. It can cause many different symptoms including belly pain, diarrhea, tiredness, and weight loss. Treatments are available but do not work the same for all patients or may …
A Phase 3 Global, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Nucresiran in Patients with Transthyretin-Mediated Amyloidosis with Cardiomyopathy
N
Noel Dasgupta
This is a Phase 3, global, randomized, double-blind, placebo-controlled, multicenter study to evaluate the efficacy, safety, PK, and PD of nucresiran in adult patients with ATTR amyloidosis (hereditary or wt) with cardiomyopathy. The purpose of this study is to:Evaluate the efficacy of nucresiran compared to placebo on reducing all-cause mortality and …
Cleopattra: Effects of Nnc6019-0001 Versus Placebo on Cardiovascular Outcomes in Participants With Transthyretin Amyloid Cardiomyopathy (Attr-Cm)
N
Noel Dasgupta
This study will find out if a new medicine called NNC6019-0001 can help reduce the risk of heart-related death and illness in participants with a condition called transthyretin amyloid cardiomyopathy (ATTR-CM), which affects the heart. THIS STUDY IS ENROLLING BY INVITATION ONLY
A Randomized Controlled, Open-Label, Rater-Blinded Pragmatic Trial, Treatment of Inflammatory Myelitis and Optic Neuritis With Early Vs Rescue Plasma Exchange (Timely-Plex)
D
Devon Mackay
The purpose of this research is to evaluate if early vs rescue Therapeutic Plasma Exchange (PLEX) treatment algorithm leads to better visual outcomes in severe Optic Neuritis and leads to better neurological disability outcomes in severe Transverse Myelitis.THIS STUDY IS ENROLLING BY INVITATION ONLY
A Phase 2, Randomized, Multicenter, Open-Label, Blinded-Endpoint Study to Evaluate the Safety of Regn7508 and Regn9933, Monoclonal Antibodies Against Fxi, Versus Apixaban in Participants With Atrial Fibrillation (Roxi-Atlas)
T
Tanyanan Tanawuttiwat
This study is researching experimental drugs called REGN7508 and REGN9933. The study is focused on participants who have atrial fibrillation, which means that the heart beats too fast and unevenly. REGN7508 and REGN9933 are designed to help stop blood clots forming in patients with atrial fibrillation.THIS STUDY IS ENROLLING BY …
A Prospective, Multicenter, Single Arm, Real-World Registry Assessing the Clinical Use of the Rotarex(Tm) Rotational Excisional Atherectomy System (Xtract Registry)
G
Gianvito Salerno
The XTRACT Registry is a prospective, single arm multicenter study on the use of on the Rotarex(TM) Rotational Excisional Atherectomy System.THIS STUDY IS ENROLLING BY INVITATION ONLY
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