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Found 716 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Filgotinib in Long-Term Extension Study of Adults With Crohn's Disease (DIVERSITYLTE)

M
Matthew Bohm, DO
18 years and older
All genders
Phase 3
Interventional
The primary objective of this study is to observe the long-term safety of filgotinib indults who have completed or met protocol specified efficacy discontinuation criteria in agotinib treatment study in Crohn's disease (CD).
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Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG (PACES)

J
Joel Corvera, MD
18 years and older
All genders
Phase 3
Interventional
The primary objective of this study is to evaluate the effectiveness (prevention ofhromboembolic events) and safety (major bleeding) of adding oral anticoagulation (OAC) to background antiplatelet therapy in patients who develop new-onset post-operative atrialbrillation (POAF) after isolated coronary artery bypass graft (CABG) surgery. All patients with a qualifying POAF event, …
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CARDIO-TTRansform: A Study to Evaluate the Efficacy and Safety of Eplontersen (Formerly Known as ION-682884, IONIS-TTR-LRx and AKCEA-TTR-LRx) in Participants With Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR CM)

N
Noel Dasgupta
18-90 years
All genders
Phase 3
Interventional
To evaluate the efficacy of eplontersen compared to placebo in participants with ATTR-CMving available standard of care (SoC). For more information, please visit https://www.cardio-ttransform.com.
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A Long-term Extension Study of Mirikizumab (LY3074828) in Participants With Crohn's Disease (VIVID-2)

M
Monika Fischer, MD
18 years and older
All genders
Phase 3
Interventional
The reason for this study is to determine the long-term efficacy and safety of the study drugkizumab in participants with Crohn's disease.
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Decreasing Delirium Through Music in Critically Ill Older Adults (DDM)

B
Babar Khan, MD
50 years and older
All genders
Interventional
Critically ill older adults admitted to the intensive care unit (ICU) are at a higher risk to develop delirium, which predisposes them to longer lengths of ICU and hospital stay,d in-patient mortality, and higher risk of new acquired cognitive impairment and dementia. Music listening is a non-pharmacological intervention that holds …
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Longitudinal Study of Mitochondrial Hepatopathies (MITOHEP)

J
Jean Molleston, MD
18 years and younger
All genders
Observational
The specific aims of this study are (1) to determine the clinical phenotypes and natural history of hepatic RC and FAO disorders, (2) to determine the correlation between genotyped phenotype, (3) to determine if circulating biomarkers reflect diagnosis and predict liver disease progression and survival with the native liver, (4) …
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Longitudinal Study of Genetic Causes of Intrahepatic Cholestasis (LOGIC) (LOGIC)

J
Jean Molleston, MD
25 years and younger
All genders
Observational
Cholestasis is a condition in which bile is not properly transported from the liver to the. Cholestasis can be caused by an array of childhood diseases, including the genetic diseases Alagille syndrome (ALGS), alpha-1 antitrypsin (a-1AT) deficiency, bile acidynthesis and metabolism defects, and progressive familial intrahepatic cholestasis (PFIC) or benign …
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iKanEat: A Randomized-controlled, Multi-center Trial of Megestrol for Chronic Oral Food Refusal in Children (iKanEat)

R
Ryan T. Pitman, MS, MD
9-108 years
Accepts healthy volunteer
All genders
Phase 4
This is a multi-center, randomized, placebo-controlled, double-blind clinical trial. They focus of the study is the evaluation of the effectiveness of treatment with megestrol24 week behavioral feeding protocol in transitioning from tube to oral feedingsdiatric population. Approximately 60 pediatric subjects matching the criteria forgibility will be enrolled in the study …
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Linking Endotypes and Outcomes in Pediatric Acute Respiratory Distress Syndrome (LEOPARDS)

C
Courtney Rowan, MD
44-17 years
All genders
Observational
The overall goal of the study is to risk stratify pediatric Acute Respiratory Distressyndrome (ARDS) patients and to identify sub-phenotypes with shared biology in order toy target therapies in future trials. This is a prospective, multicenter study of 500 intubated children with ARDS, with planned blood collection within 24 hours …
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Vitamin C Supplementation to Pregnant Smokers: Follow-up of 2 Randomized Trials Plus Changes in DNA Methylation (VCSIP-ECHO)

R
Robert Tepper, MD
6-11 years
All genders
Observational
In a randomized clinical trial (RCT) published in JAMA, the investigators have providedvidence that vitamin C supplementation (500 mg daily during pregnancy) ameliorates theking during pregnancy on offspring lung function and subsequentdence of wheeze by 48% through 1 year of age. The investigators are currently completingd RCT of vitamin C …
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