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Found 742 results

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Medical Management With Endovascular Thrombectomy Versus Medical Management Alone in Patients Presenting Beyond 24 Hours of Last Known Well - Select Late Trial

K
Kaustubh Limaye, MD
18 years - 85 years
All genders
Interventional
SELECT LATE trial aims to evaluate if addition of endovascular thrombectomy to medical management in patients presenting with acute ischemic stroke and a proximal large vessel occlusion in the anterior circulation between 24 and 72 hours of stroke onset results in achieving better functional outcomes (measured using modified Rankin Scale …

Evaluation Of Endothelial Cell And Other Lung Cell Populations In Lung Explants From Pvd Patients

D
David Roe, MD
18 years - 60 years
Accepts healthy volunteer
All genders
For patients with pulmonary vascular disease (PVD) in its end stage, lung transplantation becomes the only viable treatment option. Our study proposes to utilize lung explants from transplant recipients, organs deemed unsuitable/rejected for transplantation, and donors to evaluate cellular populations and molecular mechanisms in both diseased and healthy conditions, offering …

Optimization of Saturation Targets And Resuscitation (Optistart): Multicenter Randomized Controlled Trial

I
Izlin Lien, MD
10 minutes or below
All genders
Interventional
Purpose: Oxygen is the most commonly used drug during preterm resuscitation, but its use has been linked to mortality and several morbidities such as bronchopulmonary dysplasia (BPD), intraventricular hemorrhage (IVH), and retinopathy of prematurity (ROP).Preterm infants at birth are more vulnerable to oxygen toxicity caused by exposure to high concentrations …

Beta Testing Protocol for the Meridian M10 Mrsa/Sa Assay

T
Thomas E. Davis
18 years or above
All genders
Observational
This is a non-interventional method comparison study using prospectively collected nasal swab specimens collected from subjects via the informed consent process. The study is designed to assist MBI in determining the reference method to be used in Meridian M10 MRSA/SA assay clinical study.  The objective of this Beta Testing Protocol …

Appraisal of Spiritual Well-Being in Pediatric Inflammatory Bowel Disease

M
Marian Pfefferkorn
11 years - 18 years
All genders
Observational
Inflammatory Bowel Disease or IBD, causes parts of the intestine or bowel to get red and swollen. It’s a chronic condition, which means it lasts a long time or constantly comes and goes. Many children with IBD also have anxiety and depression. this study is looking to see how spirituality …

Low-Dose Radiation Therapy for Osteoarthritis: A Prospective Phase II Trial to Assess Pain Response

A
Arpan Prabhu
40 years or above
All genders
Phase 2
Observational
Low dose radiation in the treatment of benign diseases, including musculoskeletal disorders such as arthritis, is a standard clinical practice commonly utilized in some practices in the United States and even more commonly utilized in countries in Europe. This study will evaluate patients' pain and quality of life responses to …

Implementation of the Family-Centered Adolescent Sperm Banking Decision Tool (Fast)

A
Amanda J. Saraf, DO
13 years - 21 years
Male
The purpose of this study is to learn more about thoughts and experiences completing the FAST, a tool healthcare providers us as part of a fertility consult. This information may help us better incorporate the FAST into fertility consults at other healthcare institutions. THIS STUDY IS ENROLLING BY INVITATION ONLY - …

An Observational Study of Vykattm Xr (Diazoxide Choline Extended-Release Tablets) in Patients with Prader-Willi Syndrome (Pws)

M
Melissa Lah, MD
17 years or below
All genders
Observational
This is a prospective observational study developed to generate more evidence of the safety profile, clinical characteristics and outcomes of patients with Prader Willi syndrome treated with VYKAT XR. The study will take place in the US. It is anticipated that approximately 200 patients will be enrolled and followed for …

Duchenne Cardiomyopathy Mitigation Sglt2 Inhibitor (Cherish) Pharmacokinetic Study

L
Larry Markham
8 years - 18 years
All genders
Interventional
This is a pharmacokinetic study (PK Study) to better understand empagliflozin dosing in pediatric Duchenne muscular dystrophy patients. Empagliflozin is currently used off-label in this population due to the mortality benefits seen in adult cardiomyopathy and heart failure. We will perform PK studies in DMD patients of various ages and …

Concordance and Discordance in the Assessment of Volume Status in Home Dialysis Patients: A Comparison of Modified Medical Research Council Dyspnea Scale, Physical Exam, and Pocus

N
Nupur Gupta
18 years - 100 years
All genders
Observational
This study will compare fluid status evaluation by different modalities which include patient score (using a scale called modified medical research council dyspnea scale), physical examination by kidney doctor and Lung Ultrasound in order to learn the best way to judge how much fluid patients on home dialysis (including peritoneal …
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