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Found 742 results
A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Riley Hospital for Children Intensive Care Biorepository for Children with Acute Kidney Injury
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Michelle C. Starr, MD
The purpose of this project is to create a prospective database of children admitted to the neonatal, cardiovascular or pediatric intensive care units (NICU, CVICU and PICU) who have experienced an acute kidney injury (AKI). The goal of the database is to allow detailed clinical phenotypic and tracking of patient …
Unraveling the Immunological Triggers of Acute Cellular Rejection in Pediatric Liver Transplantation.
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Abby Russi
The proposed project is designed to prospectively collect blood and tissue from patients who have received a liver transplant (for any reason) to capture the immunoceullar landscape in the periphery preceding and target tissue during acute cellular rejection. It is a longitudinal collection of clinical data without study interventions.THIS STUDY …
Sc2I-Woundx-001-Woundx Pilot Trial: Proof of Concept Feasibility for the Clinical Operations of Woundx in Aiding Clinicians Identify Wounds That Are Ready For Surgical Closure
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Luke A. Lopas, MD
The purpose of this research is to evaluate the overall use of the WounDx medical device in a clinical setting, such as a hospital. The WounDx device is experimental and not yet approved by the United States Food and Drug Administration (FDA). WounDx uses information about a patient's wound to …
A Phase 1B, Open-Label, Multicenter, Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics Study of Ag-181 in Subjects With Phenylketonuria
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Melissa Lah, MD
This study is designed to evaluate the safety and efficacy of AG-181 in adults with phenylketonuria (PKU). People with the genetic condition phenylketonuria (PKU) have elevated levels of the amino acid phenylalanine (phe). Elevated levels of phe can lead to learning impairment, neuropsychological problems, ADHD, and other health problems. This …
Comparing the Efficacy of Systane Pro to Miebo for the Treatment of Dry Eye Disease
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ANNA TICHENOR
The goal of this study is to determine if SYSTANE® PRO is non-inferior to PFHO with regards to treating DED symptoms. TTHIS STUDY IS ENROLLING BY INVITATION ONLY - Adults ≥18 years of age who have corrected visual acuity of 20/100 or better and who have mild to moderate DED …
A Phase 2, Multicenter, Randomized, Placebo-Controlled, Double-Blind Study of the Efficacy and Safety of Vamifeport in Adult Subjects with Hfe-Related Hereditary Hemochromatosis
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Eric Orman
This is a phase 2, multicenter, randomized, placebo-controlled, double-blind, parallel-group, proof-of-concept study to assess vamifeport in adult participants with homeostatic iron regulator gene-related hereditary hemochromatosis (HFE-HH). The primary objective of the study is to assess the effect of vamifeport treatment on magnetic resonance imaging (MRI)-based liver iron concentration (LIC) in …
A Prospective Long-Term Follow-Up Study to Evaluate the Use of the Minder Device to Aid in Treatment After Actionable Event Identification in Patients Diagnosed With Epilepsy.
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Jason Schwalb
The purpose of this research is to address the challenges of correctly monitoring, managing, and diagnosing epilepsy in participants whose seizures are not well captured by standard electroencephalography (EEG) tests and who cannot use or are not able to use more standard monitoring techniques. This research is being done to …
Patient-Reported Outcomes to Understand Infant to Early Childhood Transition for Infants with Bronchopulmonary Dysplasia (Bpd)
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Rebecca Rose, MD
For preterm infants with bronchopulmonary dysplasia (BPD), the transition home from the neonatal intensive care unit (NICU) profoundly impacts both children and their parents. The goal of this study is to establish patient-reported measures that refine neonatal illness risk-stratification and identify barriers to post-discharge specialty care, in order to implement …
A Prospective, Single-Arm, Trial to Determine Contamination Rates when Using an Antibacterial Incise Drape During Orthopedic Surgery
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Leonard Buller
The goal of this clinical study is to generate data on the intended use of a chlorhexidine gluconate (CHG)-impregnated antimicrobial incise drape. The study includes subjects undergoing primary hip or knee arthroplasty procedures.THIS STUDY IS ENROLLING BY INVITATION ONLY - The Principal Investigator (Dr. Buller) and / or Dr. Sonn …
A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study to Investigate the Efficacy, Safety, and Pk/ Pd of Finerenone, in Addition to Standard-Of-Care, in Pediatric Patients, 6 Months to <18 Years of Age With Heart Failure (Hf) and Left Ventricular Systolic Dysfunction (Lvsd)
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R. Mark Payne, MD
Researchers are looking for a better way to treat children who have heart failure with left ventricular systolic dysfunction (LVSD). Heart failure is a serious condition where the heart is unable to pump enough blood to meet the body's needs. This can lead to symptoms like shortness of breath, fatigue, …
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