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Found 742 results

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

A Phase 3B/4, Multicenter, Parallel-Group, Double-Blind, Placebo Controlled, Two-Arm, Long-Term Study to Evaluate the Safety and Efficacy of Saroglitazar Magnesium on Clinical Outcomes in Participants With Primary Biliary Cholangitis (Pbc)

R
Raj Vuppalanchi, MD
18 years - 100 years
All genders
Phase 3
Interventional
The purpose of this study is to evaluate the effect of saroglitazar magnesium compared to placebo, based on time to the first occurrence of the defined clinical outcome events in participants with PBC.THIS STUDY IS ENROLLING BY INVITATION ONLY 

A Randomized, Double-Blind, Placebo-Controlled, Multicenter Trial of Resmetirom for the Treatment of Metabolic Dysfunction- Associated Steatotic Liver Disease (Masld) in People Living With Human Immunodeficiency Virus (Hiv)

S
Samer Gawrieh, MD
18 years - 100 years
All genders
Interventional
The purpose of this research study is to test the safety and effectiveness of the study drug, resmetirom, in participants with MASLD and HIV. This is a research study to test a drug that is already on the market with a population that was not included in the original clinical …

Assessment of Skeletal Maturity Biomarkers in the Gingival Crevicular Fluid of Orthodontic Patients

R
Rishma Shah
7 years - 20 years
Accepts healthy volunteer
All genders
The purpose of this study is to find a non-invasive technique of measuring growth hormone-related factors to provide a prediction of future growth of a patient. The study will investigate factors in the fluid residing between the teeth and gums, and correlate this with age, height, weight, and indicators on …

A Phase 2/3, Randomized, Double-Blind, Multicenter, Placebo-Controlled Study Of Inebilizumab In Participants With Autoimmune Hepatitis

C
Craig Lammert, MD
18 years - 74 years
All genders
Phase 2/3
Interventional
This is a randomized, multicenter, double-blind, phase 2/3 study to evaluate the efficacy and safety of inebilizumab in participants with active AIH who are inadequatelyresponding and/or are intolerant to SOC. The main objectives of this trial are to evaluate the safety and tolerability of inebilizumab in participants with autoimmune hepatitis …

Genetic Determinants of Persistent Lactic Acidosis in Major Burn Patients: A Whole-Genome Sequencing Approach

F
Faith Zor
18 years - 100 years
All genders
Observational
The purpose of this study is to find out whether certain genetic differences may explain why some severely burned patients continue to have high lactic acid levels in their blood even after receiving proper medical treatment. We will collect a small blood sample from each patient and analyze their DNA …

Weatherization For At Risk Asthma Patients (Wrap)

N
Nadia Krupp, MD
100 years or below
All genders
Observational
This study will investigate the health effects of a community environmental remediation program on asthma control and outcomes. The long-term goal of this study is to inform future prospective studies exploring environmental interventions in children and adolescents with poorly controlled severe asthma.Objectives:Recruit and complete weatherization services for at least 20 …

Rezpegaldesleukin (Nktr-358) in New Onset Type 1 Diabetes Mellitus

L
Linda DiMeglio, MD
8 years - 45 years
All genders
Phase 2
Interventional
This Phase 2 study is a 2-arm, multi-center, double-masked, placebo-controlled, 2:1 randomized sequential trial design in new onset T1D participants (within 100 days of diagnosis). THIS STUDY IS ENROLLING BY INVITATION ONLY 

A Phase 3, Randomized, Double-Blind, 48-Week Placebo-Controlled Study to Assess the Efficacy, Safety, and Tolerability of Dyne-101 Administered to Participants with Myotonic Dystrophy Type 1

L
Laurie Gutmann
16 years or above
All genders
Phase 3
Interventional
This Phase 3 study was designed based on the results of ACHIEVE. It is a randomized,double-blind study with a 48-week Placebo-Controlled Period to assess the efficacy, safety,and tolerability of DYNE-101 administered IV to participants with DM1 aged ≥16 years.This study is adequately powered to evaluate the effect of DYNE-101 50 …

A Phase 3, Randomized, Double-Blind Study to Evaluate the Efficacy and Safety of Veverimer in Adults with Ckd and Metabolic Acidosis (REVIVE)

K
Kenneth Lim
18 years - 100 years
All genders
Phase 3
Interventional
The purpose of this 26 week study is is to evaluate the efficacy and safety of veverimer in treating adults with moderate-to-severe chronic kidney disease (CKD) and metabolic acidosis.THIS STUDY IS ENROLLING BY INVITATION ONLY

Cannulated Bone Bolt® Screw System Versus Standard Cannulated Screw System Fixation for Lateral Compression Type-1 (Lc-1) Pelvic Ring Injuries: Multicenter Prospective Observational Study

D
Dillon O'Neill
18 years - 80 years
All genders
Observational
The purpose of this study is to evaluate recovery and outcomes following cannulated Bone Bolt® screw system versus standard cannulated screw system fixation for LC-1 pelvic ring injuries. The devices being studied are not investigational and have been approved for use by the FDA. The study team is evaluating recovery …
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