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Found 742 results
A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
A Randomized, Placebo-Controlled, Double-Blind Phase 3 Study to Evaluate the Efficacy, Safety and Tolerability of Votoplam in Participants With Huntington's Disease
C
Christopher James
The purpose is to assess safety and tolerability of votoplam and to determine whether votoplam slows disease progression in patients with early symptomatic Huntington's disease (HD) compared to the control arm.THIS STUDY IS ENROLLING BY INVITATION ONLY
Defining the Effect of Gastric Electrical Stimulation on Serum Insulin Levels in Human Subjects
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Thomas Nowak, MD
The purpose of this study is to determine if hormone levels (Insulin, Glucose, C-peptide, and GLP-1) are significantly affected by turning off the Gastroelectric Stimulator device, for up to 4 hours, in individuals that have gastroparesis with a Stimulator implanted, and are not on any insulins. Researchers would also like …
Early Detection of Neonatal Opioid Withdrawal Syndrome Using a Novel Cerebral Monitor
A
Anna Elizabeth Thomas
This study is being conducted to investigate whether blood flow and/or oxygenation in the brain of babies exposed to opioids during pregnancy can predict the severity of neonatal opioid withdrawal symptoms (NOWS). This study will use a novel, safe, non-invasive brain monitoring device to measure blood flow and oxygen levels …
A Phase 3 Randomized, Double-Blind, Placebo-Controlled, Parallel Group, Multicenter Protocol in Adults With an Open Label Study in Adolescents to Evaluate the Efficacy and Safety of Induction and Maintenance Therapy With Icotrokinra in Participants With Moderately to Severely Active Ulcerative Colitis
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Monika Fischer, MD
The purpose of this protocol is to evaluate the efficacy (how well it works), safety and tolerability of oral icotrokinra as therapy in adult and adolescent participants with moderately to severely active ulcerative colitis (UC, a chronic disease of the large intestine in which the lining of the colon becomes …
Fixation Versus Arthroplasty Surgical Treatments for Early Recovery After Hip Fracture (Faster-Hip)
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Dillon O'Neill
The goal of this study is to determine if arthroplasty is superior to internal fixation when used to treat minimally displaced femoral neck fractures.THIS STUDY IS ENROLLING BY INVITATION ONLY - All patients presenting to a participating clinical site will be prospectively screened for eligibility in each active intervention domain …
Hpc Offered for Preserve Expansion
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Jodi Skiles
Ossium produces cryopreserved hematopoietic progenitor cell bone marrow (HPC, Marrow (Cryopreserved)) recovered from deceased organ donors using good manufacturing practice (GMP) processing, Ossium’s HPC, Marrow (Cryopreserved) is supplied in units suitable for transplantation by infusion, the same procedure used for transplantation of other sources of HPCs, such as live donor …
Phase 1 Imaging Study of 68Ga-R12961 in Advanced Solid Tumors
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Cindy Yuan
The goals of this study are:To describe the safety of 68Ga-R12961To describe preliminary imaging efficacy of 68Ga-R12961 in participants with advanced solid tumors.To compare 68Ga-R12961 positron emission tomography/computed tomography (PET/CT) scans with standard of care imaging in detecting tumor lesions among participants.To describe the image quality of 68Ga-R12961.To determine organ …
Adaptive Optics Gonioscopy In Vivo Imaging of the Effects of Rhopressa on the Trabecular Meshwork in Patients with Ocular Hypertension or Glaucoma
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Brett Joseph King
This is a prospective, randomized, single-masked study investigating the mechanism of action of Rhopressa (netarsudil) topical ophthalmic medication compared to a placebo drop (artificial tear). THIS STUDY IS ENROLLING BY INVITATION ONLY - Potential participants with a diagnosis of ocular hypertension or open-angle glaucoma (excluding pigment dispersion) will be identified by …
A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study with a Separate Open-Label Cohort to Evaluate the Efficacy and Safety of Brenipatide as Adjunctive Treatment to Transmucosal Buprenorphine with or Without Naloxone in Early Recovery of Participants with Opioid Use Disorder (Renew-Op-1)
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Michael A. Bushey
Study GZMG is a multicenter, Phase 2 study designed to evaluate the efficacy and safety of brenipatide as an adjunctive treatment to BUP±NX, in participants with OUD who are in early recovery. The purpose of this study is to assess the efficacy and safety of brenipatide at different dose levels …
A Phase 3, Randomized, Double-Blind, Placebo-Controlled, 3-Arm Study to Investigate the Safety and Efficacy of Efimosfermin Alfa in Participants With Biopsy-Confirmed F2- or F3-Stage Metabolic Dysfunction-Associated Steatohepatitis (Mash) (Zenith-1)
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Raj Vuppalanchi, MD
The purpose of this study is to assess the safety and efficacy of efimosfermin alfa in the resolution of steatohepatitis and improvement of liver-related clinical outcome compared to placebo in individuals with MASH and biopsy-confirmed F2- or F3-stage fibrosis.THIS STUDY IS ENROLLING BY INVITATION ONLY
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