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Found 715 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Crohn's Disease: Pharmacokinetics, Efficacy, and Safety of Risankizumab in Pediatric Subjects with Moderately to Severely Active Crohn's Disease

T
Tina Zhang
2-18 years
All genders
Interventional
What is this study about?The objective of this study is to assess the pharmacokinetics (PK), efficacy, and safety of risankizumab in pediatric subjects with moderately to severely active CD aged 2 to < 18 years old who have had intolerance or inadequate response to aminosalicylates, oral locally acting corticosteroids, systemic …
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A study to test whether spesolimab helps people with a skin disease called hidradenitis suppurativa (Lunsayil 1)

D
David Rosmarin
18-75 years
All genders
Phase 2/3
Interventional
What is this study about?Hidradenitis suppurativa (HS) is a painful skin condition with recurring lumps, abscesses, and tunnels that drain unpleasant fluids, significantly affecting quality of life. Spesolimab is a new treatment being studied for its potential to reduce these symptoms by blocking certain immune responses. This study aims to …
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A Study of Milvexian Versus Apixaban in Participants With Atrial Fibrillation (LIBREXIA-AF)

J
John Strobel, MD
18 years and older
All genders
Phase 3
Interventional
The purpose of this study is to evaluate if milvexian is at least as effective as apixabanducing the risk of the composite stroke and non- central nervous system (CNS) systemicbolism.
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Exercise in Metastatic Breast Cancer: EMBody

T
Tarah Ballinger, MD
18 years and older
All genders
Phase 2
Interventional
What is the purpose of this study?The purpose of this study is to study exercise in a novel population with indolent MBC (nogression on current therapy in prior 12 months and not receiving cytotoxic chemotherapy). The study team hypothesizes that delivering virtual, supervised, progressive intensitybic and resistance training exercise for …
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Pilot RCT of Self-stigma Treatment for First Episode Psychosis (NECT-YA)

B
Bethany Leonhardt
15-24 years
All genders
Interventional
What is the purpose of this study?The purpose of this study is to conduct preliminary testing of a group psychotherapy invention (Narrative Enhancement and Cognitive Therapy; NECT). This intervention targets self-stigma and illness conceptions among persons with first-epiosde psychosis with the goal of increasing treatment engagement. THIS STUDY IS ENROLLING …
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Mismatched Related Donor Versus Matched Unrelated Donor Stem Cell Transplantation for Children, Adolescents, and Young Adults With Acute Leukemia or Myelodysplastic Syndrome

T
Toshihiro Onishi, MD
6-21 years
All genders
Phase 3
Interventional
What is the purpose of this study?This phase III trial compares hematopoietic (stem) cell transplantation (HCT) usinghed related donors (haploidentical [haplo]) versus matched unrelated donors (MUD) ing children, adolescents, and young adults with acute leukemia or myelodysplasticyndrome (MDS). HCT is considered standard of care treatment for patients with high-riskute leukemia …
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Niraparib in Combination With Dostarlimab in Patients With Recurrent or Progressive Cervix Cancer (STAR)

S
Sharon E. Robertson
18 years and older
Female
Phase 2
Interventional
What is the purpose of this study?The purpose of this research study is to test the safety of Niraparib and dostarlimab as abination treatment and see what effects (good and bad) this combination treatment has onwith recurrent or progressive cervix cancer.THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with …
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ONC201 in H3 K27M-mutant Diffuse Glioma Following Radiotherapy (the ACTION Study) (ACTION)

M
Michael Ferguson, MD
All genders
Phase 3
Interventional
What is the purpose of this study?This is a randomized, double-blind, placebo-controlled, parallel-group, international, Phase 3 study in patients with newly diagnosed H3 K27M-mutant diffuse glioma to assess whether treatment with ONC201 following frontline radiotherapy will extend overall survival and progression-free survival in this population. Eligible participants will have histologically …
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Non-Invasive Quantification of Liver Health in NASH (N-QUAN)

R
Raj Vuppalanchi, MD
18-75 years
All genders
Interventional
To evaluate, in patients with suspected NASH referred for liver biopsy, the diagnosticCT1 at discriminating those with NAS≥4 & F≥2 from those without.
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A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study to Evaluate the Efficacy, Safety, and Tolerability of Upadacitinib in Adult and Adolescent Subjects With Non-Segmental Vitiligo Who Are Eligible for Systemic Therapy

D
David Rosmarin
12-75 years
All genders
Phase 3
Interventional
What is the purpose of this study?Vitiligo is a common chronic autoimmune disease that causes the body's immune system to attack its own pigment producing skin cells. This study is to evaluate how safe and effective upadacitinib is in participants with non-segmental vitiligo (NSV). Adverse effects and change in disease …
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