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Found 742 results

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Novel Use of Combined High-Speed Video Microscopy and Nasal Nitric Oxide Screening for Identification of Primary Ciliary Dyskinesia in Adult Bronchiectasis

M
Mike Davis
18 years or above
All genders
Observational
Bronchiectasis is a chronic respiratory disease characterized by irreversible airway damage and recurrent infection, and many patients remain without an identifiable cause even after standard testing. Primary ciliary dyskinesia (PCD), a genetic disorder that causes bronchiectasis due to defecttive mucus clearance in the lungs, is substantially underdiagnosed in adult bronchiectasis …

Evaluation of Body Composition Among Infants with Ckd and Esrd: A Prospective Pilot Study

M
Michelle C. Starr, MD
12 months or below
All genders
Observational
The objectives of this study are to generate evidence that improves the assessment of nutritional status in infants with CKD and ESKD, to differentiate malnutrition from fluid imbalance, and to inform individualized nutritional and medical interventions aimed at optimizing growth and developmental outcomes.THIS STUDY IS ENROLLING BY INVITATION ONLY - …

Promise Registry: Prospective Study on Management of Ischemic Stroke Secondary to Mevo Registry

K
Kaustubh Limaye, MD
18 years - 85 years
All genders
Observational
The primary objective of this study is to better understand the change in landscape, post clinical trials publication, of the management of medium vessel occlusion (MevO) causing acute ischemic strokes (AIS) in the first 24 hours. This study will help us better understand the “equipoise” in the eyes of practicing …

Natriuretic Peptides for Low Volume Platforms Enrollment Study Protocol

N
Nicholas Harrison
22 years - 100 years
All genders
Observational
The purpose of this study protocol is to collect blood samples and relevant medical data from the intended use population presenting with a clinical suspicion of acute heart failure (i.e. new-onset heart failure or worsening symptoms suggestive of decompensated or exacerbated heart failure).  Blood samples are collected to support assay …

Efficacy and Safety of Nnc0487-0111 Compared to Placebo on Morbidity and Mortality in People with Heart Failure with Preserved or Mildly Reduced Ejection Fraction and Obesity (Hf-Polaris).

O
Onyedika Ilonze
18 years - 100 years
All genders
Interventional
This study is being done to look at the safety and effect of NNC0487-0111 in people with Heart Failure with preserved Ejection Fraction (HFpEF) or Heart Failure with mildly reduced Ejection Fraction (HFmrEF) and excess body weight when compared to placebo. The purpose of this clinical study is to find …

The Effect of Transcutaneous Vagal Nerve Stimulation on the Inflammatory Response to Spine Surgery

C
Cristina Barboi
18 years - 100 years
All genders
Interventional
The purpose of the study is to determine the feasibility postoperative vagal nerve stimulation and measure the effect on the plasma inflammatory markers on postoperative days 1-3.THIS STUDY IS ENROLLING BY INVITATION ONLY - Recruitment and eligibility screening will occur through standard clinical pathways within the Department of Neurosurgery. Spine …

The Impact of Exercise on Skeletal Muscle Function in Lung Transplant Recipients

G
Gary Long
18 years - 100 years
All genders
Observational
Individuals post lung transplant suffer from significantly reduced exercise capacity. Physical rehabilitation (such as that carried out in COLTT) has previously been shown to improve aerobic endurance and muscle strength, both of which are associated with improved survival. Unfortunately, there is very little known about the mechanisms behind these improvements. …

Renal Functional Reserve as Long-Term Predictor of Kidney Disease Progression in Children

A
Andrew Schwaderer, MD
12 years - 17 years
All genders
Interventional
Normal kidney has the ability to increase its filtration rate in response to a stress such as a protein load. In chronic kidney disease, the existing kidney functional units(nephrons)may already be operating at their maximum operating capacity and may not have much reserve available to increase filtration in response to …

Fgf-21 as a Treatment-Response Biomarker of Anabolic Therapy in Adult Major Burn Injury

S
Sunnie Wong
18 years - 100 years
All genders
Observational
Anabolic therapies, including testosterone supplementation and somatropin, are routinely used in adult burn care to attenuate muscle wasting and support recovery. However, objective markers capable of assessing metabolic response to anabolic therapy during acute hospitalization remain limited. This study will assess whether standard-of-care anabolic therapy modifies biological markers of burn …

Fear of Cancer Occurrence: Development and Initial Psychometric Testing of a Fear Measure for Breast Cancer Previvors

S
Shelley Johns
18 years - 100 years
Female
To develop a measure of cancer-related fear in previvors, women with an increased risk of developing breast cancer within their lifetime but have never had a cancer diagnosis. Two existing fear measures will be used to develop the initial fear of cancer occurrence (FOCO) measure, then two rounds of cognitive …
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