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Found 742 results
A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Prospective Evaluation of Venous Congestion Using the Venous Excess Ultrasound Score (Vexus) During Early Fluid Resuscitation in Adult Patients With Major Burns
S
Sunnie Wong
This study aims to prospectively characterize venous congestion during early burn resuscitation by use of ultrasound and evaluate its relationship to traditional resuscitation metrics.THIS STUDY IS ENROLLING BY INVITATION ONLY - Potential subjects will be identified by the investigators by EMR review of burn ICU admissions. The investigators will meet …
A Phase 3, Multicenter, Prospective, Randomized, Open-Label Efficacy and Safety Study of Intravenous Brincidofovir Versus Intravenous Cidofovir for Treatment of Adenovirus Infection in Pediatric and Adult Subjects After Allogeneic Hematopoietic Cell Transplantation (Allo-Hct)
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Jodi Skiles
This randomized, open-label, parallel group, two-arm, multi-center assessment will compare IV BCV with IV CDV in adult and pediatric allogeneic HCT recipients with AdV viremia. A virologic response-driven approach to duration of treatment will be evaluated, in which randomized subjects are treated with either BCV or CDV until AdV viremia …
Prospective Sample Collection Of Subjects For The Development Of Multiple Immunosuppressant Therapeutic Drug Monitoring Assays
A
Asif Sharfuddin
The primary aim of this study is to collect biological samples that may be used in the development of future multi-drug immunosuppressant therapeutic drug monitoring assays in solid organ transplant recipients.THIS STUDY IS ENROLLING BY INVITATION ONLY - The Investigator will collect samples from up to 3,000 adult subjects who …
Comparing Approaches to Helping People with Chronic Traumatic Brain Injury Manage Their Health Care
F
Flora Hammond, MD
To better understand the efficacy of a person-centered approach to enhance health empowerment/self-efficacy and engagement among persons with chronic Traumatic Brain Injury (TBI).THIS STUDY IS ENROLLING BY INVITATION ONLY - Brain injury physician clinics across the US will refer potential participants. Brain injury physicians recruiting for this study are a …
Sample Collection for Research Studies Related to Pulmonary Disorders and Other Diseases of Interest in Infants (Infant Biobank)
S
Stephanie Adaikalam
The broad scientific objective of the Division of Pediatric Pulmonology, Allergy-Immunology and Sleep Medicine (PPUL) at Riley Hospital for Children is to promote translational research for the improved understanding and advancement in the treatment of health disorders. The ability to successfully investigate the biological basis of diseases, translate basic research …
A Test-Negative Case-Control Study to Evaluate the Effectiveness of V116, Capvaxive (Tm) Against Pneumococcal Pneumonia in Older Adults
S
Samir Gupta, MD
The purpose of this study is to assess the effectiveness of CAPVAXIVE in preventing hospitalized, confirmed CAP (invasive and non-invasive) caused by S pneumoniae serotypes contained in CAPVAXIVE and/or cross-reactive serotypes 6C and 15B among participants who received no other pneumococcal vaccines than CAPVAXIVE in the previous 5 years.THIS STUDY …
A Phase 3, Multicenter, Clinical Study To Evaluate The Efficacy And Safety Of Safusidenib Erbumine In Participants With Isocitrate Dehydrogenase 1 (Idh1)-Mutant Glioma
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Kathryn Nevel
This is a 3-part study. The purpose of Part 1 of the study is to evaluate the efficacy, safety, and pharmacokinetic (PK) characteristics of safusidenib in participants with recurrent/progressive IDH1-mutant World Health Organization (WHO) Grade 2 or Grade 3 glioma.The purpose of Part 2 will be to evaluate the efficacy …
Improving Measurement of Neonatal High Blood Pressure Using the Boppli Device
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Cara Slagle
The purpose of this study is to test how well a new soft, wearable blood pressure device (Boppli™) measures blood pressure in babies compared to the standard blood pressure cuff used in the NICU. We will also look at whether cuff measurements may temporarily raise a baby’s blood pressure. Information …
Comparison of Two Group Wellness Interventions for Individuals with Neurologic Conditions and Their Support Persons: A Randomized Clinical Trial
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Devan Parrott
The goal of this study is to examine efficacy of the treatment in individuals with chronic mild TBI and their caregivers and to determine whether patient neurobehavioral functioning moderates the relationship between treatment outcomes and burden in caregivers. Beyond injury-based cohorts, we sought to examine whether WeCAN would be efficacious …
Pure: Proteome Analysis of Urgo Clean Ag-Treated Regenerative Wound Exudate
M
Mithun Sinha
Single-site, prospective, observational/specimen-collection pilot embedded in standard-of-care venous leg ulcer (VLU) management. One target dressing will be collected after 7 days of wear for proteomic analysis. THIS STUDY IS ENROLLING BY INVITATION ONLY - This study is enrolling adults (≥18 years) with a chronic VLU receiving standard compression therapy and presenting …
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