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Found 742 results

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Collection of Pooled Uremic Serum for In Vitro Models

K
Kenneth Lim
18 years or above
All genders
Observational
The purpose of the study is to collect human serum from patients with uremia and healthy volunteers that will be used to create physiologically relevant cell culture models. These models will be used to study the impact of uremia on cardiovascular cells.THIS STUDY IS ENROLLING BY INVITATION ONLY - Recruitment …

A Phase 3, Open-Label, Multicenter, Single-Arm Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Efficacy of Dulaglutide 3.0 Mg and 4.5 Mg in Pediatric Participants 10 to Less Than 18 Years of Age With Type 2 Diabetes Mellitus

T
Tamara Hannon, MD
10 years - 17 years
All genders
Phase 3
Interventional
The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics, and efficacy of dulaglutide 3.0 mg and 4.5 mg in pediatric participants 10 to less than 18 years of age with T2DM.THIS STUDY IS ENROLLING BY INVITATION ONLY

Prevalence of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) in High-Risk Patients Presenting to Primary Care

R
Raj Vuppalanchi, MD
40 years or above
All genders
Observational
This study will provide the first comprehensive real-world prevalence data on MASLD in a primary care-based high-risk population, using validated non-invasive imaging. Results will inform evidence-based screening guidelines, support integration of FibroScan into PCP workflows, and facilitate early intervention to reduce progression to advanced liver disease. Identified predictors of significant …

Long-Term Outcomes of Skull Base Repair for Spontaneous CSF Leaks

R
Rick Nelson, MD
18 years - 100 years
All genders
Observational
This is a prospective observational study with the purpose of evaluating the durability of the bone cement repair used to treat spontaneous cerebrospinal fluid leaks (SCSFL). Long-term follow-up data will be collected from the EMR from standard of care procedures. Additionally, subjects will be asked to complete a one-time questionnaire …

Prospective Assessment of Health-Related Quality of Life and Caregiver Burden in Children and Parents of Children with Lower Urinary Tract Dysfunction with Validation of the Riley Bladder Quality of Life Questionnaire (RiBQQ)

N
Nikhil Batra
8 years - 17 years
All genders
Observational
This is a prospective study to assess both validated and non-validated questionnaires and quality of life tools in children with LUTD. Additionally, we will obtain data from parents/guardians of children with LUTD and parents/guardians of children without LUTD to assess health care burden of LUTD.THIS STUDY IS ENROLLING BY INVITATION …

A Pilot Clinical Study to Evaluate the Technical and Operational Performance of Lovelace in Comparison with the Clinical Standard-of-Care CardioTocoGraph (CTG) for Antepartum Fetal Monitoring.

D
David Haas, MD
18 years - 100 years
Female
Observational
The purpose of this study is to evaluate the technical and operational performance of Lovelace in comparison with the clinical standard-of-care CTG for antepartum fetal monitoring (i.e. NST), and to collect evidence of its safety. The main objective is to evaluate the safety and performance of Lovelace for antepartum monitoring …

A Study of Uveitis in Children <18 Years of Age

K
Kathryn Haider, MD
17 years or below
All genders
Observational
The goal of this observational study is to collect data regarding clinical features and current/past treatments in children under 18 with uveitis. The main questions it aims to answer are:What are the frequency of uveitis subtypes in children?What are clinical and demographic characteristics overall and within each type of uveitis?THIS …

Prospective Measurement of Normative Esophageal Distensibility Using EndoFLIP in Asymptomatic Children

B
Brett Hoskins
5 years - 17 years
All genders
Interventional
Endoluminal functional lumen imaging probe (EndoFLIP) is a minimally invasive, novel device that aids in the diagnosis of esophageal disorders. EndoFLIP is increasingly utilized for assessing esophageal biomechanics, yet normative data for children are lacking. Due to developmental differences in compliance and luminal size, adult reference values are not generalizable …

Peer Support Groups for Youth with Diabetes

T
Tamara Hannon, MD
15 years - 25 years
All genders
Observational
Youth with type 1 or type 2 diabetes mellitus (T1D; T2D) from low socioeconomic backgrounds in rural western Kenya and in urban or rural Indiana struggle with poor glycemic control and have limited access to peer-support and ongoing diabetes education. The impact of peer-support and education groups that address social, …

Evaluating Sensory Assessment Methods for Measuring Facial Cutaneous Sensation

G
Gregory Borschel, MD
8 years or above
All genders
Observational
The most common sensory assessment methods currently used in clinical practice include the Moving and Static Two-Point Discrimination Test (2PD), Semmes–Weinstein Monofilament Test (SWM), and the Ten Test (TT). Despite advancements in sensory assessment methods, the application of these tests has largely remained confined to the hand. To date, limited …
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