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Found 768 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Investigation of HER2-Targeted Therapy Duration for Early-Stage HER2+ Breast Cancer

K
Kathy Miller, MD
18 years - 100 years
All genders
Phase 3
This study investigates the effects of different durations of HER2-targeted therapy in patients with early-stage HER2-positive breast cancer. HER2-positive breast cancer is a type of cancer where a protein called HER2 is found on the surface of the cancer cells. This protein can make cancer cells grow faster. The purpose …
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Study of Treatments for Relapsed B-Cell Acute Lymphoblastic Leukemia

S
Sandeep Batra, MD
1 year - 30 years
All genders
Phase 2
Interventional
This study investigates the effects of two investigational medications, blinatumomab and nivolumab, in patients with B-cell acute lymphoblastic leukemia (B-ALL) that has relapsed. B-ALL is a type of cancer that affects the white blood cells. The study includes patients with Down syndrome and aims to compare the outcomes of using …
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Study of DNA Repair in Lung Disease Patients Exposed to Airborne Pollutants

C
Catherine Sears, MD
18 years or above
All genders
This study investigates how airway and blood cells from adult patients repair DNA after exposure to airborne pollutants, such as tobacco smoke. The purpose is to understand the effects of these pollutants on DNA repair mechanisms in different cell types. We will collect cells from the airways and blood of …
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Investigating Barriers to Emergency Department Survey Participation

D
Diane Kuhn
18 years - 39 years
All genders
Observational
This study investigates the barriers and facilitators to completing emergency department (ED) patient experience surveys among underrepresented groups. The purpose is to understand the perspectives of younger patients, Black or African-American patients, and those with Medicaid insurance on how they can provide feedback on their care.Participants will take part in …
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Studying Special Bandages for Hard-to-Heal Wounds

M
Mithun Sinha
18 years - 100 years
All genders
Interventional
This study investigates the effects of using a tri-layer amnion graft or a single-layer amnion graft for patients with hard-to-heal diabetic foot ulcers (DFUs) and venous leg ulcers (VLUs). These ulcers are wounds that are difficult to heal and may require special treatments. The study compares these treatments to a …
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Investigational Medication for ALS: Expanded Access Program

C
Cynthia Bodkin, MD
18 years - 100 years
All genders
This study investigates an Expanded Access Program for people with Amyotrophic Lateral Sclerosis (ALS). ALS is a disease that affects nerve cells in the brain and spinal cord, leading to loss of muscle control. The purpose of this program is to provide access to an investigational medication for ALS patients …
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Research Study on Investigational Medication for HER2 Expressing Tumors

J
Jonathan L. Berkowitz, MD, PhD
18 years - 120 years
All genders
Phase 2
Interventional
This study investigates an investigational medication for treating certain tumors that express a protein called HER2. HER2 is a protein that can affect the growth of some cancer cells. The study includes different types of cancers such as bladder, biliary tract, cervical, endometrial, ovarian, pancreatic, and some rare tumors.Participants will …
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S1703 Serum Tumor Marker Directed Disease Monitoring in Patients With Hormone Receptor Positive Her2 Negative Metastatic Breast Cancer

J
Jonathan L. Berkowitz, MD, PhD
18 years or above
All genders
Interventional
This randomized research trial studies how well serum tumor marker directed disease monitoring works in monitoring patients with hormone receptor positive Her2 negative breast cancer that has spread to other places in the body. Using markers to prompt when scans should be ordered may be as good as the usual …
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Investigating Treatments for Fatty Liver Disease Related to Metabolic Issues

R
Raj Vuppalanchi, MD
18 years - 100 years
All genders
Interventional
This study investigates metabolic dysfunction-associated steatotic liver disease (MASLD), a condition where fat builds up in the liver due to metabolic issues. The purpose of this study is to assess the safety and effectiveness of different investigational medications for adults with MASLD who are at high risk of serious liver …
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Investigating the Effects of an Investigational Medication in Treating Chronic Obstructive Pulmonary Disease

R
Rajeev Mehta
40 years - 100 years
All genders
Observational
This study investigates how an investigational medication works for people with Chronic Obstructive Pulmonary Disease (COPD). COPD is a lung disease that makes it hard to breathe and gets worse over time. This study looks at how often people with COPD have flare-ups, or worsening symptoms, after starting the investigational …
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