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Found 5 Amyloidosis trials

A listing of Amyloidosis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Sympathetic Nerve Activity in Amyloid Polyneuropathy

N
Noel Dasgupta
18 years - 90 years
Accepts healthy volunteer
All genders
The purpose of this study is use skin nerve activity to compare the response of the nervous system to stress within the nerves of the skin that may not be noticed in patients with transthyretin amyloidosis versus volunteers without amyloidosis.
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A Study to Assess the Long-Term Safety and Efficacy of Eplontersen (Formerly Known as ION-682884, IONIS-TTR-LRx and AKCEA-TTR-LRx) in Patients With Hereditary Transthyretin-Mediated Amyloid Polyneuropathy

N
Noel Dasgupta
18 years or above
All genders
Phase 3
Interventional
The purpose of this study is to evaluate the safety and tolerability of extended dosing withwith hereditary transthyretin-mediated amyloid polyneuropathy (hATTR-PN).
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Investigation of an Investigational Medication for Heart Disease Caused by Protein Build-up

N
Noel Dasgupta
18 years - 85 years
All genders
Phase 3
Interventional
This study investigates the effects of an investigational medication for patients with transthyretin-mediated amyloidosis (ATTR) with cardiomyopathy. ATTR amyloidosis is a condition where abnormal proteins build up in organs, including the heart, which can lead to heart problems. Cardiomyopathy refers to diseases of the heart muscle that make it harder …
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MAGNITUDE: A Phase 3, Multinational, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of NTLA-2001 in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM)

N
Noel Dasgupta
18 years - 100 years
All genders
Phase 3
Interventional
What is the purpose of this study?To evaluate the efficacy and safety of a single dose of NTLA-2001 compared to placebo in participants with ATTR-CM. 
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A Non-interventional, Prospective, Multi-country Study Collecting Real-world Data on the Characteristics, Treatment Patterns, and Outcomes of Patients With Transthyretin (ATTR) Amyloidosis

N
Noel Dasgupta
18 years or above
All genders
Observational
What is the purpose of this study?MaesTTRo is an international, longitudinal, non-interventional study of adult patients with transthyretin (ATTR) amyloidosis. The MaesTTRo study aims to enroll a global cohort of patients with transthyretin (ATTR) amyloidosis to longitudinally observe the natural course of the disease and describe real-world treatment patterns and …
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