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Found 165 Cancer trials

A listing of Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Randomized Phase II Trial Evaluating the Addition of the IGF-1R Monoclonal Antibody Ganitumab (AMG 479 NSC# 750008) to Multiagent Chemotherapy for Patients With Newly Diagnosed Metastatic Ewing Sarcoma

S
Sandeep Batra, MD
All genders
This randomized phase II trial studies how well combination chemotherapy with or without ganitumab works in treating patients with newly diagnosed Ewing sarcoma that has spread to other parts of the body.
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Randomized Double Blind Placebo Controlled Study of Erlotinib or Placebo in Patients With Completely Resected Epidermal Growth Factor Receptor (EGFR) Mutant Non-Small Cell Lung Cancer (NSCLC)

S
Shadia Jalal, MD
18-100 years
All genders
This randomized phase III trial studies how well erlotinib hydrochloride compared to placebo works in treating patients with stage IB-IIIA non-small cell lung cancer that has been completely removed by surgery.
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Adjuvant Nivolumab in Resected Lung Cancers (ANVIL) - A Randomized Phase III Study of Nivolumab After Surgical Resection and Adjuvant Chemotherapy in Non-small Cell Lung Cancers

S
Shadia Jalal, MD
18-100 years
All genders
This randomized phase III trial studies how well nivolumab after surgery and chemotherapy work in treating patients with stage IB-IIIA non-small cell lung cancer.
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A Phase II Trial of Chemotherapy plus Pembrolizumab in patients with advanced NSCLC previously treated with PD-1 or PD-L1 Inhibitor

G
Greg Durm, MD
18-100 years
All genders
This is a single-arm phase II study of continuation immunotherapy with pembrolizumab following initial benefit with a PD-1 or PD-L1 inhibitor.
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A Single Arm Phase II Study of ADjuvant Endocrine Therapy, Pertuzumab, and Trastuzumab for Patients With Anatomic Stage I Hormone Receptor-positive, HER2-positive Breast Cancer (ADEPT)

T
Tarah Ballinger, MD
18-100 years
All genders
Phase 2
Interventional
This research study is studying a combination of HER2-directed therapies (trastuzumab anduzumab) and hormonal therapy as a treatment after surgery for hormone receptor positive breast cancer. The study drugs involved in this study are: A combination of trastuzumab and pertuzumab given as an injection under the skin (PHESGO) Hormonal (endocrine) …
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Phase II open-label global study to evaluate the effect of dabrafenib in combination with trametinib in children and adolescent patients with BRAF V600 mutation positive Low Grade Glioma (LGG) or relapsed or refractory High Grade Glioma (HGG)

M
Michael Ferguson, MD
1-17 years
All genders
The purpose of this study is to investigate the activity of dabrafenib in combination with trametinib in children and adolescent patients with BRAF V600 mutation positive low grade glioma or relapsed or refractory high grade glioma.
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Effect of low intensity vibration (LIV) on aromatase inhibitor- induced musculoskeletal dysfunction in early stage breast cancer survivors

T
Tarah Ballinger, MD
18-100 years
Female
A type of breast cancer medicine called aromatase inhibitors (AI) causes muscle weakness and bone loss in patients. This research is being done to test whether low intensity vibration (LIV) can prevent the loss of muscle and bone strength in patients receiving AIs.
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Testicular Tissue Cryopreservation for Fertility Preservation

A
Amanda J. Saraf, DO
Male
Observational
Testicular tissue cryopreservation is an experimental procedure where a young boy'sular tissue is retrieved and frozen. This technique is reserved for young male patients who are not yet producing mature sperm, with the ultimate goal that their tissue may be usedhe future to restore fertility when experimental techniques emerge from …
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STEPS to Enhance Physical Activity (STEPS) after Hematopoietic Stem Cell Transplantation (HCT) for Multiple Myeloma

E
Eileen Hacker
18-100 years
All genders
The purpose of this pilot study is to test the preliminary effects of a free-living physical activity intervention, STEPS to Enhance Physical Activity (STEPS), compared to usual care on fatigue (tiredness), functional ability (ability to perform tasks associated with daily living, like moving from a sitting to standing position), muscle …
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ALTUS: Performance of a Multi- Target Hepatocellular Carcinoma (HCC) Test in Subjects With Increased Risk

N
Naga Chalasani, MD
18-100 years
All genders
Observational
The primary objective is to assess overall sensitivity and specificity of Oncoguard™ Liverhepatocellular cancer (HCC) detection in a surveillance population.
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