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Found 5 Glioma trials

A listing of Glioma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

S
Scott Coven
1 year - 25 years
All genders
Phase 1
Interventional
What is the purpose of this study?This phase I trial studies the side effects and best dose of trametinib and everolimus ing pediatric and young adult patients with gliomas that have come back (recurrent). Trametinib acts by targeting a protein in cells called MEK and disrupting tumor growth.verolimus is a …
M
Michael Ferguson, MD
25 years or below
All genders
Phase 3
Interventional
What is the purpose of this study?This is a 2-arm, randomized, open-label, multicenter, global, Phase 3 trial to evaluate the efficacy, safety, and tolerability of tovorafenib monotherapy versus standard of care (SoC) chemotherapy in patients with pediatric low-grade glioma (LGG) harboring an activating rapidly accelerated fibrosarcoma (RAF) alteration requiring front-line …
B
Brian Weiss
1 years - 21 years
All genders
Interventional
What is the purpose of this study?This phase I/II trial evaluates the best dose, side effects and possible benefit of CBL0137 in treating patients with solid tumors, including central nervous system (CNS) tumors or lymphoma that has come back (relapsed) or does not respond to treatment (refractory). Drugs, such as …
M
Mitesh Shah, MD
18 years - 100 years
All genders
Phase 4
Interventional
What is the purpose of this study?This study seeks to explore if GT, given its unique radiobiological and physical characteristics, may permit safe dose escalation and intensification and thereby provide a benefit to newly diagnosed GBM patients in terms of OS and LC when incorporated into the framework of the …
S
Scott Coven
20 years or below
All genders
Phase 2
What is the purpose of this study?The purpose of this study is to measure the benefit of adding abemaciclib to the chemotherapy, temozolomide, for newly diagnosed high-grade glioma following radiotherapy.Your participation could last approximately 11 months and possibly longer depending upon how you and your tumor respond.The purpose of this …