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Found 645 IU Health Enterprise System trials

A listing of IU Health Enterprise System medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Adaptation in the forearm bones of tennis players assessed using novel approaches

S
Stuart Warden
18 years - 24 years
Accepts healthy volunteer
Male
What is the purpose of this study?We are seeking adult males to participate in a study exploring the benefits of exercise on the human skeleton. and bone health. THIS STUDY IS ENROLLING BY INVITATION ONLY -   There will be two groups of participants--tennis players and controls. Tennis players will be …
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Investigation of CRF2 Agonist for Worsening Heart Failure

P
Peter Pang, MD
18 years - 85 years
All genders
Phase 2
Interventional
This study investigates the effects of an investigational medication on patients with worsening heart failure, a condition where the heart is not able to pump blood effectively. The purpose is to assess how different doses of a corticotropin-releasing factor type 2 (CRF2) peptide agonist affect patients who need urgent treatment …
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Studying Huntington's Disease: Observing Participants

C
Christopher James
100 years or below
Accepts healthy volunteer
All genders
This study investigates Huntington's disease (HD), a condition that affects the brain and causes movement, cognitive, and psychiatric disorders. The purpose of this study is to gather data on people with HD and their family members to better understand the disease. An observational study is a type of research study …
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Investigating Genetic and Blood Indicators in Lung Artery High Blood Pressure

R
Roberto Machado, MD
100 years or below
All genders
This study investigates pulmonary hypertension, a disease where the blood pressure in the lungs' arteries is too high, which can lead to heart problems. Pulmonary hypertension can be linked to other conditions like scleroderma, a condition that affects the skin and connective tissues, or be caused by certain drugs. The …
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Collection of Liver Tissue and a Blood Sample for Future Research

N
Naga Chalasani, MD
18 years or above
All genders
What is the purpose of this study?The aim of this study is to collect a small sample of liver tissue and approximately 15mL of blood from patients who are undergoing elective liver biopsies for clinical purposes to establish and grow a liver tissue bank.  The samples will be used for …
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Gastroschisis Outcomes of Delivery (GOOD) Study

H
Hiba Mustafa, MD
18 years or above
Female
Phase 3
Interventional
The objective of this study is to investigate the hypothesis that delivery at 35 0/7- 35 6/7 weeks in stable patients with gastroschisis is superior to observation and expectantgement with a goal of delivery at 38 0/7 - 38 6/7 weeks. To test this hypothesis, we willdomized, prospective, multi-institutional trial …
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Liver Stiffness in Patients with Underlying Polycystic Kidney Disorders.

J
Jean Molleston, MD
3 years - 65 years
All genders
Use Fibroscan to determine thevalence of CHF in an ADPKD population and the incidence over a four-yeard in these patients. Use Fibroscan to determine thevalence of congenital hepatic fibrosis in an ARPKD population Use fibroscan to determine thevalence of fibrotic liver disease in patients with other cystic kidneydiseases such as …
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Single Ventricle Risk Stratification and Outcomes (SVO)

S
Stephanie Ware, MD
5 years or below
All genders
This study may help link heart problems, or genetic defects, and physical features for certain heart defects. 
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Pediatric JIA Registry.

S
Stacey Tarvin, MD
6 years - 18 years
All genders
Children with juvenile idiopathic arthritis (JIA) can develop jaw damage when the jaw joints (temporomandibular joints or TMJ) are involved.  This jaw damage can cause pain on opening, pain on chewing and jaw growth problems leading to a small jaw with trouble opening the mouth. This registry would collect data …
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Personalized Perioperative Analgesia Platform (PPAP) for Pediatric Spine Fusion Surgery (sIRB) (PPAP Spine)

S
Senthil Packiasabapathy
10 years - 17 years
All genders
Interventional
The purpose of this collaborative CTSA application is to develop an innovative perioperativegesia platform (PPAP) to improve analgesia and reduce serious immediate andg-term adverse outcomes of perioperative opioids in children undergoing painful surgery.
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