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Found 645 iu-health-enterprise-system trials

A listing of iu-health-enterprise-system medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Research Study for Lung Condition

C
Cynthia Brown, MD
12 years or above
All genders
Phase 3
Interventional
This study investigates a potential treatment for bronchiectasis, a condition where the airways in the lungs become damaged, leading to a build-up of mucus and frequent lung infections. The purpose of this study is to observe the effects of an investigational medication taken by participants to see if it can …
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Role of Spiritual Well-Being in Kids with IBD

M
Marian Pfefferkorn
11 years - 18 years
All genders
Observational
This study investigates how spirituality and mood changes affect children with Pediatric Inflammatory Bowel Disease (PIBD). Inflammatory Bowel Disease, or IBD, makes parts of the intestine or bowel red and swollen. It is a long-lasting condition that can be constant or come and go. Many children with IBD also experience …
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Investigating Body Composition in Infants with Chronic Kidney Disease and End-Stage Renal Disease

M
Michelle C. Starr, MD
12 months or below
All genders
Observational
This study investigates the body composition of infants with chronic kidney disease (CKD) and end-stage renal disease (ESRD). CKD and ESRD are conditions where the kidneys are damaged and cannot work properly. This study aims to improve how doctors assess nutrition in these infants and help them grow better. The …
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Evaluation of a New Strategy for Protocolized Antibiotic Care for Severe Open Fractures: SEXTANT

K
Karl Shively
L
Luke A. Lopas, MD
18 years - 64 years
All genders
Phase 3
Interventional
The proposed study is a multi-center, prospective randomized controlled trial comparingurrent standard of care treatment to the SEXTANT treatment protocol in patients with Typeures of the tibia and IIIB fractures of the ankle and hindfoot.
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A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations

S
Sandeep Batra, MD
21 years or below
All genders
Phase 3
Interventional
What is the purpose of this study?This phase III trial compares standard chemotherapy to therapy with liposome-encapsulated daunorubicin-cytarabine (CPX-351) and/or gilteritinib for patients with newly diagnosed acuteyeloid leukemia with or without FLT3 mutations. Drugs used in chemotherapy, such as daunorubicin, cytarabine, and gemtuzumab ozogamicin, work in different ways to stop …
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Genomics of Obesity and Asthma – The Role of Adipose Tissue (GenOAAT)

E
Erick Forno
6 years - 24 years
Accepts healthy volunteer
All genders
Researchers at Indiana University School of Medicine are conducting a research study to better understand how obesity makes asthma and lung function worse. Obesity and asthma are two of the most important health problems affecting adolescents and adults. In the last few years, we haveund evidence that the amount of …
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Study of Investigational Medication to Investigate the Potential to Reduce Protein in Urine for Complement 3 Glomerulopathy

M
Myda Khalid
12 years - 60 years
All genders
Interventional
This study investigates the effects of an investigational medication compared to a placebo in people with Complement 3 Glomerulopathy (C3G), a kidney disease. C3G is a condition where a protein called complement 3 is deposited in the kidneys, causing damage. The purpose is to see if the investigational medication can …
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Biorepository for Adverse Drug Reaction (RADR)

E
Emma Tillman
1 years - 100 years
All genders
The primary objective of the Biorepository for Adverse Drug Reaction (RADR) will be to provide researchers with a bank of biological samples and clinical data related to investigate biomarkers of unexpected response following medicines and vaccines.
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Investigating Nasal Application of Povidone Iodine to Prevent Infections in Surgeries Related to Bones and Muscles

T
Todd McKinley, MD
18 years - 100 years
All genders
Phase 4
This study investigates whether applying povidone iodine (PVI) to the noses of patients undergoing leg, ankle, or foot surgeries can reduce the risk of infections at surgical sites, especially those caused by the bacteria Staphylococcus aureus. Patients with high-energy lower extremity fractures (HELEF) are at a higher risk for these …
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Evaluation of VX-121/Tezacaftor/Deutivacaftor in Cystic Fibrosis (CF) Participants 1 Through 11 Years of Age

J
James Chmiel
1 year - 11 years
All genders
Phase 3
Interventional
The purpose of this study is to evaluate the pharmacokinetics, safety, tolerability andy of VX-121/tezacaftor/deutivacaftor (VX-121/TEZ/D-IVA) in CF participants with at1 triple combination responsive (TCR) mutation in the cystic fibrosis transmembraneductance regulator (CFTR) gene.
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