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Found 648 iu-health-enterprise-system trials

A listing of iu-health-enterprise-system medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

E
Erik Imel, MD
5 years - 17 years
All genders
Phase 3
Interventional
What is the purpose of this study?The primary objective of this study is to evaluate the effect of romosozumab treatment for 12-months compared with bisphosphonate(s) on the number of clinical fractures at 12-months; the number of any fractures at 12-months and change in lumbar spine bone mineral density (BMD) Z-score …
C
Courtney Rowan, MD
1 years - 26 years
All genders
What is the purpose of this study?The goal of this study is to identify and validate response to therapy biomarkers for NIV respiratory support in children with ICCs. The central hypothesis is that response-to-therapy biomarkers can identify those most likely to benefit from intervention with NIV. The rationale is that …
M
Marissa Just
1 years - 21 years
All genders
Phase 2
This phase II trial tests how well nivolumab in combination with chemotherapy drugs along with radiation therapy works in treating patients with nasopharyngeal cancer. Immunotherapy with monoclonal antibodies, such as nivolumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to …
G
Greg Durm, MD
18 years or above
All genders
Phase 3
Interventional
What is the purpose of this study?The main objective is to compare the efficacy of tarlatamab with standard of care (SOC) on prolonging overall survival (OS).THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with most oncology trials, patients are not actively “recruited,” but are screened by their physician for …
V
Varun Mittal
18 years or above
All genders
Phase 2
Interventional
What is the purpose of this study?This is a research study being done to see if adding a drug called epcoritamab to “salvage chemotherapy” GDP (gemcitabine + cisplatin, with dexamethasone) will better treat cancer than using chemotherapy alone.  THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with most oncology …
M
Monika Fischer, MD
16 years - 75 years
All genders
Phase 3
Interventional
What is the purpose of this study?The purpose of this protocol is to evaluate the efficacy and safety of tulisokibart in participants with moderately to severely active Crohn's disease. The protocol consists of 2 studies. Study 1 includes induction and maintenance treatment, and Study 2 includes only induction treatment. Each study …
P
Paul Musey, MD
18 years - 55 years
All genders
Interventional
This study investigates the effects of an investigational medication on reducing acute stress reactions and acute stress disorder following a motor vehicle collision. Acute stress reactions are immediate psychological responses to a traumatic event, which can develop into acute stress disorder if symptoms persist. The purpose of this study is …
A
Ajay Gupta
18 years - 100 years
All genders
Phase 3
Interventional
This study investigates the long-term safety and tolerability of an investigational medication in adults with different types of multiple sclerosis (MS), including relapsing MS, primary progressive MS, and nonrelapsing secondary progressive MS. Multiple sclerosis is a disease where the immune system attacks the protective covering of nerves, leading to communication …
J
Julian Marin Acevedo
18 years - 100 years
All genders
What is the purpose of this study?The primary objective of this study is to estimate the proportion of individuals with lung cancer seen at Indiana University and Eskenazi Health Centers who do not meet the 2021 USPSTF criteria for lung cancer screening. THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent …
J
Jamie Felton
100 years or below
All genders
Observational
What is the purpose of this study?The purpose of this research is to collect general information on patients with stage 2 type 1 diabetes (T1D) and further information on the long-term effects of TZIELD® in patients with Stage 2 T1D, treated as per standard of care.  THIS STUDY IS ENROLLING BY …
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