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Found 648 iu-health-enterprise-system trials

A listing of iu-health-enterprise-system medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

M
Mitesh Shah, MD
100 years or below
All genders
Observational
What is the purpose of this study?The objectives of this registry study are to evaluate real-world clinical outcomes andd outcomes that measure the effectiveness and safety of STaRT.THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with most oncology trials, patients are not actively “recruited,” but are screened by their …
A
Andrew Schwaderer, MD
7 years - 17 years
All genders
Observational
What is the purpose of this study?The purpose of this study is to develop a test for kidney disease that does not require a kidney biopsy or blood draw.  We will look at urine samples under a microscope and see if we find patterns in the kind of cells and …
J
James Chmiel
1 year - 11 years
All genders
Phase 3
Interventional
The purpose of this study is to evaluate the pharmacokinetics, safety, tolerability andy of VX-121/tezacaftor/deutivacaftor (VX-121/TEZ/D-IVA) in CF participants with at1 triple combination responsive (TCR) mutation in the cystic fibrosis transmembraneductance regulator (CFTR) gene.
E
Erika Daley
4 years - 10 years
All genders
Interventional
This protocol describes a multicenter, prospective randomized superiority trial comparingunctional outcomes between children treated with sedated reduction versus no formalduction.
K
Kate Hawa
2 years - 21 years
Accepts healthy volunteer
All genders
Phase 4
This study will evaluate changes in the fecal microbiome in constipated pediatric patients before and after antegrade continence enema placement and initiation of antegrade enemaushes. Subjects will have their microbiome sequenced prior to placement by obtaining a. Pre-antegrade continence enema placement results will be compared to fecalbtained at 0, 4, …
M
Marcia Felker, MD
4 years - 5 years
Male
Phase 4
Observational
What is the purpose of this study?This is a multicenter, prospective, observational Phase 4 study in the United States. The study is designed to collect both medical history and prospective data on Duchenne muscular dystrophy (DMD) treatment outcomes in participants receiving delandistrogene moxeparvovec as part of clinical care, compared to …
K
Kathryn Nevel
18 years - 100 years
All genders
Phase 3
What is the purpose of this study?The brain is protected from any toxic or inflammatory molecule by the blood-brain barrier (BBB). This physical barrier is located at the level of the blood vessel walls. Because of these barrier properties, the blood vessels are also impermeable to the passage of therapeutic …
S
Steven Rhodes
1 years - 8 years
All genders
Phase 2
This study investigates the use of an investigational medication to prevent the growth of plexiform neurofibromas in children with Neurofibromatosis Type 1 (NF1). NF1 is a genetic disorder that often causes tumors to grow on nerve tissues, which can lead to various health problems. The study aims to see if …
R
Raj Vuppalanchi, MD
18 years - 75 years
All genders
Phase 3
Interventional
Why is this study being done?In some people, the liver makes an abnormal version of the alpha-1 antitrypsin (AAT) protein, called Z-AAT. Making an abnormal version of the AAT protein can result in liver disease as Z-AAT builds up in liver cells, which leads to liver problems such as liver …
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Attaya Suvannasankha, MD
18 years - 95 years
All genders
This study investigates a treatment for multiple myeloma, a type of cancer that affects plasma cells in the bone marrow. The purpose of the study is to see if the investigational treatment can improve cancer outcomes and bone health.Participants will have standard clinical assessments, such as blood draws and bone …
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