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Found 594 results for iu-health-enterprise-system

A listing of iu-health-enterprise-system medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

A Phase III, Randomised, Double-blind Study to Evaluate the Effect of Balcinrenone/Dapagliflozin, Compared with Dapagliflozin, on the Risk of Heart Failure Events and Cardiovascular Death in Patients with Heart Failure and Impaired Kidney Function

W
Wayne Gray
18 years - 100 years
All genders
Phase 3
Interventional
The purpose of this study is to investigate the effect of balcinrenone/dapagliflozin compared with dapagliflozin, on the risk of CV death, HF event with and without hospitalization, in patients with chronic HF, impaired kidney function, and who have had a recent HF event.THIS STUDY IS ENROLLING BY INVITATION ONLY

Offspring Neurodevelopment and Growth after Early Antihypertensive Therapy or Preeclampsia in Women with Chronic Hypertension and Pregnancy (CHAP Child)

D
David Haas, MD
All genders
Observational
What is the purpose of this study?This study is being conducted to evaluate the current state of knowledge regarding long-term child outcomes among children born to women with mild CHTN who received antihypertensive therapy in pregnancy or who had preeclampsia. This study will compare long-term outcomes, including neurodevelopment and growth. …

A Phase 3, Prospective, Open-label, Uncontrolled, Multicenter Study onEfficacy and Safety of Prophylaxis with rVWF in Children Diagnosed With Severe von Willebrand disease

K
Kerry Hege, MD
All genders
Phase 3
Interventional
What is the purpose of this study?The main aim of the study is to evaluate the effectiveness of prophylaxis with recombinant von Willebrand factor (rVWF) in children. This study will enroll those participants who have been previously treated with VWF product or with a plasma-derived VWF (pdVWF) product.  

A Registry Study for Children with Atypical Teratoid Rhabdoid Tumor (ATRT)

S
Scott Coven
All genders
 Study goals:To analyze the significance of treatment, clinical and molecular variables in predicting progression free survival (PFS) at 6 months (PFS6) from date of diagnosis.To create a well annotated ATRT biorepository for current and future studies through the collection of biospecimens, imaging and key clinical data.THIS STUDY IS ENROLLING BY …

Advanced Cardiac Therapies Improving Outcomes Network to Improve the Health of Pediatric and Congenital Heart Disease Patients with Heart Failure

J
John Parent, MD
All genders
What is the purpose of this study?Our goal is to partner with patients who have heart failure and their families to achieve improved outcomes and quality of life. In addition, the network will provide an ideal platform for clinical, translational, and comparative effectiveness research.THIS STUDY IS ENROLLING BY INVITATION ONLY …

Application of Cellie Coping Kits in Pediatric Patients with Eosinophilic Esophagitis (EoE)

P
Paroma Bose, MD
2 years - 18 years
All genders
Interventional
What is the purpose of this study?The aim of this study is to measure the efficacy of the Cellie Coping Kit in pediatric patients with EoE.  Furthermore, an additional aim is to determine if there is variation in the kit’s efficacy among patients being treated with diet elimination versus medications …

Validation of Early Prognostic Data for Recovery Outcome after Stroke for Future, Higher Yield Trials

A
Ann Marie Jones
18 years - 100 years
All genders
Observational
What is the purpose of this study?Currently, 7 million US stroke survivors have significant disability, more than half with residual motor deficits. Motor function, particularly of the upper extremity (UE), is critical for regaining independence after stroke. VERIFY will validate biomarkers of upper extremity (UE) motor outcome in the acute …

Continuous Glucose Monitor Derived Glucose Dynamic Index as a Diagnostic Marker for Progression to Type 1 Diabetes (Dx-T1D)

V
Viral Shah
4 years - 100 years
All genders
Observational
This study is being done to develop a way to use information from a continuous glucose monitor (CGM) to predict a person’s progression through the Stages of Type 1 Diabetes (T1D).A CGM is a wearable device that continuously measures and displays a person’s blood sugar levels throughout the day and …

FERN-International: Management of Selective Fetal Growth Restriction in Monochorionic Twin Pregnancy: A multicentre prospective observational study

H
Hiba Mustafa, MD
18 years - 100 years
Female
Observational
What is the purpose of this study?To study perinatal outcomes and management options in monochorionic (MC) twin pregnancies with selective fetal growth Restriction (sFGR)THIS STUDY IS ENROLLING BY INVITATION ONLY - The standard of care at our MFM practice is that monochorionic twin pregnancies complicated with selective fetal growth restriction …

Workforce and System Change to Treat Adolescent Opioid Use Disorder within Integrated Pediatric Primary Care

L
Leslie Hulvershorn, MD, MSc
12 years - 100 years
All genders
Interventional
What is the purpose of this study?This project seeks to address the increasing risk of overdose death, substance use disorder (SUD), and opioid use disorder (OUD) in adolescents. The investigators believe that pediatric primary care providers (PCP) could play an important role in helping youth with SUD because most adolescents …
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