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Found 645 iu-health-enterprise-system trials

A listing of iu-health-enterprise-system medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Investigating Dialysis Access Methods in Female Patients with Kidney Failure

D
David A. Peterson, MD
18 years or above
Female
Phase 3
Interventional
This study investigates the differences between two dialysis access methods in female patients with end-stage renal disease (ESRD) who need hemodialysis. The purpose is to compare catheter-free days and infection severity between patients using two different types of access methods over 12 months.Participants will be randomly assigned to one of …
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Primary Ciliary Dyskinesia Registry

E
Evans Machogu, MD
90 years or below
All genders
Our purpose for this research study is to learn more about Primary Ciliary Dyskinesia (PCD) through the creation of a secure electronic clinical registry. Through this registry, we will be able to follow people living with PCD over time to learn more about how PCD affects people’s health and the treatment people …
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Blood Collection for Research Studies Related to Asthma, Cystic Fibrosis and Other Pulmonary Disorders

K
Kirsten Kloepfer, MD
5 years - 100 years
Accepts healthy volunteer
All genders
What is the purpose of this study?The purpose of this study is to collect blood samples from people ages 5 years and older who are healthy volunteers or patients with CF or other pulmonary disorders. The blood samples will be used for a variety of studies related to CF, asthma, …
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Sympathetic Nerve Activity and Cardiovascular Events

T
Thomas Everett
18 years - 100 years
All genders
What is the purpose of this study?The purpose of this study is to test the hypothesis that skin sympathetic nerve activity (SKNA) can be used as a biomarker for physiological events including predicting neurological recovery during supportive care for cardiac arrest, and to risk stratify patients for recurrence of atrial …
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Study on Investigational Medication for Depressive Episodes in Youth with Bipolar Disorder

L
Leslie Hulvershorn, MD, MSc
10 years - 17 years
All genders
Interventional
This study investigates the use of an investigational medication for treating depressive episodes in young people aged 10 to 17 years with Bipolar I Disorder. The study aims to see if the investigational medication is safe and works well in young people.Bipolar I Disorder is a mental health condition that …
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Pursuing Exploration into the Supportive Care Needs and Intervention Preferences of Survivors of Testicular Cancer (PERSIST): A Mixed Methods Pilot Study

S
Shelley Johns
18 years or above
Male
What is the purpose of this study?In this 3-phase pilot, we will identify adverse health outcomes and unmet support needs of testicular cancer survivors (TCS) (Phase 1) and employ participatory co-design to adapt an existing acceptance and commitment therapy (ACT)-based intervention with a sample of up to 8 TCS (Phase …
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Azithromycin Treatment for Respiratory Syncytial Virus-induced Respiratory Failure in Children

M
Michael Hobson, MD
3 days - 2 years
All genders
Interventional
What is the purpose of this study?The overarching hypothesis of the ARRC trial is that administration of Azithromycin (AZM) during acute, Respiratory Syncytial Virus (RSV)-induced respiratory failure will be beneficial, mediated through the matrix metalloproteinase (MMP)-9 pathway. THIS STUDY IS ENROLLING BY INVITATION ONLY
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A Global Multi-Center Prospective Observational Cohort to Support Drug Development in Adult Patients with Primary Sclerosing Cholangitis

C
Craig Lammert, MD
18 years - 75 years
All genders
Observational
What is the purpose of this study?To develop an appropriate real-world data comparator cohort to support the design, execution, and serve as an external control for interventional clinical trials in PSC. This is a Global, multi-center longitudinal observational cohort study. Collection of prospective clinical data to include liver-related clinical outcomes …
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Pediatric Behavioral Health Integrated Care: Indiana Statewide Strategic Plan to Address the Growing Mental Health Crisis

M
Matthew Aalsma
18 years - 100 years
All genders
Observational
What is the purpose of this study?The purpose of this study is to learn more about the impact of a substance use disorder (SUD) Integrated Behavioral Health Program (IBH) on primary care providers (PCPs) willingness to engage in and views/attitudes around adolescent SUD treatment as well as IBH team dynamics.  THIS …
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Role of neutrophil-specific NOX2 in alcohol-induced liver injury

S
Suthat Liangpunsakul, MD
18 years - 70 years
Accepts healthy volunteer
All genders
What is the purpose of this study?NADPH oxidase 2 (NOX2) is the isoform of NOX found in phagocytes including neutrophils, NOX2 activation generates reactive oxygen species (ROS) with antimicrobial activities. Patients with advanced alcoholic cirrhosis or alcoholic hepatitis are more susceptible to infections due to deficient ROS production by neutrophils. …
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