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Found 607 iu-health-enterprise-system trials

A listing of iu-health-enterprise-system medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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C
Cynthia Bodkin, MD
18 years - 100 years
All genders
Observational
What is the purpose of this study?PREVENT ALL ALS is a prospective, observational cohort study enrolling individuals at risk for carrying inherited genetic variants known to be causative for ALS. This is a longitudinal observational study involving collection of clinical data, outcomes andbiofluid samples. There is also an optional sub-study …
K
Kenneth Lim
18 years - 100 years
All genders
Interventional
What is the purpose of this study?The purpose of the study is to assess the therapeutic benefits of sodium-glucose cotransporter 2 (SGLT2) inhibitors in improving physical function in End Stage Renal disease (ESRD) patients.  The study is using the drug Empagliflozin, a FDA approved drug for patients with advanced CKD. …
B
Babar Khan, MD
50 years - 100 years
All genders
Interventional
What is the purpose of this study?Depression affects one-third of intensive care unit (ICU) survivors and represents a potentially modifiable target to slow cognitive decline and reduce the risk of Alzheimer’s disease and related dementias (ADRD). Our multi-PI team proposes a two-arm RCT called ADEPT-ICU (Attenuating DEPression with Internet CBT …
N
Noel Dasgupta
18 years - 100 years
All genders
Phase 3
Interventional
What is the purpose of this study?To evaluate the efficacy and safety of a single dose of NTLA-2001 compared to placebo in participants with ATTR-CM. 
M
Melissa Lah, MD
100 years or below
All genders
Observational
This study investigates the effects of long-term treatment on people with phenylketonuria (PKU), a condition where the body cannot break down an amino acid called phenylalanine, which can lead to harmful levels in the body. The purpose of this study is to evaluate immune and inflammatory responses in participants receiving …
S
Sandeep Batra, MD
29 days - 21 years
All genders
Phase 3
This study investigates the treatment of acute myeloid leukemia (AML) in children, adolescents, and young adults who have experienced a relapse. The purpose is to see if adding an investigational medication to a standard chemotherapy treatment can improve outcomes. Acute myeloid leukemia is a type of cancer that affects the …
C
Cary Mariash, MD
18 years - 75 years
All genders
Phase 2/3
Interventional
This is a study to assess the efficacy, safety, and tolerability of IMVT-1402 in adult participants with Graves' disease (GD) who are hyperthyroid despite antithyroid drug (ATD) treatment.The primary objective of this study is to evaluate the efficacy of IMVT-1402 versus placebo as assessed by T3 (total triiodothyronine [T3] or …
J
Joel Corvera, MD
18 years - 100 years
All genders
Observational
An observational, prospective multi-regional post-market registry collecting mid- and long-term data to assess outcomes through ten years of follow-up for subjects treated with GORE® TAG® Conformable Thoracic Stent Graft with ACTIVE CONTROL System as a part of routine clinical practice. This post-market registry for the GORE® TAG® Conformable Thoracic Stent …
H
Hiba Mustafa, MD
100 years or below
All genders
This study investigates the condition known as Hemolytic Disease of the Fetus and Newborn (HDFN). HDFN occurs when a pregnant person's immune system attacks the red blood cells of their fetus, leading to anemia and other complications. This study is a global, prospective registry that collects data from pregnant individuals …
M
Marissa Just
30 years or below
All genders
Phase 3
This study investigates treatment strategies for children with favorable histology Wilms tumors (FHWT), which is a common type of kidney cancer in children. The study aims to use risk factors, such as tumor histology, biology, and response to therapy, to determine the most effective treatment plan. Wilms Tumor is a …
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