A listing of site-public-contact medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
This study investigates the treatment of breast cancer in patients who have hormone-sensitive, HER-2 negative tumors with a low recurrence score. The purpose is to understand if breast conservation surgery with only endocrine therapy is as effective as combining it with radiation therapy in preventing the return of cancer in …
This study investigates the use of circulating tumor DNA (ctDNA) to personalize treatment for patients with stage III non-small cell lung cancer (NSCLC). The purpose is to use ctDNA analysis to guide therapy decisions, instead of relying solely on clinical or radiographic evidence of disease. This approach aims to tailor …
This study investigates treatments for patients with residual triple negative breast cancer, a type of breast cancer that does not have estrogen, progesterone, or HER2 receptors. The study uses circulating tumor DNA (ctDNA) to assign participants to different treatment arms based on their genomic markers. Participants with ctDNA positivity and …
This study investigates treatments for people with HER2-positive breast cancer. HER2-positive means that the cancer cells have more HER2 protein than normal, which can cause cancer cells to grow. The study looks at using a combination of investigational medication injections and hormone therapy after surgery. The investigational medications are trastuzumab …
This study investigates the effects of an investigational medication alone compared to the same medication combined with tocilizumab in patients with advanced breast cancer. Advanced breast cancer includes conditions such as metastatic triple negative or ER-low breast cancer. This study involves Black and non-Black patients and aims to understand how …
This study investigates treatments for women with platinum-resistant epithelial ovarian cancer, which is a type of cancer that does not respond to platinum-based chemotherapy. The purpose is to compare the effects of different treatments, including an investigational medication called nemvaleukin, either alone or in combination with another treatment, pembrolizumab, against …
This study investigates maintenance treatment with oral etoposide or observation in patients with relapsed germ cell tumors (GCT) who have received high-dose chemotherapy and peripheral blood stem cell transplant. Germ cell tumors are a type of cancer that begins in the cells that give rise to sperm or eggs. This …
This study investigates the use of an investigational medication along with a targeted therapy called olaparib for patients with metastatic pancreatic cancer. Metastatic pancreatic cancer is when the cancer has spread from the pancreas to other parts of the body. The study focuses on patients with specific genetic mutations called …
This study investigates the use of abatacept in patients who have myocarditis, a heart condition, after being treated with immune checkpoint inhibitors (ICI). The purpose is to see if abatacept can lower the risk of major adverse cardiac events (MACE), which include serious heart problems like heart attacks or heart …
This study investigates the feasibility of adding pre-rehabilitation pelvic health physical therapy to the standard radiation treatment plan for women with certain types of cancer. These include cervical, vaginal, vulvar, uterine, or anal cancer. Participants will receive education on using a vaginal dilator during their treatment. The study will also …
