A listing of site-public-contact medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
This study investigates the effects of adding an investigational medication, cemiplimab, to the usual treatment of docetaxel and ramucirumab for patients with stage IV or recurrent non-small cell lung cancer. This type of lung cancer is advanced and may have returned after previous treatment. Cemiplimab is a monoclonal antibody that …
What is the purpose of this study?This phase III trial compares the effect of stereotactic radiosurgery to standard of care memantine and whole brain radiation therapy that avoids the hippocampus (the memory zone of the brain) for the treatment of small cell lung cancer that has spread to the brain. …
This study investigates the effects of adding an investigational medication to a standard treatment for patients with high-risk renal cell carcinoma (RCC). RCC is a type of kidney cancer. The purpose of this study is to see if the investigational medication, when combined with the standard treatment, works better than …
The purpose of this study is to investigate the use of an investigational medication as a maintenance therapy for patients with multiple myeloma after they have undergone an autologous stem cell transplant. Multiple myeloma is a type of cancer that affects plasma cells in the bone marrow. This study aims …
This study investigates the effect of adding radiation therapy to usual care for patients with high-risk asymptomatic bone metastases. Bone metastases are cancer cells that have spread to the bones. High-risk means they are more likely to cause problems like fractures or pain. Radiation therapy uses powerful x-rays to kill …
What is the purpose of this study?This phase II Expanded Lung-MAP treatment trial tests how well amivantamab-subcutaneous (SC) works in treating patients patients with MET amplification non-small cell lung cancer. Amivantamab-SC is a drug that reduces extra copies of the MET gene, a change present in your tumor. Giving amivantamab-SC …
This study investigates the effectiveness and safety of an investigational medication compared to the investigator's choice of monotherapy treatment in patients with head and neck squamous cell carcinoma (HNSCC) that is incurable, metastatic, or recurrent. HNSCC is a type of cancer that occurs in the squamous cells lining the head …
This study investigates the safety and appropriate dosage of an investigational medication given to patients during breast-conserving surgery for breast cancer. Breast-conserving surgery involves removing the cancer while keeping as much normal breast as possible. The investigational medication is administered directly to the surgical site to assess its effects on …
This study investigates an investigational gene therapy for adults with advanced or metastatic solid tumors. The purpose is to activate the immune system to fight cancer using a gene therapy vector, which is a non-replicating product designed to target cancer cells. The gene therapy includes a suicide gene that, with …
What is the purpose of this study?Primary Objectives1. To determine the safety and toxicity profile of a chimeric HER2 B-cell peptide vaccine in patients with high-risk HER2 positive breast cancer after completion of standard curative therapy and adjuvant HER2-directed antibody therapy2. To determine immune responses induced by a chimeric HER2 …
