A listing of site-public-contact medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
This study investigates the effectiveness and safety of an investigational medication compared to the investigator's choice of monotherapy treatment in patients with head and neck squamous cell carcinoma (HNSCC) that is incurable, metastatic, or recurrent. HNSCC is a type of cancer that occurs in the squamous cells lining the head …
This study investigates how safe and effective two investigational agents, an imaging agent and a therapeutic agent, are for patients with advanced breast cancer. The imaging agent, called 68Ga-R11228, is used to locate specific tumor cells in the body. The therapeutic agent, 177Lu-R11228, is used for treatment. Both agents are …
This study investigates the safety and appropriate dosage of an investigational medication given to patients during breast-conserving surgery for breast cancer. Breast-conserving surgery involves removing the cancer while keeping as much normal breast as possible. The investigational medication is administered directly to the surgical site to assess its effects on …
What is the purpose of this study?Primary Objectives1. To determine the safety and toxicity profile of a chimeric HER2 B-cell peptide vaccine in patients with high-risk HER2 positive breast cancer after completion of standard curative therapy and adjuvant HER2-directed antibody therapy2. To determine immune responses induced by a chimeric HER2 …
This study investigates how patients with CLL/SLL make decisions about their treatment options. CLL stands for chronic lymphocytic leukemia, and SLL stands for small lymphocytic lymphoma, both of which are types of blood cancers. The study aims to understand patient perspectives on choosing between different treatments and to gather feedback …
What is the purpose of this study?This phase II trial compares the effect of immunotherapy (pembrolizumab) plus chemotherapy (doxorubicin) to chemotherapy (doxorubicin) alone in treating patients with undifferentiated pleomorphic sarcoma (UPS) or a related poorly differentiated sarcoma that has spread from where it first started to other places in the …
What is the purpose of this study?The goal of this study (iMMagine-3) is to compare the study drug, anitocabtagene autoleucel to standard of care therapy (SOCT) in participants with relapsed/refractory multiple myeloma who have received 1 to 3 prior lines of therapy, including an anti-CD38 monoclonal antibody and an immunomodulatory …
This study investigates the effects of an investigational medication on appetite loss in patients with advanced cancer. Advanced cancer means the cancer has spread to other parts of the body. The purpose of this study is to compare the investigational medication with another usual medication to see which one is …
This study investigates the safety and effects of a combination treatment for locally advanced or metastatic breast cancer. Breast cancer is a disease where cells in the breast grow out of control. This study looks at an investigational medication made from the patient's own T cells, which are a type …
This study investigates muscle-invasive bladder cancer, a type of cancer that grows into the muscle layer of the bladder. The purpose is to see how well an investigational medication combined with another treatment works for this type of cancer. The study involves patients with muscle-invasive bladder cancer receiving treatment and …